Publications by authors named "Janet M Lord"

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Multisystem physiological perspective of human frailty and its modulation by physical activity.
Joseph A Taylor, Paul L Greenhaff, David B Bartlett, Thomas A Jackson, Niharika A Duggal, Janet M Lord

Physiol Rev· April 2023

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Ten weeks of high-intensity interval walk training is associated with reduced disease activity and improved innate immune function in older adults with rheumatoid arthritis: a pilot study.
David B Bartlett, Leslie H Willis, Cris A Slentz, Andrew Hoselton, Leslie Kelly, Janet L Huebner, Virginia B Kraus, Jennifer Moss, Michael J Muehlbauer, Guillaume Spielmann

June 2018

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Major features of immunesenescence, including reduced thymic output, are ameliorated by high levels of physical activity in adulthood.
Niharika Arora Duggal, Ross D Pollock, Norman R Lazarus, Stephen Harridge, Janet M Lord

Aging Cell· April 2018

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Specific features of immune ageing are detected in the earliest stages in rheumatoid arthritis development.
Karim Raza, Archana Sharma-Oates, Leonid Padyukov, Annette H M van der Helm-van Mil, Arthur G Pratt, Janet M Lord

EBioMedicine· September 2025

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Ethnicity-specific patterns of epigenetic age acceleration in rheumatoid arthritis.
Archana Sharma-Oates, Niall Dunne, Karim Raza, Leonid Padyukov, Natalie Rivera, Janet M Lord

Geroscience· June 2025

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Accelerated epigenetic ageing after burn injury.
Jack Sullivan, Thomas Nicholson, Jon Hazeldine, Naiem Moiemen, Janet M Lord

Geroscience· June 2025

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Day One Cell-Free DNA Levels as an Objective Prognostic Marker of Mortality in Major Burns Patients.
Sebastian Tullie, Ali Asiri, Animesh Acharjee, Naiem S Moiemen, Janet M Lord

Cells· June 2025

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Physical Activity Modifies the Metabolic Profile of CD4 and CD8 T-Cell Subtypes at Rest and Upon Activation in Older Adults.
Jon Hazeldine, Edward Withnall, Alba Llibre, Niharika A Duggal, Janet M Lord

Aging Cell· May 2025

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Major Traumatic Injury and Exposure to Mitochondrial-Derived Damage-Associated Molecular Patterns Promotes Neutrophil Survival Accompanied by Stabilisation of the Anti-Apoptotic Protein Mcl-1.
Thomas Nicholson, Michael Macleod, Antonio Belli, Janet M Lord, Jon Hazeldine

Cells· May 2025

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A novel framework to build saliva-based DNA methylation biomarkers: Quantifying systemic chronic inflammation as a case study.
Lisa J Schmunk, Toby P Call, Daniel L McCartney, Hira Javaid, Waylon J Hastings, Janet M Lord

Aging Cell· April 2025

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Time of day of vaccination does not influence antibody responses to pneumococcal and annual influenza vaccination in a cohort of healthy older adults.
Siân E Faustini, Claire Backhouse, Niharika A Duggal, Kai-Michael Toellner, Ruth Harvey, Janet M Lord

Vaccine· March 2025

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The effects of ultra-selective beta1-antagonism on the metabolic and cytokine profile in septic shock patients receiving noradrenaline: a sub-investigation from the STRESS-L Randomised Study.
Jarrod L Thomas, Kirsty C McGee, Anower Hossain, Gavin D Perkins, Anthony C Gordon, Janet M Lord

Intensive Care Med Exp· January 2025

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Impact of Senescent Cell-Derived Extracellular Vesicles on Innate Immune Cell Function.
Yung-Yi Chen, Jack Sullivan, Shaun Hanley, Joshua Price, Mohammad A Tariq, Janet M Lord

Adv Biol (Weinh)· December 2024

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The impact of trauma relevant concentrations of prostaglandin E on the anti-microbial activity of the innate immune system.
Thomas Nicholson, Antonio Belli, Janet M Lord, Jon Hazeldine

Front Immunol· November 2024

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A combination nutritional supplement reduces DNA methylation age only in older adults with a raised epigenetic age.
Kirsty C McGee, Jack Sullivan, Jon Hazeldine, Lisa J Schmunk, Daniel E Martin-Herranz, Janet M Lord

Geroscience· October 2024

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Predictors of death without prior appropriate therapy in ICD recipients: the comorbidities, frailty and functional status (COMFFORT study).
David G Wilson, Archana Sharma-Oates, James Sheldon, Daniel F Power, Janet M Lord

Open Heart· October 2024

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1-year health outcomes associated with systemic corticosteroids for COVID-19: a longitudinal cohort study.
Olivia C Leavy, Richard J Russell, Ewen M Harrison, Nazir I Lone, Steven Kerr, Janet M Lord

ERJ Open Res· September 2024

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DYNamic Assessment of Multi-Organ level dysfunction in patients recovering from COVID-19: DYNAMO COVID-19.
Ayushman Gupta, Rosemary Nicholas, Jordan J McGing, Aline V Nixon, Joanne E Mallinson, Janet M Lord

Exp Physiol· August 2024

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Higher risk of upper respiratory tract infection post marathon running: when physical exercise becomes a threat to the immune system.
Amanda Veiga Sardeli, Rafaela Bertini de Araujo, Jeffrey A Woods, Janet M Lord, Mara Patrícia Traina Chacon-Mikahil

Exerc Immunol Rev· August 2024

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Severe thermal and major traumatic injury results in elevated plasma concentrations of total heme that are associated with poor clinical outcomes and systemic immune suppression.
Sebastian Tullie, Thomas Nicholson, Jonathan R B Bishop, Kirsty C McGee, Ali Asiri, Janet M Lord

Front Immunol· July 2024

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Accelerated aging of skeletal muscle and the immune system in patients with chronic liver disease.
Thomas Nicholson, Amritpal Dhaliwal, Jonathan I Quinlan, Sophie L Allen, Felicity R Williams, Janet M Lord

Exp Mol Med· July 2024

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Senescent cell-derived extracellular vesicles as potential mediators of innate immunosenescence and inflammaging.
Shaun Hanley, Yung-Yi Chen, Jon Hazeldine, Janet M Lord

Exp Gerontol· March 2024

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Duke Activity Status Index and Liver Frailty Index predict mortality in ambulatory patients with advanced chronic liver disease: A prospective, observational study.
Felicity R Williams, Jonathan Quinlan, Alice Freer, Breanna Morrison, Alice Sitch, Janet M Lord

Aliment Pharmacol Ther· February 2024

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Influence of scar age, laser type and laser treatment intervals on paediatric burn scars: a systematic review and meta-analysis.
Yangmyung Ma, Sabrina P Barnes, Yung-Yi Chen, Naiem Moiemen, Janet M Lord

Burns Trauma· February 2024

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Relaxation of mitochondrial hyperfusion in the diabetic retina via N6-furfuryladenosine confers neuroprotection regardless of glycaemic status.
Aidan Anderson, Nada Alfahad, Dulani Wimalachandra, Kaouthar Bouzinab, Paula Rudzinska, Janet M Lord

Nat Commun· February 2024

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Association of Epigenetic Age and Outcome in Critically Ill Patients.
Archana Sharma-Oates, Jack Sullivan, Daniel Pestana, Claudia C Dos Santos, Alexandra Binnie, Janet M Lord

Crit Care Explor· February 2024

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Cohort Profile: Post-Hospitalisation COVID-19 (PHOSP-COVID) study.
Omer Elneima, Hamish J C McAuley, Olivia C Leavy, James D Chalmers, Alex Horsley, Janet M Lord

Int J Epidemiol· February 2024

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Accelarated immune ageing is associated with COVID-19 disease severity.
Janet M Lord, Tonny Veenith, Jack Sullivan, Archana Sharma-Oates, Alex G Richter

Immun Ageing· January 2024

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