Publications by authors named "Jay Hooper"

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CCHFV-M based DNA vaccine is highly immunogenic in multiple species and protects against challenge in cynomolgus macaques.
John J Suschak, Collin J Fitzpatrick, Charles J Shoemaker, Joshua D Shamblin, Lauren E White, Jay W Hooper

Antiviral Res· November 2025

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Immune responses following DNA vaccination by needle-free injection against hemolysin co-regulated protein 1.
Michael L Davies, Sergei S Biryukov, Christopher P Klimko, Jennifer L Dankmeyer, Nathaniel O Rill, Jay W Hooper

Front Immunol· July 2025

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Ebola virus vaccination elicits Ebola virus-specific immune responses without substantial cross-reactivity to other filoviruses.
Thembi Mdluli, Suzanne Wollen-Roberts, Mélanie Merbah, Bradley Beckman, Yifan Li, Jay W Hooper

Sci Transl Med· April 2025

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rVSVΔG-ZEBOV-GP Vaccine Is Highly Immunogenic and Efficacious Across a Wide Dose Range in a Nonhuman Primate EBOV Challenge Model.
Amy C Shurtleff, John C Trefry, Sheri Dubey, Melek M E Sunay, Kenneth Liu, Jay W Hooper

Viruses· February 2025

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Mpox mRNA-1769 vaccine inhibits orthopoxvirus replication at intranasal, intrarectal, and cutaneous sites of inoculation.
Catherine A Cotter, Maxinne A Ignacio, Jeffrey L Americo, Patricia L Earl, Eric M Mucker, Jay W Hooper

NPJ Vaccines· December 2024

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Phase 1 clinical trial of Hantaan and Puumala virus DNA vaccines delivered by needle-free injection.
Jay W Hooper, Steven A Kwilas, Matthew Josleyn, Sarah Norris, Jack N Hutter

NPJ Vaccines· November 2024

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Safety and Immunogenicity of Accelerated Heterologous 2-Dose Ebola Vaccine Regimens in Adults With and Without HIV in Africa.
Betty Mwesigwa, Fredrick Sawe, Janet Oyieko, Joel Mwakisisile, Edna Viegas, Jay W Hooper

Clin Infect Dis· October 2024

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Comparison of protection against mpox following mRNA or modified vaccinia Ankara vaccination in nonhuman primates.
Eric M Mucker, Alec W Freyn, Sandra L Bixler, Deniz Cizmeci, Caroline Atyeo, Jay W Hooper

Cell· October 2024

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Preclinical evaluation of a fully human, quadrivalent-hantavirus polyclonal antibody derived from a non-human source.
Rebecca L Brocato, Hua Wu, Steven A Kwilas, Lucia M Principe, Matthew Josleyn, Jay W Hooper

mBio· October 2024

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Mpox mRNA-1769 Vaccine Inhibits Orthopoxvirus Replication at Intranasal, Intrarectal, and Cutaneous Sites of Inoculation.
Catherine A Cotter, Maxinne A Ignacio, Jeffrey L Americo, Patricia L Earl, Eric M Mucker, Jay W Hooper

bioRxiv· September 2024

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Glycoprotein-Specific Polyclonal Antibodies Targeting Machupo Virus Protect Guinea Pigs against Lethal Infection.
Joseph W Golden, Steven A Kwilas, Jay W Hooper

Vaccines (Basel)· June 2024

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Safety and Immunogenicity of an Accelerated Ebola Vaccination Schedule in People with and without Human Immunodeficiency Virus: A Randomized Clinical Trial.
Julie A Ake, Kristopher Paolino, Jack N Hutter, Susan Biggs Cicatelli, Leigh Anne Eller, Jay W Hooper

Vaccines (Basel)· May 2024

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Safety and Immunogenicity of an Andes Virus DNA Vaccine by Needle-Free Injection: A Randomized, Controlled Phase 1 Study.
Grant C Paulsen, Robert Frenck, Kay M Tomashek, Rodolfo M Alarcon, Elizabeth Hensel, Jay W Hooper

J Infect Dis· January 2024

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Antibody responses to recombinant vesicular stomatitis virus-Zaire Ebolavirus vaccination for Ebola virus disease across doses and continents: 5-year durability.
Angela Huttner, Selidji Todagbe Agnandji, Olivier Engler, Jay W Hooper, Steve Kwilas

Clin Microbiol Infect· December 2023

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An mpox virus mRNA-lipid nanoparticle vaccine confers protection against lethal orthopoxviral challenge.
Alec W Freyn, Caroline Atyeo, Patricia L Earl, Jeffrey L Americo, Gwo-Yu Chuang, Jay W Hooper

Sci Transl Med· October 2023

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Development of a specific MPXV antigen detection immunodiagnostic assay.
Ian Davis, Jackie M Payne, Victoria L Olguin, Madison P Sanders, Tamara Clements, Jay W Hooper

Front Microbiol· September 2023

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Humoral immunogenicity of a Coronavirus Disease 2019 (COVID-19) DNA vaccine in rhesus macaques (Macaca mulatta) delivered using needle-free jet injection.
Alexandra Jay, Steven A Kwilas, Matthew Josleyn, Keersten Ricks, Jay W Hooper

PLoS One· June 2023

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Evaluation of a panel of therapeutic antibody clinical candidates for efficacy against SARS-CoV-2 in Syrian hamsters.
Yu Cong, Eric M Mucker, Donna L Perry, Saurabh Dixit, Erin Kollins, Jay W Hooper

Antiviral Res· May 2023

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Antigenic mapping and functional characterization of human New World hantavirus neutralizing antibodies.
Taylor B Engdahl, Elad Binshtein, Rebecca L Brocato, Natalia A Kuzmina, Lucia M Principe, Jay W Hooper

Elife· March 2023

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Development of a rapid image-based high-content imaging screening assay to evaluate therapeutic antibodies against the monkeypox virus.
Krishna P Kota, Natasza E Ziółkowska, Jiayi Wei, Junzhong Peng, David Ordonez, Jay W Hooper

Antiviral Res· February 2023

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Improved DNA Vaccine Delivery with Needle-Free Injection Systems.
Carmen Ledesma-Feliciano, Ros Chapman, Jay W Hooper, Kira Elma, Darin Zehrung

Vaccines (Basel)· January 2023

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Preclinical characterization of amubarvimab and romlusevimab, a pair of non-competing neutralizing monoclonal antibody cocktail, against SARS-CoV-2.
Yun Ji, Qi Zhang, Lin Cheng, Jiwan Ge, Ruoke Wang, Jay W Hooper

Front Immunol· October 2022

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SARS-CoV-2 Doggybone DNA Vaccine Produces Cross-Variant Neutralizing Antibodies and Is Protective in a COVID-19 Animal Model.
Eric M Mucker, Rebecca L Brocato, Lucia M Principe, Robert K Kim, Xiankun Zeng, Jay W Hooper

Vaccines (Basel)· July 2022

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Lipid nanoparticle delivery of unmodified mRNAs encoding multiple monoclonal antibodies targeting poxviruses in rabbits.
Eric M Mucker, Carolin Thiele-Suess, Patrick Baumhof, Jay W Hooper

Mol Ther Nucleic Acids· June 2022

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Exposure Route Influences Disease Severity in the COVID-19 Cynomolgus Macaque Model.
Sandra L Bixler, Christopher P Stefan, Alexandra N Jay, Franco D Rossi, Keersten M Ricks, Jay W Hooper

Viruses· May 2022

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