Publications by authors named "Jennifer Atkinson"

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Identification and Credentialing of Patient Derived Xenograft Models of Invasive Lobular Breast Carcinoma using Multi-omics and Histopathology assessment.
Jagmohan Hooda, Jennifer M Atkinson, Osama Shiraz Shah, Megan Yates, Daniel D Brown

bioRxiv· August 2025

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p95HER2, a truncated form of the HER2 oncoprotein, drives an immunosuppressive program in HER2 breast cancer that limits trastuzumab deruxtecan efficacy.
Dong Hu, Xiaoshuang Lyu, Zheqi Li, Prasanna Ekambaram, Anushka Dongre, Jennifer M Atkinson

Nat Cancer· July 2025

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Correction: Single-Cell Transcriptomic Heterogeneity in Invasive Ductal and Lobular Breast Cancer Cells.
Fangyuan Chen, Kai Ding, Nolan Priedigkeit, Ashuvinee Elangovan, Kevin M Levine, Jennifer M Atkinson

Cancer Res· December 2024

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Systemic and local chronic inflammation and hormone disposition promote a tumor-permissive environment for breast cancer in older women.
Neil Carleton, Sanghoon Lee, Ruxuan Li, Jian Zou, Daniel D Brown, Jennifer M Atkinson

bioRxiv· October 2024

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ESR1 Fusions Invoke Breast Cancer Subtype-Dependent Enrichment of Ligand-Independent Oncogenic Signatures and Phenotypes.
Megan E Yates, Hunter Waltermire, Kanako Mori, Zheqi Li, Yiting Li, Jennifer M Atkinson

Endocrinology· August 2024

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Spatial molecular profiling of mixed invasive ductal and lobular breast cancers reveals heterogeneity in intrinsic molecular subtypes, oncogenic signatures, and mutations.
Osama Shiraz Shah, Azadeh Nasrazadani, Julia Foldi, Jennifer M Atkinson, Celina G Kleer

Proc Natl Acad Sci U S A· July 2024

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Spatial molecular profiling of mixed invasive ductal-lobular breast cancers reveals heterogeneity in intrinsic molecular subtypes, oncogenic signatures, and mutations.
Osama Shiraz Shah, Azadeh Nasrazadani, Julia Foldi, Jennifer M Atkinson, Celina G Kleer

bioRxiv· June 2024

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Estrogen regulation and functional role of FGFR4 in estrogen receptor positive breast cancer.
Kai Ding, Lyuqin Chen, Kevin Levine, Matthew Sikora, Nilgun Tasdemir, Jennifer M Atkinson

bioRxiv· March 2024

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Systems approach for congruence and selection of cancer models towards precision medicine.
Jian Zou, Osama Shah, Yu-Chiao Chiu, Tianzhou Ma, Jennifer M Atkinson

PLoS Comput Biol· January 2024

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WCRC-25: A novel luminal Invasive Lobular Carcinoma cell line model.
Ashuvinee Elangovan, Emily A Bossart, Ahmed Basudan, Nilgun Tasdemir, Osama Shiraz Shah, Jennifer M Atkinson

bioRxiv· September 2023

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fusion proteins invoke breast cancer subtype-dependent enrichment of ligand independent pro-oncogenic signatures and phenotypes.
Megan E Yates, Zheqi Li, Yiting Li, Hannah Guzolik, Xiaosong Wang, Jennifer M Atkinson

bioRxiv· September 2023

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FOXA1 Reprogramming Dictates Retinoid X Receptor Response in ESR1-Mutant Breast Cancer.
Yang Wu, Zheqi Li, Abdalla M Wedn, Allison N Casey, Daniel Brown, Jennifer M Atkinson

Mol Cancer Res· June 2023

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Mixed invasive ductal lobular carcinoma is clinically and pathologically more similar to invasive lobular than ductal carcinoma.
Azadeh Nasrazadani, Yujia Li, Yusi Fang, Osama Shah, Jennifer M Atkinson

Br J Cancer· April 2023

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RET signaling in breast cancer therapeutic resistance and metastasis.
Geoffrey Pecar, Simeng Liu, Jagmohan Hooda, Jennifer M Atkinson, Steffi Oesterreich

Breast Cancer Res· March 2023

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Loss of E-cadherin Induces IGF1R Activation and Reveals a Targetable Pathway in Invasive Lobular Breast Carcinoma.
Ashuvinee Elangovan, Jagmohan Hooda, Laura Savariau, Susrutha Puthanmadhomnarayanan, Megan E Yates, Jennifer M Atkinson

Mol Cancer Res· September 2022

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Getting to YES: The Evolution of the University of Pittsburgh Medical Center Hillman Cancer Center Youth Enjoy Science (YES) Academy.
Joseph C Ayoob, Richard D Boyce, Solomon Livshits, Tullia C Bruno, Greg M Delgoffe, Jennifer M Atkinson

J STEM Outreach· August 2022

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Hotspot ESR1 Mutations Are Multimodal and Contextual Modulators of Breast Cancer Metastasis.
Zheqi Li, Yang Wu, Megan E Yates, Nilgun Tasdemir, Amir Bahreini, Jennifer M Atkinson

Cancer Res· April 2022

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ESR1 mutant breast cancers show elevated basal cytokeratins and immune activation.
Zheqi Li, Olivia McGinn, Yang Wu, Amir Bahreini, Nolan M Priedigkeit, Jennifer M Atkinson

Nat Commun· April 2022

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Mapping molecular subtype specific alterations in breast cancer brain metastases identifies clinically relevant vulnerabilities.
Nicola Cosgrove, Damir Varešlija, Stephen Keelan, Ashuvinee Elangovan, Jennifer M Atkinson

Nat Commun· January 2022

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The Development and Implementation of an Autopsy/ Tissue Donation for Breast Cancer Research.
Margaret Rosenzweig, Lori A Miller, Adrian V Lee, Steffi Oesterreich, Humberto E Trejo Bittar, Jennifer M Atkinson

New Bioeth· December 2021

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Prognostic Utility of Breast Cancer Index to Stratify Distant Recurrence Risk in Invasive Lobular Carcinoma.
Raquel Nunes, Tal Sella, Kai Treuner, Jennifer M Atkinson, Jenna Wong

Clin Cancer Res· October 2021

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Exosomes in Breast Cancer - Mechanisms of Action and Clinical Potential.
Tiantong Liu, Jagmohan Hooda, Jennifer M Atkinson, Theresa L Whiteside, Steffi Oesterreich

Mol Cancer Res· June 2021

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Single-Cell Transcriptomic Heterogeneity in Invasive Ductal and Lobular Breast Cancer Cells.
Fangyuan Chen, Kai Ding, Nolan Priedigkeit, Ashuvinee Elangovan, Kevin M Levine, Jennifer M Atkinson

Cancer Res· January 2021

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Differential Regulation and Targeting of Estrogen Receptor α Turnover in Invasive Lobular Breast Carcinoma.
Sreeja Sreekumar, Kevin M Levine, Matthew J Sikora, Jian Chen, Nilgun Tasdemir, Jennifer M Atkinson

Endocrinology· September 2020

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Patient treatment and outcome after breast cancer orbital and periorbital metastases: a comprehensive case series including analysis of lobular versus ductal tumor histology.
Martin Blohmer, Li Zhu, Jennifer M Atkinson, Sushil Beriwal, Joshua L Rodríguez-López

Breast Cancer Res· June 2020

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