Publications by authors named "Isabelle Becher"

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Defining basic rules for hardening influenza A virus liquid condensates.
Temitope Akhigbe Etibor, Silvia Vale-Costa, Sindhuja Sridharan, Daniela Brás, Isabelle Becher, Victor Hugo Mello, Filipe Ferreira, Marta Alenquer, Mikhail M Savitski, Maria-João Amorim

April 2023

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High-throughput peptide-centric local stability assay extends protein-ligand identification to membrane proteins, tissues and bacteria.
Kejia Li, Clement M Potel, Isabelle Becher, Nico Hüttmann, Martin Garrido-Rodriguez

Nat Struct Mol Biol· November 2025

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Uncovering protein glycosylation dynamics and heterogeneity using deep quantitative glycoprofiling (DQGlyco).
Clément M Potel, Mira Lea Burtscher, Martin Garrido-Rodriguez, Amber Brauer-Nikonow, Isabelle Becher

Nat Struct Mol Biol· June 2025

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Jumbo phage killer immune system targets early infection of nucleus-forming phages.
Li Yuping, Linlin Guan, Isabelle Becher, Kira S Makarova, Xueli Cao

Cell· April 2025

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Highly potent quinoxalinediones inhibit α-hemolysin and ameliorate Staphylococcus aureus lung infections.
Aditya Shekhar, Raffaella Di Lucrezia, Karoline Jerye, Vadim S Korotkov, Kirsten Harmrolfs, Isabelle Becher

Cell Host Microbe· April 2025

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Dextromethorphan inhibits collagen and collagen-like cargo secretion to ameliorate lung fibrosis.
Muzamil M Khan, George Galea, Juan Jung, Joanna Zukowska, David Lauer, Isabelle Becher

Sci Transl Med· December 2024

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Molecular profiling of sponge deflation reveals an ancient relaxant-inflammatory response.
Fabian Ruperti, Isabelle Becher, Anniek Stokkermans, Ling Wang, Nick Marschlich

Curr Biol· January 2024

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STPP-UP: An alternative method for drug target identification using protein thermal stability.
Dick W Zijlmans, Miguel Hernández-Quiles, Pascal W T C Jansen, Isabelle Becher, Frank Stein

J Biol Chem· November 2023

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Deep thermal profiling for detection of functional proteoform groups.
Nils Kurzawa, Isabelle Rose Leo, Matthias Stahl, Elena Kunold, Isabelle Becher

Nat Chem Biol· August 2023

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Molecular profiling of sponge deflation reveals an ancient relaxant-inflammatory response.
Fabian Ruperti, Isabelle Becher, Anniek Stokkermans, Ling Wang, Nick Marschlich

bioRxiv· August 2023

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Dual truncation of tau by caspase-2 accelerates its CHIP-mediated degradation.
Lydia Reinhardt, Fabrizio Musacchio, Maria Bichmann, Annika Behrendt, Ebru Ercan-Herbst, Isabelle Becher

Neurobiol Dis· June 2023

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Molecular mechanisms of stress-induced reactivation in mumps virus condensates.
Xiaojie Zhang, Sindhuja Sridharan, Ievgeniia Zagoriy, Christina Eugster Oegema, Cyan Ching, Isabelle Becher

Cell· April 2023

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Author Correction: A computational method for detection of ligand-binding proteins from dose range thermal proteome profiles.
Nils Kurzawa, Isabelle Becher, Sindhuja Sridharan, Holger Franken, André Mateus

Nat Commun· December 2021

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Impact of phosphorylation on thermal stability of proteins.
Clément M Potel, Nils Kurzawa, Isabelle Becher, Athanasios Typas, André Mateus

Nat Methods· July 2021

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Isocotoin suppresses hepatitis E virus replication through inhibition of heat shock protein 90.
Ila Nimgaonkar, Nicholas F Archer, Isabelle Becher, Mohammad Shahrad, Robert A LeDesma

Antiviral Res· January 2021

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Cell surface thermal proteome profiling tracks perturbations and drug targets on the plasma membrane.
Mathias Kalxdorf, Ina Günthner, Isabelle Becher, Nils Kurzawa, Sascha Knecht

Nat Methods· January 2021

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A computational method for detection of ligand-binding proteins from dose range thermal proteome profiles.
Nils Kurzawa, Isabelle Becher, Sindhuja Sridharan, Holger Franken, André Mateus

Nat Commun· November 2020

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Meltome atlas-thermal proteome stability across the tree of life.
Anna Jarzab, Nils Kurzawa, Thomas Hopf, Matthias Moerch, Jana Zecha, Isabelle Becher

Nat Methods· May 2020

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Identifying drug targets in tissues and whole blood with thermal-shift profiling.
Jessica Perrin, Thilo Werner, Nils Kurzawa, Anna Rutkowska, Dorothee D Childs, Isabelle Becher

Nat Biotechnol· March 2020

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Thermal proteome profiling for interrogating protein interactions.
André Mateus, Nils Kurzawa, Isabelle Becher, Sindhuja Sridharan, Dominic Helm

Mol Syst Biol· March 2020

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Pervasive Protein Thermal Stability Variation during the Cell Cycle.
Isabelle Becher, Amparo Andrés-Pons, Natalie Romanov, Frank Stein, Maike Schramm

Cell· May 2018

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Multiplexed Proteome Dynamics Profiling Reveals Mechanisms Controlling Protein Homeostasis.
Mikhail M Savitski, Nico Zinn, Maria Faelth-Savitski, Daniel Poeckel, Stephan Gade, Isabelle Becher

Cell· March 2018

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Systematic analysis of protein turnover in primary cells.
Toby Mathieson, Holger Franken, Jan Kosinski, Nils Kurzawa, Nico Zinn, Isabelle Becher

Nat Commun· February 2018

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Thermal profiling reveals phenylalanine hydroxylase as an off-target of panobinostat.
Isabelle Becher, Thilo Werner, Carola Doce, Esther A Zaal, Ina Tögel

Nat Chem Biol· November 2016

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GSK6853, a Chemical Probe for Inhibition of the BRPF1 Bromodomain.
Paul Bamborough, Heather A Barnett, Isabelle Becher, Mark J Bird, Chun-Wa Chung

ACS Med Chem Lett· June 2016

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