Publications by authors named "Jan D Kuhlmann"

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Multi-compartment immune cell profiling highlights the prognostic relevance of CD127+ CD8+ T cells for patients with high-grade serous ovarian cancer.
Rebecca Rothe, Antje Tunger, Theresa Link, Xixi Lai, Jan Dominik Kuhlmann

Front Immunol· November 2025

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Methylstat sensitizes ovarian cancer cells to PARP-inhibition by targeting the histone demethylases JMJD1B/C.
Franziska Maria Schwarz, Daniel Martin Klotz, Ruming Yang, Melanie Brux, Frank Buchholz, Jan Dominik Kuhlmann

Cancer Gene Ther· March 2025

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Exploring evolutionary trajectories in ovarian cancer patients by longitudinal analysis of ctDNA.
Oliver Kutz, Stephan Drukewitz, Alexander Krüger, Daniela Aust, Doreen William, Jan Dominik Kuhlmann

Clin Chem Lab Med· September 2024

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Induction of circulating ABCB1 transcripts under platinum-based chemotherapy indicates poor prognosis and a bone micrometastatic phenotype in ovarian cancer patients.
Franziska Maria Schwarz, Jan Dominik Kuhlmann, Jorrin Kämpfer, Anna Klimova, Daniel Martin Klotz

Mol Cancer· August 2024

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Urinary-based detection of MSL, HE4 and CA125 as an additional dimension for predictive and prognostic modelling in ovarian cancer.
Franziska Maria Schwarz, Daniel Martin Klotz, Pauline Wimberger, Jan Dominik Kuhlmann

Front Oncol· July 2024

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A predictive and prognostic model for surgical outcome and prognosis in ovarian cancer computed by clinico-pathological and serological parameters (CA125, HE4, mesothelin).
Daniel Martin Klotz, Theresa Link, Pauline Wimberger, Jan Dominik Kuhlmann

Clin Chem Lab Med· February 2024

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RANK Expression as an Independent Predictor for Response to Neoadjuvant Chemotherapy in Luminal-Like Breast Cancer: A Translational Insight from the GeparX Trial.
Theresa Link, Jens-Uwe Blohmer, Wolfgang D Schmitt, Jan Dominik Kuhlmann, Marianne Just

Clin Cancer Res· November 2023

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Correction: Diagnostic Benefit of the Detection of Mitotic Figures in Endometriotic Lesions.
Michelle Wetzk, Nannette Grübling, Almuth Forberger, Jörg Klengel, Jan Dominik Kuhlmann

Geburtshilfe Frauenheilkd· August 2023

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Establishment and Molecular Characterization of an In Vitro Model for PARPi-Resistant Ovarian Cancer.
Daniel Martin Klotz, Franziska Maria Schwarz, Anna Dubrovska, Kati Schuster, Mirko Theis, Jan Dominik Kuhlmann

Cancers (Basel)· July 2023

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The effect of denosumab on disseminated tumor cells (DTCs) of breast cancer patients with neoadjuvant treatment: a GeparX translational substudy.
Pauline Wimberger, Jens-Uwe Blohmer, Petra Krabisch, Theresa Link, Marianne Just, Jan Dominik Kuhlmann

Breast Cancer Res· March 2023

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Mesenchymal stromal cell-associated migrasomes: a new source of chemoattractant for cells of hematopoietic origin.
Ilker A Deniz, Jana Karbanová, Manja Wobus, Martin Bornhäuser, Pauline Wimberger, Jan Dominik Kuhlmann

Cell Commun Signal· February 2023

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Palbociclib impairs the proliferative capacity of activated T cells while retaining their cytotoxic efficacy.
Claudia Arndt, Antje Tunger, Rebekka Wehner, Rebecca Rothe, Eleni Kourtellari, Jan Dominik Kuhlmann

Front Pharmacol· February 2023

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Bevacizumab May Differentially Improve Prognosis of Advanced Ovarian Cancer Patients with Low Expression of VEGF-A165b, an Antiangiogenic VEGF-A Splice Variant.
Pauline Wimberger, Mara Julia Gerber, Jacobus Pfisterer, Kati Erdmann, Susanne Füssel, Jan Dominik Kuhlmann

Clin Cancer Res· November 2022

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Clinical impact of soluble Neuropilin-1 in ovarian cancer patients and its association with its circulating ligands of the HGF/c-MET axis.
Daniel Martin Klotz, Jan Dominik Kuhlmann, Theresa Link, Maren Goeckenjan, Lorenz C Hofbauer

Front Oncol· October 2022

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Evaluation of circulating Dickkopf-1 as a prognostic biomarker in ovarian cancer patients.
Daniel Martin Klotz, Theresa Link, Maren Goeckenjan, Pauline Wimberger, Anna R Poetsch, Jan Dominik Kuhlmann

Clin Chem Lab Med· January 2022

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Diagnostic Benefit of the Detection of Mitotic Figures in Endometriotic Lesions.
Michelle Wetzk, Nannette Grübling, Almuth Forberger, Jörg Klengel, Jan Dominik Kuhlmann

Geburtshilfe Frauenheilkd· January 2022

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Promoter Polymorphisms Are Independent Predictors of Survival in Patients with Triple Negative Breast Cancer.
Hagen Sjard Bachmann, Dominik Jung, Theresa Link, Anna Arnold, Eva Kantelhardt, Jan Dominik Kuhlmann

Cancers (Basel)· January 2022

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Decoding Single Cell Morphology in Osteotropic Breast Cancer Cells for Dissecting Their Migratory, Molecular and Biophysical Heterogeneity.
Lila Bemmerlein, Ilker A Deniz, Jana Karbanová, Angela Jacobi, Stephan Drukewitz, Jan Dominik Kuhlmann

Cancers (Basel)· January 2022

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Prognostic relevance of longitudinal HGF levels in serum of patients with ovarian cancer.
Daniel Martin Klotz, Theresa Link, Pauline Wimberger, Jan Dominik Kuhlmann

Mol Oncol· December 2021

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Reorganization of the osteocyte lacuno-canalicular network characteristics in tumor sites of an immunocompetent murine model of osteotropic cancers.
Haniyeh Hemmatian, Stefanie Conrad, Giulia Furesi, Kathrin Mletzko, Johannes Krug, Jan Dominik Kuhlmann

Bone· November 2021

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ADAM17-A Potential Blood-Based Biomarker for Detection of Early-Stage Ovarian Cancer.
Christoph Rogmans, Jan Dominik Kuhlmann, Gerrit Hugendieck, Theresa Link, Norbert Arnold

Cancers (Basel)· November 2021

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Diminished PLK2 Induces Cardiac Fibrosis and Promotes Atrial Fibrillation.
Stephan R Künzel, Maximilian Hoffmann, Silvio Weber, Karolina Künzel, Susanne Kämmerer, Jan Dominik Kuhlmann

Circ Res· October 2021

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The levels of soluble cMET ectodomain in the blood of patients with ovarian cancer are an independent prognostic biomarker.
Daniel Martin Klotz, Theresa Link, Maren Goeckenjan, Pauline Wimberger, Jan Dominik Kuhlmann

Mol Oncol· September 2021

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Image-Based Identification and Genomic Analysis of Single Circulating Tumor Cells in High Grade Serous Ovarian Cancer Patients.
Carolin Salmon, Janina Levermann, Rui P L Neves, Sven-Thorsten Liffers, Jan Dominik Kuhlmann

Cancers (Basel)· July 2021

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The effect of the triazene compound CT913 on ovarian cancer cells in vitro and its synergistic interaction with the PARP-inhibitor olaparib.
Catharina Wichmann, Daniel Martin Klotz, Hans-Joachim Zeiler, Ralf Axel Hilger, Konrad Grützmann, Jan Dominik Kuhlmann

Gynecol Oncol· December 2020

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