Publications by authors named "J Gosset"

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Effect of Varying Degrees of Hepatic Impairment on the Pharmacokinetics of Ervogastat, a Diacylglycerol Acyltransferase 2 (DGAT2) Inhibitor, and Clesacostat, an Acetyl-CoA Carboxylase (ACC) Inhibitor.
Manoli Vourvahis, Arthur J Bergman, Adam G Ogden, Jim Hughes, James R Gosset

J Clin Pharmacol· December 2025

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Considerations from the pharmaceutical industry (IQ MPS Affiliate) workshop on animal microphysiological systems and 3Rs in drug development.
Patrick J Devine, Manti Guha, Jason E Ekert, Anna K Kopec, James R Gosset

ALTEX· July 2025

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Towards in vitro models for reducing or replacing the use of animals in drug testing.
David M Stresser, Anna K Kopec, Philip Hewitt, Rhiannon N Hardwick, Terry R Van Vleet, James R Gosset

Nat Biomed Eng· August 2024

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The Current Status and Use of Microphysiological Systems by the Pharmaceutical Industry: The International Consortium for Innovation and Quality Microphysiological Systems Affiliate Survey and Commentary.
Thomas K Baker, Terry R Van Vleet, Prathap Kumar Mahalingaiah, Taraka Sai Pavan Grandhi, Raymond Evers, James R Gosset

Drug Metab Dispos· February 2024

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Investigation of pharmacokinetic drug interaction between clesacostat and DGAT2 inhibitor ervogastat in healthy adult participants.
Aarti Sawant-Basak, Arthur J Bergman, Jessica Mancuso, Sakambari Tripathy, James R Gosset

Clin Transl Sci· February 2024

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