Publications by authors named "Jessica Fortin"

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Epigallocatechin-3-Gallate: A potential amyloid Fibril Disaggregator of Serum amyloid A1.
Natalie G Horgan, Anabela Djurovic-Topalovic, Taiwo A Ademoye, Hannah I Reyes-Charles, Natsumi Kobayashi, Jessica S Fortin

Biochem Biophys Rep· December 2025

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A high-throughput drug screening assay for anti-tau aggregation using split GFP and flow cytometry.
Omnia M H Ibrahium, Taiwo A Ademoye, Jessica S Fortin, Raluca Ostafe

Sci Rep· October 2025

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Utilizing image analysis by optical density to evaluate changes in hematoxylin and eosin staining quality after reagent overuse.
Hannah M Benton, Mark Butters, Miles Brous, Brad Bolon, Karen Copeland, Jessica S Fortin

J Histotechnol· September 2025

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In Vitro Evaluation of Amide-Linked Coumarin Scaffolds for the Inhibition of α‑Synuclein and Tau Aggregation.
Taiwo A Ademoye, Susantha K Ganegamage, Behrad Masoudi, Omnia M H Ibrahium, Heba Alnakhala, Jessica S Fortin

ACS Omega· September 2025

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The aggregation tendencies of the signal peptide regions of prone and not prone to aggregate proteins.
Natalie G Horgan, Anabela Djurovic-Topalovic, Taiwo A Ademoye, Jessica S Fortin

Biochem Biophys Rep· June 2025

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Updates on Tau-Related Drug Targets and Potential Disease-Modifying Therapies for Alzheimer's Disease.
Anabela Djurovic-Topalovic, Natalie G Horgan, Jessica S Fortin

Am J Pathol· June 2025

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Classification of amyloidosis and protein misfolding disorders in animals 2024: A review on pathology and diagnosis.
Susumu Iwaide, Tomoaki Murakami, Niki Sedghi Masoud, Natsumi Kobayashi, Jessica S Fortin

Vet Pathol· March 2025

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Inspecting the Triazole Scaffold as Powerful Antifibril Agents against 2N4R Tau and α-Synuclein Aggregates.
Ahmed A Elbatrawy, Taiwo A Ademoye, Heba Alnakhala, Arati Tripathi, Xiongwei Zhu, Jessica S Fortin

ACS Omega· February 2025

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Exploring the rhodanine universe: Design and synthesis of fluorescent rhodanine-based derivatives as anti-fibrillar and anti-oligomer agents against α-synuclein and 2N4R tau.
Ahmed A Elbatrawy, Taiwo A Ademoye, Heba Alnakhala, Arati Tripathi, Germán Plascencia-Villa, Jessica S Fortin

Bioorg Med Chem· December 2024

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Evaluation of Alpha-Synuclein and Tau Antiaggregation Activity of Urea and Thiourea-Based Small Molecules for Neurodegenerative Disease Therapeutics.
Susantha K Ganegamage, Taiwo A Ademoye, Henika Patel, Heba Alnakhala, Arati Tripathi, Jessica S Fortin

ACS Chem Neurosci· November 2024

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Understanding alpha-synuclein aggregation propensity in animals and humans.
Natalie G Horgan, Annie M McCarty, Ashley A Hetak, Hailey B Penticoff, Jessica S Fortin

Biochem Biophys Rep· September 2024

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Corrigendum to "Revisiting misfolding propensity of serum amyloid A1: Special focus on the signal peptide region" [Biochem. Biophys. Rep. 31 (2022) 1-9/101284].
Morgan S Haines, Eduardo Ramirez, Kendall B E Moore, Jessica S Fortin

Biochem Biophys Rep· September 2024

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Lumbar vertebral bone density is decreased in horses with pituitary pars intermedia dysfunction.
Aimee C Colbath, Jessica S Fortin, Caroline M Burglass, Char Panek, Fernando B Vergara-Hernandez

Equine Vet J· March 2024

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Discovery of small molecule benzothiazole and indole derivatives tackling tau 2N4R and α-synuclein fibrils.
Ahmed A Elbatrawy, Taiwo A Ademoye, Heba Alnakhala, Arati Tripathi, Ashique Zami, Jessica S Fortin

Bioorg Med Chem· February 2024

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1,4-Diurea- and 1,4-Dithiourea-Substituted Aromatic Derivatives Selectively Inhibit α-Synuclein Oligomer Formation .
Susantha K Ganegamage, Eduardo Ramirez, Heba Alnakhala, Arati Tripathi, Cuong Calvin Duc Nguyen, Jessica S Fortin

ACS Omega· January 2024

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Diabetes mellitus drug discovery: insights into targeting feline and human amylin with small molecules.
Kendall B E Moore, Natalie G Horgan, Brooke Lenters, Jessica S Fortin

Vet Q· December 2023

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Investigation of serum amyloid a within animal species focusing on the 1-25 amino acid region.
Natalie G Horgan, Kendall B E Moore, Jessica S Fortin

Vet Q· December 2023

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Evaluation of N- and O-Linked Indole Triazines for a Dual Effect on α-Synuclein and Tau Aggregation.
Eduardo Ramirez, Susantha K Ganegamage, Sehong Min, Henika Patel, Adedayo Ogunware, Jessica S Fortin

ACS Chem Neurosci· November 2023

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5-Nitro-1,2-benzothiazol-3-amine and -Ethyl-1-[(ethylcarbamoyl)(5-nitro-1,2-benzothiazol-3-yl)amino]formamide Modulate α-Synuclein and Tau Aggregation.
Eduardo Ramirez, Susantha K Ganegamage, Ahmed A Elbatrawy, Heba Alnakhala, Kazuma Shimanaka, Jessica S Fortin

ACS Omega· June 2023

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Hyperphosphorylated tau (p-tau) and drug discovery in the context of Alzheimer's disease and related tauopathies.
Kendall B E Moore, Ta-Jung Hung, Jessica S Fortin

Drug Discov Today· March 2023

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Discovery of 4-aminoindole carboxamide derivatives to curtail alpha-synuclein and tau isoform 2N4R oligomer formation.
Eduardo Ramirez, Sehong Min, Susantha K Ganegamage, Kazuma Shimanaka, Magaly Guzman Sosa, Jessica S Fortin

Results Chem· January 2023

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Anti-fibrillization effects of sulfonamide derivatives on -synuclein and hyperphosphorylated tau isoform 1N4R.
Jessica S Fortin, Kazuma Shimanaka, A Prasanth Saraswati, Mengyu Liu, Kuang-Wei Wang

J Mol Struct· November 2022

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Recent Advances in the Discovery of Therapeutics to Curtail Islet Amyloid Polypeptide Aggregation for Type 2 Diabetes Treatment.
Alyssa A Smith, Kendall B E Moore, Patrick M Ambs, Akella Prasanth Saraswati, Jessica S Fortin

Adv Biol (Weinh)· October 2022

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Revisiting misfolding propensity of serum amyloid A1: Special focus on the signal peptide region.
Morgan S Haines, Eduardo Ramirez, Kendall B E Moore, Jessica S Fortin

Biochem Biophys Rep· September 2022

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Equine pituitary pars intermedia dysfunction: a spontaneous model of synucleinopathy.
Jessica S Fortin, Ashley A Hetak, Kelsey E Duggan, Caroline M Burglass, Hailey B Penticoff

Sci Rep· August 2021

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