Publications by authors named "Jake Lin"

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Nature-derived microbiota exposure as a novel immunomodulatory approach.
Noora Nurminen, Jake Lin, Mira Grönroos, Riikka Puhakka, Lenka Kramna, Heli K Vari, Hanna Viskari, Sami Oikarinen, Marja Roslund, Anirudra Parajuli

Future Microbiol· June 2018

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Mouse strain-specific responses along the gut-brain axis upon fecal microbiota transplantation from children with autism.
Naika Prince, Lucia N Peralta Marzal, Léa Roussin, Magali Monnoye, Catherine Philippe, Jake Lin

Gut Microbes· December 2025

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Large-scale genome-wide analyses with proteomics integration reveal novel loci and biological insights into frailty.
Jonathan K L Mak, Chenxi Qin, Moritz Krüger, Anna Kuukka, , Jake Lin

Nat Aging· August 2025

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Exome-wide association study reveals 7 functional variants associated with ex-vivo drug response in acute myeloid leukemia patients.
Anil K Giri, Jake Lin, Konstantinos Kyriakidis, Garima Tripathi, Henrikki Almusa

BMC Med Genomics· April 2025

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Genetic evidence for efficacy of targeting IL-2, IL-6 and TYK2 signalling in the prevention of type 1 diabetes: a Mendelian randomisation study.
Tea E Heikkilä, Emilia K Kaiser, Jake Lin, Dipender Gill, Jaakko J Koskenniemi

Diabetologia· December 2024

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Exploring autism spectrum disorder and co-occurring trait associations to elucidate multivariate genetic mechanisms and insights.
Karoliina Salenius, Niina Väljä, Sini Thusberg, Francois Iris, Christine Ladd-Acosta, Jake Lin

BMC Psychiatry· December 2024

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Integration of Biomarker Polygenic Risk Score Improves Prediction of Coronary Heart Disease.
Jake Lin, Nina Mars, Yu Fu, Pietari Ripatti, Tuomo Kiiskinen

JACC Basic Transl Sci· December 2023

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Distinct transcriptomic profiles in children prior to the appearance of type 1 diabetes-linked islet autoantibodies and following enterovirus infection.
Jake Lin, Elaheh Moradi, Karoliina Salenius, Suvi Lehtipuro, Tomi Häkkinen, Sofia Randelin

Nat Commun· November 2023

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Unraveling the metabolic underpinnings of frailty using multicohort observational and Mendelian randomization analyses.
Jonathan K L Mak, Laura Kananen, Chenxi Qin, Ralf Kuja-Halkola, Bowen Tang, Jake Lin

Aging Cell· August 2023

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IDARE2-Simultaneous Visualisation of Multiomics Data in Cytoscape.
Thomas Pfau, Mafalda Galhardo, Jake Lin, Thomas Sauter

Metabolites· May 2021

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An expanded analysis framework for multivariate GWAS connects inflammatory biomarkers to functional variants and disease.
Sanni E Ruotsalainen, Juulia J Partanen, Anna Cichonska, Jake Lin, Christian Benner

Eur J Hum Genet· February 2021

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Genetic Adaptation of Coxsackievirus B1 during Persistent Infection in Pancreatic Cells.
Anni Honkimaa, Bryn Kimura, Amir-Babak Sioofy-Khojine, Jake Lin, Jutta Laiho

Microorganisms· November 2020

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Metagenomics of the faecal virome indicate a cumulative effect of enterovirus and gluten amount on the risk of coeliac disease autoimmunity in genetically at risk children: the TEDDY study.
Katri Lindfors, Jake Lin, Hye-Seung Lee, Heikki Hyöty, Matti Nykter

Gut· August 2020

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MetaPhat: Detecting and Decomposing Multivariate Associations From Univariate Genome-Wide Association Statistics.
Jake Lin, Rubina Tabassum, Samuli Ripatti, Matti Pirinen

Front Genet· May 2020

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Polygenic Hyperlipidemias and Coronary Artery Disease Risk.
Pietari Ripatti, Joel T Rämö, Nina J Mars, Yu Fu, Jake Lin, Aki S Havulinna

Circ Genom Precis Med· April 2020

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Data-driven characterization of molecular phenotypes across heterogeneous sample collections.
Juha Mehtonen, Petri Pölönen, Sergei Häyrynen, Olli Dufva, Jake Lin

Nucleic Acids Res· July 2019

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Hemap: An Interactive Online Resource for Characterizing Molecular Phenotypes across Hematologic Malignancies.
Petri Pölönen, Juha Mehtonen, Jake Lin, Thomas Liuksiala, Sergei Häyrynen, Caroline A Heckman

Cancer Res· May 2019

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Bioinformatics Assembling and Assessment of Novel Coxsackievirus B1 Genome.
Jake Lin, Bryn Y Kimura, Sami Oikarinen, Matti Nykter

Methods Mol Biol· April 2019

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Changes in the lung bacteriome in relation to antipseudomonal therapy in children with cystic fibrosis.
Lenka Kramná, Pavel Dřevínek, Jake Lin, Michal Kulich, Ondrej Cinek

Folia Microbiol (Praha)· March 2018

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Imbalance of bacteriome profiles within the Finnish Diabetes Prediction and Prevention study: Parallel use of 16S profiling and virome sequencing in stool samples from children with islet autoimmunity and matched controls.
Ondrej Cinek, Lenka Kramna, Jake Lin, Sami Oikarinen, Katerina Kolarova

Pediatr Diabetes· November 2017

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Vipie: web pipeline for parallel characterization of viral populations from multiple NGS samples.
Jake Lin, Lenka Kramna, Reija Autio, Heikki Hyöty, Matti Nykter

BMC Genomics· May 2017

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Systems genomics evaluation of the SH-SY5Y neuroblastoma cell line as a model for Parkinson's disease.
Abhimanyu Krishna, Maria Biryukov, Christophe Trefois, Paul M A Antony, Rene Hussong, Jake Lin, Dennis Linke, Rudi Balling

BMC Genomics· December 2014

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ChIP-seq profiling of the active chromatin marker H3K4me3 and PPARγ, CEBPα and LXR target genes in human SGBS adipocytes.
Mafalda Galhardo, Lasse Sinkkonen, Philipp Berninger, Jake Lin, Thomas Sauter

Genom Data· December 2014

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Transcriptomics profiling of human SGBS adipogenesis.
Mafalda Galhardo, Lasse Sinkkonen, Philipp Berninger, Jake Lin, Thomas Sauter

Genom Data· December 2014

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Community-integrated omics links dominance of a microbial generalist to fine-tuned resource usage.
Emilie E L Muller, Nicolás Pinel, Cédric C Laczny, Michael R Hoopmann, Shaman Narayanasamy, Jake Lin, Linda Wampach

Nat Commun· November 2014

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