Publications by authors named "JR MacDonald"

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Antiplasmodial activity of tambjamines, dihydro-β-agarofurans and pyrroloazepines derived from Australian plant and marine species.
Jacinta R Macdonald, Gillian M Fisher, Sasha Hayes, Tina S Skinner-Adams, Rohan A Davis

Bioorg Med Chem Lett· December 2025

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Mirror effect of genomic deletions and duplications on cognitive ability across the human cerebral cortex.
Kuldeep Kumar, Sayeh Kazem, Guillaume Huguet, Worrawat Engchuan, Jakub Kopal, Jeffrey R MacDonald

bioRxiv· November 2025

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Determinants of pleiotropy and monotonic gene dosage responses across human traits.
Sayeh Kazem, Kuldeep Kumar, Guillaume Huguet, Josephine Mollon, Thomas Renne, Jeffrey R MacDonald

Res Sq· November 2025

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Vinyl-DNADetect Probes to Assess DNA Proliferation in Parasites using Inverse-Electron-Demand Diels-Alder Click Reactions.
Anne-Sophie C Braun, Gillian M Fisher, David H Hilko, Jacinta R Macdonald, Shilpa Thomas

ACS Chem Biol· October 2025

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Inner-mitochondrial membrane protein PfMPV17 is linked to P. falciparum in vitro resistance to the indoloquinolizidine alkaloid alstonine.
J R Macdonald, M S Arnold, M R Luth, D Cihalova, R J Quinn

J Antimicrob Chemother· July 2025

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Psychiatric disorders converge on common pathways but diverge in cellular context, spatial distribution, and directionality of genetic effects.
Worrawat Engchuan, Omar Shanta, Kuldeep Kumar, Jeffrey R MacDonald, Bhooma Thiruvahindrapuram

medRxiv· July 2025

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A cross-disorder analysis of CNVs finds novel loci and dose-dependent relationships of genes to psychiatric traits.
Omar Shanta, Marieke Klein, Molly Sacks, Jeffrey R MacDonald, Adam Maihofer

medRxiv· July 2025

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Gene dosage architecture across complex traits.
Sayeh Kazem, Kuldeep Kumar, Martineau Jean-Louis, Guillaume Huguet, Thomas Renne, Jeffrey R MacDonald

medRxiv· February 2025

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Comprehensive whole-genome sequence analyses provide insights into the genomic architecture of cerebral palsy.
Darcy L Fehlings, Mehdi Zarrei, Worrawat Engchuan, Neal Sondheimer, Bhooma Thiruvahindrapuram, Jeffrey R MacDonald

Nat Genet· April 2024

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Isolation and In Vitro and In Vivo Activity of Secondary Metabolites from Baker against Malaria Parasites.
Roktima Tamuli, Thanh Nguyen, Jacinta R Macdonald, Gregory K Pierens, Gillian M Fisher

J Nat Prod· December 2023

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Genetic variants in contribute to Autism Spectrum Disorder associated with the Xp22.11 locus.
Marcello Scala, Clarrisa A Bradley, Jennifer L Howe, Brett Trost, Nelson Bautista Salazar, Jeffrey R MacDonald

medRxiv· December 2023

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Gene copy number variation and pediatric mental health/neurodevelopment in a general population.
Mehdi Zarrei, Christie L Burton, Worrawat Engchuan, Edward J Higginbotham, John Wei, Jeffrey R MacDonald

Hum Mol Genet· July 2023

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Rare copy number variation in posttraumatic stress disorder.
Adam X Maihofer, Worrawat Engchuan, Guillaume Huguet, Marieke Klein, Jeffrey R MacDonald

Mol Psychiatry· December 2022

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Genomic architecture of autism from comprehensive whole-genome sequence annotation.
Brett Trost, Bhooma Thiruvahindrapuram, Ada J S Chan, Worrawat Engchuan, Edward J Higginbotham, Jeffrey R MacDonald

Cell· November 2022

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Genome-wide rare variant score associates with morphological subtypes of autism spectrum disorder.
Ada J S Chan, Worrawat Engchuan, Miriam S Reuter, Zhuozhi Wang, Bhooma Thiruvahindrapuram, Jeffrey R MacDonald

Nat Commun· October 2022

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Antiplasmodial activity of the natural product compounds alstonine and himbeline.
M S J Arnold, J R Macdonald, R J Quinn, T S Skinner-Adams, K T Andrews

Int J Parasitol Drugs Drug Resist· August 2021

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Ecdysteroids from the Stem Bark of Sweet (Lamiaceae; ex. Verbenaceae): A Geographically Variable African Medicinal Species.
Musa I Bunu, Derek T Ndinteh, Jacinta R Macdonald, Moses K Langat, Sani M Isyaka

Antibiotics (Basel)· August 2021

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A large data resource of genomic copy number variation across neurodevelopmental disorders.
Mehdi Zarrei, Christie L Burton, Worrawat Engchuan, Edwin J Young, Edward J Higginbotham, Jeffrey R MacDonald

NPJ Genom Med· October 2019

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Discovery of a rare and striking new pierid butterfly from Panama (Lepidoptera: Pieridae).
Shinichi Nakahara, John R Macdonald, Francisco Delgado, Pablo sebastiÁn PadrÓn

Zootaxa· December 2018

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De novo and rare inherited copy-number variations in the hemiplegic form of cerebral palsy.
Mehdi Zarrei, Darcy L Fehlings, Karizma Mawjee, Lauren Switzer, Bhooma Thiruvahindrapuram, Jeffrey R MacDonald

Genet Med· February 2018

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The Personal Genome Project Canada: findings from whole genome sequences of the inaugural 56 participants.
Miriam S Reuter, Susan Walker, Bhooma Thiruvahindrapuram, Joe Whitney, Iris Cohn, Jeffrey R MacDonald

CMAJ· February 2018

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Association of IMMP2L deletions with autism spectrum disorder: A trio family study and meta-analysis.
Yanqing Zhang, Yi Liu, Mehdi Zarrei, Winnie Tong, Rui Dong, Jeffrey R MacDonald

Am J Med Genet B Neuropsychiatr Genet· January 2018

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A Comprehensive Workflow for Read Depth-Based Identification of Copy-Number Variation from Whole-Genome Sequence Data.
Brett Trost, Susan Walker, Zhuozhi Wang, Bhooma Thiruvahindrapuram, Jeffrey R MacDonald

Am J Hum Genet· January 2018

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Whole genome sequencing resource identifies 18 new candidate genes for autism spectrum disorder.
Ryan K C Yuen, Daniele Merico, Matt Bookman, Jennifer L Howe, Bhooma Thiruvahindrapuram, Jeffrey R MacDonald

Nat Neurosci· April 2017

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