Publications by authors named "Jan Melenhorst"

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Correction: NT-I7, a novel long-acting interleukin-7, promotes anti-PD-1 efficacy in an autologous humanized melanoma model.
Yee Peng Phoon, Alexandra A Wolfarth, Pauline Funchain, Jennifer S Ko, Donghoon Choi, Jan J Melenhorst

Sci Rep· December 2025

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NT-I7, a novel long-acting interleukin-7, promotes anti-PD-1 efficacy in an autologous humanized melanoma model.
Yee Peng Phoon, Alexandra A Wolfarth, Pauline Funchain, Jennifer S Ko, Donghoon Choi, Jan J Melenhorst

Sci Rep· October 2025

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MCL1 may not mediate chemoresistance.
Kylin A Emhoff, Kunho Chung, Dongmei Zhang, Belinda Willard, Timothy Chan, Jan Joseph Melenhorst

bioRxiv· August 2025

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Optimizing Chimeric Antigen Receptor T-Cell Therapy for Mantle Cell Lymphoma.
Arun Kumar Arunachalam, Cassandra K Gilmour, Jan Joseph Melenhorst

J Clin Oncol· July 2025

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Long-term safety of lentiviral or gammaretroviral gene-modified T cell therapies.
Julie K Jadlowsky, Elizabeth O Hexner, Amy Marshall, Stephan A Grupp, Noelle V Frey, Jan Joseph Melenhorst

Nat Med· April 2025

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Chimeric antigen receptor T-cell therapy for haematological malignancies: Insights from fundamental and translational research to bedside practice.
Céline Grégoire, Beatriz Coutinho de Oliveira, Paolo F Caimi, Jo Caers, Jan Joseph Melenhorst

Br J Haematol· November 2024

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Advancing CAR T-cell therapies: Preclinical insights and clinical translation for hematological malignancies.
Arun K Arunachalam, Céline Grégoire, Beatriz Coutinho de Oliveira, Jan Joseph Melenhorst

Blood Rev· November 2024

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TET2 regulates early and late transitions in exhausted CD8 T cell differentiation and limits CAR T cell function.
Alexander J Dimitri, Amy E Baxter, Gregory M Chen, Caitlin R Hopkins, Geoffrey T Rouin, Jan Joseph Melenhorst

Sci Adv· November 2024

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Advancing Cholangiocarcinoma Care: Insights and Innovations in T Cell Therapy.
Neda Dadgar, Arun K Arunachalam, Hanna Hong, Yee Peng Phoon, Jorge E Arpi-Palacios, Jan Joseph Melenhorst

Cancers (Basel)· September 2024

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Allogeneic CAR T Cells: Complex Cellular Therapy Designs Test the Limits of Our Preclinical Models.
Paolo F Caimi, Jan Joseph Melenhorst

Cancer Immunol Res· April 2024

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Autologous human preclinical modeling of melanoma interpatient clinical responses to immunotherapeutics.
Yee Peng Phoon, Jared E Lopes, Lukas W Pfannenstiel, Claudia Marcela Diaz-Montero, Ye F Tian, Jan Joseph Melenhorst

J Immunother Cancer· April 2024

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Positively charged patches: tonic for CAR fitness.
Meraj H Khan, Jan Joseph Melenhorst

Cell Res· May 2023

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Spatial immunosampling of MRI-defined glioblastoma regions reveals immunologic fingerprint of non-contrast enhancing, infiltrative tumor margins.
Matthew M Grabowski, Dionysios C Watson, Kunho Chung, Juyeun Lee, Defne Bayik, Jan Joseph Melenhorst

medRxiv· March 2023

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Challenges and opportunities of CAR T-cell therapies for CLL.
Ziran Zhao, Céline Grégoire, Beatriz Oliveira, Kunho Chung, Jan Joseph Melenhorst

Semin Hematol· January 2023

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Adaptable Leukemia Cells Resisting CAR T-cell Attack via B-cell Activation.
Ziran Zhao, Jan Joseph Melenhorst

Cancer Immunol Res· September 2022

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B cell targeting in CAR T cell therapy: Side effect or driver of CAR T cell function?
Gregory M Chen, Jan Joseph Melenhorst, Kai Tan

Sci Transl Med· June 2022

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Temperature Trajectory Sub-phenotypes and the Immuno-Inflammatory Response in Pediatric Sepsis.
Nadir Yehya, Julie C Fitzgerald, Katie Hayes, Donglan Zhang, Jenny Bush, Jan Joseph Melenhorst

Shock· May 2022

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PD1 Expression in EGFRvIII-Directed CAR T Cell Infusion Product for Glioblastoma Is Associated with Clinical Response.
Oliver Y Tang, Lifeng Tian, Todd Yoder, Rong Xu, Irina Kulikovskaya, Jan Joseph Melenhorst

Front Immunol· May 2022

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STAT3 Role in T-Cell Memory Formation.
Yaroslav Kaminskiy, Jan Joseph Melenhorst

Int J Mol Sci· March 2022

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Cancer stem cells: advances in biology and clinical translation-a Keystone Symposia report.
Jennifer Cable, Duanqing Pei, Lola M Reid, Xin Wei Wang, Sonam Bhatia, Jan Joseph Melenhorst

Ann N Y Acad Sci· December 2021

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Improving and Maintaining Responses in Pediatric B-Cell Acute Lymphoblastic Leukemia Chimeric Antigen Receptor-T Cell Therapy.
Rahul Arya, David M Barrett, Stephan A Grupp, Jan Joseph Melenhorst

Cancer J· September 2021

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Case Report: Prolonged Survival Following EGFRvIII CAR T Cell Treatment for Recurrent Glioblastoma.
Joseph S Durgin, Fraser Henderson, MacLean P Nasrallah, Suyash Mohan, Sumei Wang, Jan Joseph Melenhorst

Front Oncol· May 2021

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Endothelial Biomarkers Are Associated With Indirect Lung Injury in Sepsis-Associated Pediatric Acute Respiratory Distress Syndrome.
Jane E Whitney, Rui Feng, Natalka Koterba, Fang Chen, Jenny Bush, Jan Joseph Melenhorst

Crit Care Explor· December 2020

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Long-Term Outcomes From a Randomized Dose Optimization Study of Chimeric Antigen Receptor Modified T Cells in Relapsed Chronic Lymphocytic Leukemia.
Noelle V Frey, Saar Gill, Elizabeth O Hexner, Stephen Schuster, Sunita Nasta, Jan Joseph Melenhorst

J Clin Oncol· September 2020

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Systemic Endothelial Activation Is Associated With Early Acute Respiratory Distress Syndrome in Children With Extrapulmonary Sepsis.
Jane E Whitney, Binqing Zhang, Natalka Koterba, Fang Chen, Jenny Bush, Jan Joseph Melenhorst

Crit Care Med· March 2020

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