Publications by authors named "Jianglei Chen"

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The Single Administration of a Chromophore Alleviates Neural Defects in Diabetic Retinopathy.
Volha V Malechka, Jianglei Chen, Rui Cheng, Jian-Xing Ma, Gennadiy Moiseyev

Am J Pathol· July 2020

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Hepatocyte and adipocyte CDO1-mediated intracellular cysteine catabolism differentially modulates diet-induced obesity and fatty liver in mice.
Jianglei Chen, Yung-Dai Clayton, Yanhong Du, David Matye, Lijie Gu

bioRxiv· December 2025

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Gly-β-MCA is a potent anti-cholestasis agent against "human-like" hydrophobic bile acid-induced biliary injury in mice.
Mohammad Nazmul Hasan, Huaiwen Wang, Wenyi Luo, Yung Dai Clayton, Lijie Gu, Jianglei Chen

J Lipid Res· October 2024

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Deletion of hepatocyte cysteine dioxygenase type 1, a bile acid repressed gene, enhances glutathione synthesis and ameliorates acetaminophen hepatotoxicity.
Jianglei Chen, David Matye, Yung Dai Clayton, Yanhong Du, Mohammad Nazmul Hasan

Biochem Pharmacol· April 2024

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Cullin 3 RING E3 ligase inactivation causes NRF2-dependent NADH reductive stress, hepatic lipodystrophy, and systemic insulin resistance.
Lijie Gu, Yanhong Du, Jianglei Chen, Mohammad Nazmul Hasan, Yung Dai Clayton

Proc Natl Acad Sci U S A· April 2024

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Hierarchical porous Fe-N/C@surfactant composites synthesized by a surfactant-assisted strategy as high-performance bifunctional oxygen electrodes for rechargeable zinc-air batteries.
Wen-Jun Niu, Ru-Ji Li, Wei-Wei Zhao, Ying-Yun Yan, Er-Peng Feng, Jiang-Lei Chen

J Colloid Interface Sci· November 2023

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Glycine-β-Muricholic Acid Improves Liver Fibrosis and Gut Barrier Function by Reducing Bile Acid Pool Size and Hydrophobicity in Male Knockout Mice.
Mohammad Nazmul Hasan, Jianglei Chen, Huaiwen Wang, Yanhong Du, Yung Dai Clayton

Cells· May 2023

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Combining ASBT inhibitor and FGF15 treatments enhances therapeutic efficacy against cholangiopathy in female but not male Cyp2c70 KO mice.
Mohammad Nazmul Hasan, Jianglei Chen, David Matye, Huaiwen Wang, Wenyi Luo

J Lipid Res· March 2023

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Inhibition of miR-101-3p prevents human aortic valve interstitial cell calcification through regulation of CDH11/SOX9 expression.
Jianglei Chen, Yi Lin, Zhongjie Sun

Mol Med· February 2023

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TFEB regulates sulfur amino acid and coenzyme A metabolism to support hepatic metabolic adaptation and redox homeostasis.
David Matye, Sumedha Gunewardena, Jianglei Chen, Huaiwen Wang, Yifeng Wang, Cheng Chen

Nat Commun· September 2022

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Soluble very low-density lipoprotein receptor (sVLDLR) inhibits fibrosis in neovascular age-related macular degeneration.
Xiang Ma, Yusuke Takahashi, Wenjing Wu, Jianglei Chen, Marcus Dehdarani

FASEB J· December 2021

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ADAM17 mediates ectodomain shedding of the soluble VLDL receptor fragment in the retinal epithelium.
Xiang Ma, Yusuke Takahashi, Wenjing Wu, Wentao Liang, Jianglei Chen

J Biol Chem· October 2021

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Interphotoreceptor Retinol-Binding Protein Ameliorates Diabetes-Induced Retinal Dysfunction and Neurodegeneration Through Rhodopsin.
Jianglei Chen, Yan Shao, Temmy Sasore, Gennadiy Moiseyev, Kelu Zhou

Diabetes· March 2021

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Detection and Quantification of Retinal Neovascularization Using BrdU Incorporation.
Yan Shao, Jianglei Chen, Xiao-Rong Li, Jian-Xing Ma

Transl Vis Sci Technol· August 2020

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Pathogenic role of human C-reactive protein in diabetic retinopathy.
Fangfang Qiu, Xiang Ma, Young-Hwa Shin, Jianglei Chen, Qian Chen

Clin Sci (Lond)· July 2020

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A Protective Effect of PPARα in Endothelial Progenitor Cells Through Regulating Metabolism.
Yan Shao, Jianglei Chen, Li-Jie Dong, Xuemin He, Rui Cheng

Diabetes· November 2019

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Canonical Wnt Signaling Promotes Neovascularization Through Determination of Endothelial Progenitor Cell Fate via Metabolic Profile Regulation.
Yan Shao, Jianglei Chen, Willard Freeman, Li-Jie Dong, Zhi-Hui Zhang

Stem Cells· October 2019

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miRNA-451a regulates RPE function through promoting mitochondrial function in proliferative diabetic retinopathy.
Yan Shao, Li-Jie Dong, Yusuke Takahashi, Jianglei Chen, Xun Liu, Qian Chen

Am J Physiol Endocrinol Metab· March 2019

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Secreted Klotho Attenuates Inflammation-Associated Aortic Valve Fibrosis in Senescence-Accelerated Mice P1.
Jianglei Chen, Jun Fan, Shirley Wang, Zhongjie Sun

Hypertension· May 2018

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Deficiency in the anti-aging gene Klotho promotes aortic valve fibrosis through AMPKα-mediated activation of RUNX2.
Jianglei Chen, Yi Lin, Zhongjie Sun

Aging Cell· October 2016

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Antiaging Gene Klotho Deficiency Promoted High-Fat Diet-Induced Arterial Stiffening via Inactivation of AMP-Activated Protein Kinase.
Yi Lin, Jianglei Chen, Zhongjie Sun

Hypertension· March 2016

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A novel bacterial expression method with optimized parameters for very high yield production of triple-labeled proteins.
Victoria Murray, Yuefei Huang, Jianglei Chen, Jianjun Wang, Qianqian Li

Methods Mol Biol· April 2012

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Topology of human apolipoprotein E3 uniquely regulates its diverse biological functions.
Jianglei Chen, Qianqian Li, Jianjun Wang

Proc Natl Acad Sci U S A· September 2011

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A segmental labeling strategy for unambiguous determination of domain-domain interactions of large multi-domain proteins.
Jianglei Chen, Jianjun Wang

J Biomol NMR· August 2011

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Two structural and functional domains of MESD required for proper folding and trafficking of LRP5/6.
Jianglei Chen, Chia-Chen Liu, Qianqian Li, Christian Nowak, Guojun Bu

Structure· March 2011

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