Publications by authors named "J-P Roy"

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Covalent inhibitors of the PI3Kα RAS binding domain impair tumor growth driven by RAS and HER2.
Joseph E Klebba, Nilotpal Roy, Steffen M Bernard, Stephanie Grabow, Melissa A Hoffman

Science· November 2025

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Outcomes of Witnessed Versus Unwitnessed Patients With Stroke After Endovascular Therapy in the Extended Time Window.
Liisa Tomppo, Nicolas Martinez-Majander, Muhammad M Qureshi, Thanh N Nguyen, Raul G Nogueira, Daniel Roy

Stroke· November 2025

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Frustration in the protein-protein interface plays a central role in the cooperativity of PROTAC ternary complexes.
Ning Ma, Supriyo Bhattacharya, Sanychen Muk, Zuzana Jandova, Philipp S Schmalhorst, Michael J Roy

Nat Commun· September 2025

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Plasma Proteomics Reveals Dysregulated Pathways Across the Spectrum Cardiomyopathy.
Usman A Tahir, Daniel Reichart, Anisha Purohit, Jacob L Barber, Gaurav Tiwari, Darius Roy

Circ Genom Precis Med· August 2025

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First Use of Phage Therapy in Canada for the Treatment of a Life-Threatening, Multidrug-Resistant Periprosthetic Joint Infection.
Melissa T Cammuso, Bradley W M Cook, D William Cameron, Stephen Ryan, Marielou Tamayo, Riya Roy

Viruses· August 2025

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Electronic Informed Consent in the Multi-Arm Optimization of Stroke Thrombolysis Trial.
S Iris Davis, Abbey Staugaitis, Ian Rines, Akash Roy, Anthony D Rogers

Stroke· July 2025

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Endovascular Therapy for Late-Window M2-Segment Middle Cerebral Artery Occlusion: Analysis of the CLEAR Study.
Simon Winzer, Daniel P O Kaiser, Muhammad M Qureshi, Alicia C Castonguay, Daniel Strbian, Daniel Roy

Stroke· July 2025

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Immunocompetent cell targeting by food-additive titanium dioxide.
John W Wills, Alicja Dabrowska, Jack Robertson, Michelle Miniter, Sebastian Riedle, Nicole C Roy

Nat Commun· July 2025

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A Buccal Mucosal Oximeter Accurately Measures Arterial Oxyhemoglobin Saturation.
Connor Snow, Shane Magnison-Benoit, Matiram Pun, Thomas R Tripp, Aimee Clarke, Steven Roy

Med Devices (Auckl)· July 2025

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MicroRNA-15a-5p mediates abdominal aortic aneurysm progression and serves as a potential diagnostic and prognostic circulating biomarker.
Greg Winski, Ekaterina Chernogubova, Albert Busch, Suzanne M Eken, Hong Jin, Joy Roy

Commun Med (Lond)· June 2025

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Comparison of Local and Centrally Adjudicated Modified Rankin Scale Scores in the MOST Trial.
Adham Shawkat, Andrew D Barreto, Joseph P Broderick, Colin P Derdeyn, James C Grotta, Akash Roy

Stroke· May 2025

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KRAS mutation detection by liquid biopsy for pancreatic ductal adenocarcinoma.
Mahmoud Yousef, Abdelrahman Yousef, Mark W Hurd, Ashwathy Pillai, Saikat Chowdhury, Paul M Roy

J Hematol Oncol· April 2025

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Effects of Space Flight on Inflammasome Activation in the Brain of Mice.
Upal Roy, Roey Hadad, Angel A Rodriguez, Alen Saju, Deepa Roy

Cells· March 2025

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Safety and clinical outcomes of endovascular therapy versus medical management in late presentation of large ischemic stroke.
Adnan Mujanovic, Daniel Strbian, Jelle Demeestere, João Pedro Marto, Volker Puetz, Daniel Roy

Eur Stroke J· December 2024

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Treatment Outcomes and Definition Inconsistencies in High-Risk Unilateral Retinoblastoma.
Mattan Arazi, Alona Baum, Sandro Casavilca-Zambrano, Sandra Alarcon-Leon, Rosdali Diaz-Coronado, Soma Rani Roy

Am J Ophthalmol· December 2024

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Machine Learning-Based Perivascular Space Volumetry in Alzheimer Disease.
Katerina Deike, Andreas Decker, Paul Scheyhing, Julia Harten, Nadine Zimmermann, Nina Roy

Invest Radiol· September 2024

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Outcomes of Bridging Intravenous Thrombolysis Versus Endovascular Therapy Alone in Late-Window Acute Ischemic Stroke.
Jelle Demeestere, Muhammad M Qureshi, Lieselotte Vandewalle, Anke Wouters, Daniel Strbian, Daniel Roy

Stroke· July 2024

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The Safety of Outpatient Health Care : Review of Electronic Health Records.
David M Levine, Ania Syrowatka, Hojjat Salmasian, David M Shahian, Stuart Lipsitz, Christopher G Roy

Ann Intern Med· June 2024

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Noncontrast CT Selected Thrombectomy vs Medical Management for Late-Window Anterior Large Vessel Occlusion.
Thanh N Nguyen, Raul G Nogueira, Muhammad M Qureshi, Simon Nagel, Jean Raymond, Daniel Roy

Neurology· May 2024

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Endovascular Therapy in the Extended Time Window for Large Vessel Occlusion in Patients With Pre-Stroke Disability.
Kanta Tanaka, Hiroshi Yamagami, Muhammad M Qureshi, Kazutaka Uchida, James E Siegler, Daniel Roy

J Stroke· May 2024

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Sex Differences in Outcomes of Late-Window Endovascular Stroke Therapy.
Mohamad Abdalkader, Shen Ning, Muhammad M Qureshi, Diogo C Haussen, Daniel Strbian, Daniel Roy

Stroke· February 2024

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Multicenter, Phase 2, Randomized Controlled Study of the Efficacy and Safety of Etripamil Nasal Spray for the Acute Reduction of Rapid Ventricular Rate in Patients With Symptomatic Atrial Fibrillation (ReVeRA-201).
A John Camm, Jonathan P Piccini, Marco Alings, Paul Dorian, Gilbert Gosselin, Denis Roy

Circ Arrhythm Electrophysiol· December 2023

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Outcomes of robotic lobectomy for non-small cell lung cancer in a National Cancer Institute-Comprehensive Cancer Center National Cancer Database.
Jobelle J A R Baldonado, Samer A Naffouje, Sirish Parvathaneni, Esha Roy, Eric M Toloza

J Thorac Dis· October 2023

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Current clinical practices and challenges in molecular testing: a GOAL Consortium Hematopathology Working Group report.
Thomas D Lee, Dara L Aisner, Marjorie P David, Celeste C Eno, Jeffrey Gagan, Somak Roy

Blood Adv· August 2023

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A Pragmatic Randomized Trial Comparing Surgical Clipping and Endovascular Treatment of Unruptured Intracranial Aneurysms.
T E Darsaut, J M Findlay, M W Bojanowski, C Chalaala, D Iancu, D Roy

AJNR Am J Neuroradiol· June 2023

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