Publications by authors named "JA Gaspar"

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High-efficient serum-free differentiation of endothelial cells from human iPS cells.
Sarkawt Hamad, Daniel Derichsweiler, John Antonydas Gaspar, Konrad Brockmeier, Jürgen Hescheler

Stem Cell Res Ther· June 2022

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Suppression of angiotensin II-induced pathological changes in heart and kidney by the caveolin-1 scaffolding domain peptide.
Panneerselvam Chinnakkannu, Charles Reese, John Antony Gaspar, Saraswathi Panneerselvam, Dorea Pleasant-Jenkins

PLoS One· May 2019

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Depletion of Mageb16 induces differentiation of pluripotent stem cells predominantly into mesodermal derivatives.
John Antonydas Gaspar, Sureshkumar Perumal Srinivasan, Poornima Sureshkumar, Michael Xavier Doss, Jürgen Hescheler

Sci Rep· October 2017

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STRIP2 Is Indispensable for the Onset of Embryonic Stem Cell Differentiation.
Davood Sabour, Sureshkumar Perumal Srinivasan, Susan Rohani, Vilas Wagh, John Antonydas Gaspar

Mol Ther Methods Clin Dev· June 2017

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Definition of transcriptome-based indices for quantitative characterization of chemically disturbed stem cell development: introduction of the STOP-Tox and STOP-Tox tests.
Vaibhav Shinde, Lisa Hoelting, Sureshkumar Perumal Srinivasan, Johannes Meisig, Kesavan Meganathan, John Antonydas Gaspar

Arch Toxicol· February 2017

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MicroRNAs as early toxicity signatures of doxorubicin in human-induced pluripotent stem cell-derived cardiomyocytes.
Umesh Chaudhari, Harshal Nemade, John Antonydas Gaspar, Jürgen Hescheler, Jan G Hengstler

Arch Toxicol· December 2016

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Identification of genomic biomarkers for anthracycline-induced cardiotoxicity in human iPSC-derived cardiomyocytes: an in vitro repeated exposure toxicity approach for safety assessment.
Umesh Chaudhari, Harshal Nemade, Vilas Wagh, John Antonydas Gaspar, James K Ellis

Arch Toxicol· November 2016

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Corrigendum: Gene profiling of embryonic skeletal muscle lacking type I ryanodine receptor Ca(2+) release channel.
Dilyana Filipova, Anna M Walter, John A Gaspar, Anna Brunn, Nina F Linde

Sci Rep· April 2016

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Ascorbic Acid-Induced Cardiac Differentiation of Murine Pluripotent Stem Cells: Transcriptional Profiling and Effect of a Small Molecule Synergist of Wnt/β-Catenin Signaling Pathway.
Dina Ivanyuk, Galina Budash, Yunjie Zheng, John Antony Gaspar, Umesh Chaudhari

Cell Physiol Biochem· February 2016

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Gene profiling of embryonic skeletal muscle lacking type I ryanodine receptor Ca(2+) release channel.
Dilyana Filipova, Anna M Walter, John A Gaspar, Anna Brunn, Nina F Linde

Sci Rep· February 2016

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A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors.
Eugen Rempel, Lisa Hoelting, Tanja Waldmann, Nina V Balmer, Stefan Schildknecht, John Antony Das Gaspar

Arch Toxicol· September 2015

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Stem cells and differentiation--a synoptic review of patents granted since 2009.
Poornima Sureshkumar, Sureshkumar Perumal Srinivasan, Karthick Natarajan, John Antonydas Gaspar, Jürgen Hescheler

Expert Opin Ther Pat· June 2015

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Neuronal-specific deficiency of the splicing factor Tra2b causes apoptosis in neurogenic areas of the developing mouse brain.
Markus Storbeck, Kristina Hupperich, John Antonydas Gaspar, Kesavan Meganathan, Lilian Martínez Carrera

PLoS One· January 2015

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A comparative transcriptomic study on the effects of valproic acid on two different hESCs lines in a neural teratogenicity test system.
Silvia Colleoni, Cesare Galli, John Antony Gaspar, Kesavan Meganathan, Smita Jagtap

Toxicol Lett· November 2014

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Development of a pluripotent stem cell derived neuronal model to identify chemically induced pathway perturbations in relation to neurotoxicity: effects of CREB pathway inhibition.
Francesca Pistollato, Jochem Louisse, Bibiana Scelfo, Milena Mennecozzi, Benedetta Accordi, John Antonydas Gaspar

Toxicol Appl Pharmacol· October 2014

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Fam40b is required for lineage commitment of murine embryonic stem cells.
V Wagh, M X Doss, D Sabour, R Niemann, K Meganathan, J A Gaspar

Cell Death Dis· July 2014

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Unique metabolic features of stem cells, cardiomyocytes, and their progenitors.
John Antonydas Gaspar, Michael Xavier Doss, Jan Georg Hengstler, Cristina Cadenas, Jürgen Hescheler

Circ Res· April 2014

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Design principles of concentration-dependent transcriptome deviations in drug-exposed differentiating stem cells.
Tanja Waldmann, Eugen Rempel, Nina V Balmer, André König, Raivo Kolde, John Antonydas Gaspar

Chem Res Toxicol· March 2014

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Evidence for self-maintaining pluripotent murine stem cells in embryoid bodies.
Wael A Attia, Osama M Abd El Aziz, Dimitry Spitkovsky, John A Gaspar, Peter Dröge

Stem Cell Rev Rep· February 2014

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Proliferation and cilia dynamics in neural stem cells prospectively isolated from the SEZ.
Priti Khatri, Kirsten Obernier, Ina K Simeonova, Andrea Hellwig, Gabriele Hölzl-Wenig, John A Gaspar

Sci Rep· January 2014

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A liver-derived rat epithelial cell line from biliary origin acquires hepatic functions upon sequential exposure to hepatogenic growth factors and cytokines.
J De Kock, S Snykers, S Branson, S Jagtap, J A Gaspar

Curr Med Chem· August 2013

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Characterisation of a neural teratogenicity assay based on human ESCs differentiation following exposure to valproic acid.
S Colleoni, C Galli, J A Gaspar, K Meganathan, S Jagtap

Curr Med Chem· June 2013

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A tanscriptomics study to elucidate the toxicological mechanism of methylmercury chloride in a human stem cell based in vitro test.
K Vojnits, R Ensenat-Waser, J A Gaspar, K Meganathan, S Jagtap

Curr Med Chem· June 2013

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Identification of thalidomide-specific transcriptomics and proteomics signatures during differentiation of human embryonic stem cells.
Kesavan Meganathan, Smita Jagtap, Vilas Wagh, Johannes Winkler, John Antonydas Gaspar

PLoS One· February 2013

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Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approach.
Anne K Krug, Raivo Kolde, John A Gaspar, Eugen Rempel, Nina V Balmer

Arch Toxicol· January 2013

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