Publications by authors named "Jiajun Dong"

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A small molecule inhibitor of PTP1B and PTPN2 enhances T cell anti-tumor immunity.
Shuwei Liang, Eric Tran, Xin Du, Jiajun Dong, Harrison Sudholz, Hao Chen, Zihan Qu, Nicholas D Huntington, Jeffrey J Babon, Nadia J Kershaw

Nat Commun· July 2023

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Macrocyclic Peptides Containing an Imidazopyridinium (IP) Unit Display Enhanced Passive Cell Permeability.
Bo Li, Joshua Parker, Skyler Briggs, Jiajun Dong, James M Burke

bioRxiv· October 2025

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Understanding the stability landscape of LbCas12a by deep analysis of stabilizing mutations and mutation combinations.
Jiajun Dong, Shaojie Wang, Wenxue Xu, Jingyao Xin, Jia Liu

Protein Sci· September 2025

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1T/2H-MoS Nanoclusters as Plasmon-Free Surface-Enhanced Raman Spectroscopy Substrates for Ultrasensitive Detection of Environmental Pollutants.
Zhenyu Wen, Wenjie Zhu, Yongxue Chen, Huanhuan Sun, Lin Zhu, Jiajun Dong

Langmuir· September 2025

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Deep Learning-Enhanced Spectroscopic Technologies for Food Quality Assessment: Convergence and Emerging Frontiers.
Zhichen Lun, Xiaohong Wu, Jiajun Dong, Bin Wu

Foods· July 2025

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Discovery and Evaluation of Active Site-Directed, Potent, and Selective Sulfophenyl Acetic Amide-Based Inhibitors for the Laforin Phosphatase.
Jianping Lin, Rongjun He, Zihan Qu, Jiajun Dong, Aaron D Krabill

J Med Chem· May 2025

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General approach for synthesizing hexagonal diamond by heating post-graphite phases.
Desi Chen, Guwen Chen, Long Lv, Jiajun Dong, Yuchen Shang

Nat Mater· April 2025

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Room-temperature phosphorescence and anomalous piezochromism in molecular crystals enabled by iodine atomic orbital sharing.
Tongge Xu, Chunguang Zhai, Ziyao Liu, Xiaoying Yang, Shuhe Hu, Jiajun Dong

Nat Commun· April 2025

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Discovery and evaluation of novel SHIP-1 inhibitors.
Jinmin Miao, Jianping Lin, Jiajun Dong, Ovini Amarasinghe, Emily R Mason

Bioorg Med Chem· November 2024

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A general temperature-guided language model to design proteins of enhanced stability and activity.
Fan Jiang, Mingchen Li, Jiajun Dong, Yuanxi Yu, Xinyu Sun

Sci Adv· November 2024

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Endohedral metallofullerenes as nanoreactors: Regulating the ring-opening reaction of m-xylene at a molecular level under pressure.
Ying Zhang, Shuang Liu, Si Yin, Xiu Yin, Lei Yue, Jiajun Dong

J Chem Phys· September 2024

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Development of Novel Phosphonodifluoromethyl-Containing Phosphotyrosine Mimetics and a First-In-Class, Potent, Selective, and Bioavailable Inhibitor of Human CDC14 Phosphatases.
Jiajun Dong, Brenson A Jassim, Kedric L Milholland, Zihan Qu, Yunpeng Bai

J Med Chem· June 2024

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Off-target autophagy inhibition by SHP2 allosteric inhibitors contributes to their antitumor activity in RAS-driven cancers.
Yiming Miao, Yunpeng Bai, Jinmin Miao, Allison A Murray, Jianping Lin, Jiajun Dong

J Clin Invest· June 2024

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Single-cell RNA sequencing uncovers the cell type-dependent transcriptomic changes in the retrosplenial cortex after peripheral nerve injury.
Jing-Hua Wang, Cheng Wu, Yan-Na Lian, Xiao-Wen Cao, Zi-Yue Wang, Jia-Jun Dong

Cell Rep· December 2023

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Protein tyrosine phosphatases as emerging targets for cancer immunotherapy.
Zihan Qu, Jiajun Dong, Zhong-Yin Zhang

Br J Pharmacol· December 2023

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[Effect of transurethral thuliumlaser vapoenucleation of the prostate with low-power conventional pulse mode on sexual function in patients with benign prostatic hyperplasia].
Yi-Feng Xue, Jia-Jun Dong, Yun-Hua Xu, Ping Wang, Lei Pan

Zhonghua Nan Ke Xue· December 2023

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Realizing long range π-conjugation in phenanthrene and phenanthrene-based molecular crystals for anomalous piezoluminescence.
Tongge Xu, Xiu Yin, Chunguang Zhai, Desi Chen, Xiaoying Yang, Jiajun Dong

Chem Sci· November 2023

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Discovery of a selective TC-PTP degrader for cancer immunotherapy.
Jinmin Miao, Jiajun Dong, Yiming Miao, Yunpeng Bai, Zihan Qu

Chem Sci· November 2023

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SHIP1 therapeutic target enablement: Identification and evaluation of inhibitors for the treatment of late-onset Alzheimer's disease.
Cynthia D Jesudason, Emily R Mason, Shaoyou Chu, Adrian L Oblak, June Javens-Wolfe, Jiajun Dong

Alzheimers Dement (N Y)· November 2023

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Enhancement of short/medium-range order and thermal conductivity in ultrahard sp amorphous carbon by C precursor.
Yuchen Shang, Mingguang Yao, Zhaodong Liu, Rong Fu, Longbiao Yan, Jiajun Dong

Nat Commun· November 2023

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Discovery of a SHP2 Degrader with In Vivo Anti-Tumor Activity.
Jinmin Miao, Yunpeng Bai, Yiming Miao, Zihan Qu, Jiajun Dong

Molecules· October 2023

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Application effect of head-mounted mixed reality device combined with 3D printing model in neurosurgery ventricular and hematoma puncture training.
Yilong Peng, Zhengyuan Xie, Shaoai Chen, Yi Wu, Jiajun Dong

BMC Med Educ· September 2023

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COVID-19 hospitalization increases the risk of developing glioblastoma: a bidirectional Mendelian-randomization study.
Jiajun Dong, Shengnan Wang, Haoqun Xie, Yanhao Mou, Hao Zhu

Front Oncol· August 2023

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Novel potential urinary biomarkers for effective diagnosis and prognostic evaluation of high-grade bladder cancer.
Zhi-Guo Zhang, Zhen-Duo Shi, Jia-Jun Dong, Yu-Ang Chen, Ming-Yang Cao, Yang Dong

Transl Cancer Res· August 2023

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A small molecule inhibitor of PTP1B and PTPN2 enhances T cell anti-tumor immunity.
Shuwei Liang, Eric Tran, Xin Du, Jiajun Dong, Harrison Sudholz

bioRxiv· June 2023

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