Publications by authors named "Jeanne Hardy"

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Inhibition of Zika Virus Protease by Modulating NS2B-NS3 Interactions.
Andrew J Smith, Muhammad Arslan Rahat, Leonardo J Scaramozza, Stephen J Eyles, Jeanne A Hardy

Biochemistry· January 2026

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Orthogonal RNA-regulated destabilization domains for three-color RNA imaging with minimal RNA perturbation.
Tien G Pham, Omoyemi Ajayi, Jiaze He, Irina Sagarbarria, Jeanne A Hardy

Nat Methods· December 2025

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An NMR sample preparation case study: Considerations for the self-destructive protease caspase-6.
Nathanael J Kuzio, Marco Tonelli, Jasna Fejzo, Jeanne A Hardy

PLoS One· November 2025

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A robust fluorogenic substrate for chikungunya virus protease (nsP2) activity.
Sparsh Makhaik, Wioletta Rut, Shruti Choudhary, Tulsi Upadhyay, Chenzhou Hao, Jeanne A Hardy

Protein Sci· March 2025

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A Robust Fluorogenic Substrate for Chikungunya Virus Protease (nsP2) Activity.
Sparsh Makhaik, Wioletta Rut, Shruti Choudhary, Tulsi Upadhyay, Chenzhou Hao, Jeanne A Hardy

bioRxiv· February 2025

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FRET Probes for Detection of Both Active and Inactive Zika Virus Protease.
Kristalle G Cruz, Kevin Alexander, Sparsh Makhaik, Jeanne A Hardy

Biochemistry· December 2024

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A Non-Active-Site Inhibitor with Selectivity for Zika Virus NS2B-NS3 Protease.
Kristalle G Cruz, Maureen Hill Eron, Sparsh Makhaik, Sergey Savinov, Jeanne A Hardy

ACS Infect Dis· February 2024

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Colorimetric Cotton Swab for Viral Protease Detection.
Ranit Dutta, Sparsh Makhaik, Peiyao Zhao, Kristalle G Cruz, Kwang-Won Park, Jeanne A Hardy

Anal Chem· September 2022

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Deorphanizing Caspase-3 and Caspase-9 Substrates In and Out of Apoptosis with Deep Substrate Profiling.
Luam E Araya, Ishankumar V Soni, Jeanne A Hardy, Olivier Julien

ACS Chem Biol· November 2021

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Intracellular delivery of protein drugs with an autonomously lysing bacterial system reduces tumor growth and metastases.
Vishnu Raman, Nele Van Dessel, Christopher L Hall, Victoria E Wetherby, Samantha A Whitney, Jeanne A Hardy

Nat Commun· October 2021

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Caspase-9 Activation of Procaspase-3 but Not Procaspase-6 Is Based on the Local Context of Cleavage Site Motifs and on Sequence.
Ishankumar V Soni, Jeanne A Hardy

Biochemistry· September 2021

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Exogenous Introduction of Initiator and Executioner Caspases Results in Different Apoptotic Outcomes.
Francesca Anson, S Thayumanavan, Jeanne A Hardy

JACS Au· August 2021

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Evaluating Endosomal Escape of Caspase-3-Containing Nanomaterials Using Split GFP.
Francesca Anson, Bin Liu, Pintu Kanjilal, Peidong Wu, Jeanne A Hardy

Biomacromolecules· March 2021

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Tracking exogenous intracellular casp-3 using split GFP.
Francesca Anson, Pintu Kanjilal, S Thayumanavan, Jeanne A Hardy

Protein Sci· February 2021

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A fluorescence-activatable reporter of flavivirus NS2B-NS3 protease activity enables live imaging of infection in single cells and viral plaques.
Jorge L Arias-Arias, Derek J MacPherson, Maureen E Hill, Jeanne A Hardy, Rodrigo Mora-Rodríguez

J Biol Chem· February 2020

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Chemoproteomics Using Nucleotide Acyl Phosphates Reveals an ATP Binding Site at the Dimer Interface of Procaspase-6.
Eric S Okerberg, Kevin B Dagbay, Jennifer L Green, Ishankumar Soni, Arwin Aban, Jeanne A Hardy

Biochemistry· December 2019

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A Nanopore Approach for Analysis of Caspase-7 Activity in Cell Lysates.
Bach Pham, Scott J Eron, Maureen E Hill, Xin Li, Monifa A Fahie, Jeanne A Hardy

Biophys J· September 2019

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Cysteine Disulfide Traps Reveal Distinct Conformational Ensembles in Dengue Virus NS2B-NS3 Protease.
Maureen E Hill, Muslum Yildiz, Jeanne A Hardy

Biochemistry· February 2019

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Tri-arginine exosite patch of caspase-6 recruits substrates for hydrolysis.
Derek J MacPherson, Caitlyn L Mills, Mary Jo Ondrechen, Jeanne A Hardy

J Biol Chem· January 2019

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The Unique Cofactor Region of Zika Virus NS2B-NS3 Protease Facilitates Cleavage of Key Host Proteins.
Maureen E Hill, Anil Kumar, James A Wells, Tom C Hobman, Olivier Julien, Jeanne A Hardy

ACS Chem Biol· September 2018

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Fighting Kinase Drug Resistance with Caspase Activators.
Jeanne A Hardy

Cell Chem Biol· August 2018

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Phosphorylation by protein kinase A disassembles the caspase-9 core.
Banyuhay P Serrano, Jeanne A Hardy

Cell Death Differ· June 2018

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Multiple Mechanisms of Zinc-Mediated Inhibition for the Apoptotic Caspases-3, -6, -7, and -8.
Scott J Eron, Derek J MacPherson, Kevin B Dagbay, Jeanne A Hardy

ACS Chem Biol· May 2018

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Caspase-9 CARD : core domain interactions require a properly formed active site.
Kristen L Huber, Banyuhay P Serrano, Jeanne A Hardy

Biochem J· March 2018

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Rare human Caspase-6-R65W and Caspase-6-G66R variants identify a novel regulatory region of Caspase-6 activity.
Agne Tubeleviciute-Aydin, Libin Zhou, Gyanesh Sharma, Ishankumar V Soni, Sergey N Savinov, Jeanne A Hardy

Sci Rep· March 2018

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