Publications by authors named "Jennifer D Stone"

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Engineered CAR T Cells Targeting the Cancer-Associated Tn-Glycoform of the Membrane Mucin MUC1 Control Adenocarcinoma.
Avery D Posey, Robert D Schwab, Alina C Boesteanu, Catharina Steentoft, Ulla Mandel, Boris Engels, Jennifer D Stone, Thomas D Madsen, Karin Schreiber, Kathleen M Haines

Immunity· June 2016

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ABBV-303 is a Natural Killer Cell Engager Specific for c-Met-Expressing Tumors.
Jennifer D Stone, Kamonwan Fish, Devika Ashok, Laura M McKay, Saeed S Akhand

Cancer Res· October 2025

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ABBV-184: A Novel Survivin-specific TCR/CD3 Bispecific T-cell Engager is Active against Both Solid Tumor and Hematologic Malignancies.
Adam S Chervin, Jennifer D Stone, Iwona Konieczna, Kelly M Calabrese, Ningyan Wang

Mol Cancer Ther· August 2023

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T-cell Receptors Engineered for Peptide Specificity Can Mediate Optimal T-cell Activity without Self Cross-Reactivity.
Preeti Sharma, Daniel T Harris, Jennifer D Stone, David M Kranz

Cancer Immunol Res· December 2019

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Breaking tolerance with engineered class I antigen-presenting molecules.
Christopher A Parks, Kalli R Henning, Kevin D Pavelko, Michael J Hansen, Virginia P Van Keulen, Jennifer D Stone

Proc Natl Acad Sci U S A· February 2019

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Comparison of T Cell Activities Mediated by Human TCRs and CARs That Use the Same Recognition Domains.
Daniel T Harris, Marlies V Hager, Sheena N Smith, Qi Cai, Jennifer D Stone

J Immunol· February 2018

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A Multiplex Assay for Detection of Staphylococcal and Streptococcal Exotoxins.
Preeti Sharma, Ningyan Wang, Adam S Chervin, Cheryl L Quinn, Jennifer D Stone

PLoS One· May 2016

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TCR affinity for p/MHC formed by tumor antigens that are self-proteins: impact on efficacy and toxicity.
Jennifer D Stone, Daniel T Harris, David M Kranz

Curr Opin Immunol· April 2015

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A novel T cell receptor single-chain signaling complex mediates antigen-specific T cell activity and tumor control.
Jennifer D Stone, Daniel T Harris, Carolina M Soto, Adam S Chervin, David H Aggen

Cancer Immunol Immunother· November 2014

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Role of T cell receptor affinity in the efficacy and specificity of adoptive T cell therapies.
Jennifer D Stone, David M Kranz

Front Immunol· August 2013

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Design and characterization of a protein superagonist of IL-15 fused with IL-15Rα and a high-affinity T cell receptor.
Jennifer D Stone, Adam S Chervin, Hans Schreiber, David M Kranz

Biotechnol Prog· May 2013

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MHC-class I-restricted CD4 T cells: a nanomolar affinity TCR has improved anti-tumor efficacy in vivo compared to the micromolar wild-type TCR.
Carolina M Soto, Jennifer D Stone, Adam S Chervin, Boris Engels, Hans Schreiber

Cancer Immunol Immunother· February 2013

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A sensitivity scale for targeting T cells with chimeric antigen receptors (CARs) and bispecific T-cell Engagers (BiTEs).
Jennifer D Stone, David H Aggen, Andrea Schietinger, Hans Schreiber, David M Kranz

Oncoimmunology· September 2012

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T cell receptor engineering.
Jennifer D Stone, Adam S Chervin, David H Aggen, David M Kranz

Methods Enzymol· April 2012

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Interaction of streptavidin-based peptide-MHC oligomers (tetramers) with cell-surface TCRs.
Jennifer D Stone, Maxim N Artyomov, Adam S Chervin, Arup K Chakraborty, Herman N Eisen

J Immunol· December 2011

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Opposite effects of endogenous peptide-MHC class I on T cell activity in the presence and absence of CD8.
Jennifer D Stone, David H Aggen, Adam S Chervin, Samanthi Narayanan, Thomas M Schmitt

J Immunol· May 2011

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T cells use rafts for survival.
Jennifer D Stone, David M Kranz

Immunity· February 2010

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Cutting edge: inhibitory effects of CD4 and CD8 on T cell activation induced by high-affinity noncognate ligands.
Adam S Chervin, Jennifer D Stone, Natalie A Bowerman, David M Kranz

J Immunol· December 2009

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The impact of TCR-binding properties and antigen presentation format on T cell responsiveness.
Adam S Chervin, Jennifer D Stone, Phillip D Holler, Ailin Bai, Jianzhu Chen

J Immunol· July 2009

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Biosensor detection systems: engineering stable, high-affinity bioreceptors by yeast surface display.
Sarah A Richman, David M Kranz, Jennifer D Stone

Methods Mol Biol· March 2009

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T-cell receptor binding affinities and kinetics: impact on T-cell activity and specificity.
Jennifer D Stone, Adam S Chervin, David M Kranz

Immunology· February 2009

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Distinct CDR3 conformations in TCRs determine the level of cross-reactivity for diverse antigens, but not the docking orientation.
Lindsay L Jones, Leremy A Colf, Jennifer D Stone, K Christopher Garcia, David M Kranz

J Immunol· November 2008

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Different thermodynamic binding mechanisms and peptide fine specificities associated with a panel of structurally similar high-affinity T cell receptors.
Lindsay L Jones, Leremy A Colf, Alexander J Bankovich, Jennifer D Stone, Yi-Gui Gao

Biochemistry· November 2008

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Noble metals strip peptides from class II MHC proteins.
Stephen L De Wall, Corrie Painter, Jennifer D Stone, Rajintha Bandaranayake, Don C Wiley

Nat Chem Biol· April 2006

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CD8 T cells, like CD4 T cells, are triggered by multivalent engagement of TCRs by MHC-peptide ligands but not by monovalent engagement.
Jennifer D Stone, Lawrence J Stern

J Immunol· February 2006

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