Publications by authors named "John D Catravas"

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Quercetin and Vitamin C: An Experimental, Synergistic Therapy for the Prevention and Treatment of SARS-CoV-2 Related Disease (COVID-19).
Ruben Manuel Luciano Colunga Biancatelli, Max Berrill, John D Catravas, Paul E Marik

August 2020

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The PTP4A3 inhibitor KVX-053 reduces Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) virulence, inflammation, and development of acute lung injury in K18-hACE2 mice.
Ruben M L Colunga-Biancatelli, Pavel A Solopov, Caitlin M Woodson, Irving Coy Allen, Ivan Akhrymuk, John D Catravas

Respir Res· October 2025

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Combination of HSP90 Inhibitors and HSP70 Inducers Prevent Hydrochloric Acid-Induced Pulmonary Fibrosis in Rabbits.
Ruben M L Colunga Biancatelli, Pavel A Solopov, Tierney Day, Dan E Austin, Len E Murray, John D Catravas

Int J Mol Sci· January 2025

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KVX-053, a protein tyrosine phosphatase 4A3 inhibitor, ameliorates SARS-CoV-2 spike protein subunit 1-induced acute lung injury in mice.
Pavel A Solopov, Ruben Manuel Luciano Colunga Biancatelli, Tierney Day, Betsy Gregory, Elizabeth R Sharlow, John D Catravas

J Pharmacol Exp Ther· November 2024

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A novel Non-rodent animal model of hydrochloric acid-induced acute and chronic lung injury.
Pavel A Solopov, Ruben Manuel Luciano Colunga Biancatelli, Tierney Day, Christiana Dimitropoulou, John D Catravas

Respir Res· October 2024

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A Novel Non-Rodent Animal Model of Hydrochloric Acid-Induced acute and chronic lung injury.
Pavel A Solopov, Ruben Manuel Luciano Colunga Biancatelli, Tierney Day, Christiana Dimitropoulou, John D Catravas

Res Sq· August 2024

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HSP70 Is a Critical Regulator of HSP90 Inhibitor's Effectiveness in Preventing HCl-Induced Chronic Lung Injury and Pulmonary Fibrosis.
Ruben M L Colunga Biancatelli, Pavel A Solopov, Tierney Day, Betsy Gregory, Michael Osei-Nkansah, John D Catravas

Int J Mol Sci· February 2024

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Synergistic effects of nanosecond pulsed plasma and electric field on inactivation of pancreatic cancer cells in vitro.
Edwin A Oshin, Zobia Minhas, Ruben M L Colunga Biancatelli, John D Catravas, Richard Heller

Sci Rep· January 2024

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An acute respiratory distress syndrome drug development collaboration stimulated by the Virginia Drug Discovery Consortium.
John S Lazo, Ruben M L Colunga-Biancatelli, Pavel A Solopov, John D Catravas

SLAS Discov· September 2023

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Synergistic effects of nanosecond pulsed plasma and electric field on inactivation of pancreatic cancer cells in vitro.
Edwin A Oshin, Zobia Minhas, Ruben M L Colunga Biancatelli, John D Catravas, Richard Heller

Res Sq· July 2023

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Activation of cannabinoid-2 receptor protects against Pseudomonas aeruginosa induced acute lung injury and inflammation.
Nagaraja Nagre, Gregory Nicholson, Xiaofei Cong, Janette Lockett, Andrew C Pearson, John D Catravas

Respir Res· December 2022

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Optimizing antidotal treatment with the oral HSP90 inhibitor TAS-116 against hydrochloric acid-induced pulmonary fibrosis in mice.
Pavel A Solopov, Ruben Manuel Luciano Colunga Biancatelli, Christiana Dimitropolou, Tierney Day, John D Catravas

Front Pharmacol· November 2022

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The Paradox of Pulmonary Vascular Resistance: Restoration of Pulmonary Capillary Recruitment as a for True Therapeutic Success in Pulmonary Arterial Hypertension.
David Langleben, Stylianos E Orfanos, Benjamin D Fox, Nathan Messas, Michele Giovinazzo, John D Catravas

J Clin Med· August 2022

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Alcohol Increases Lung Angiotensin-Converting Enzyme 2 Expression and Exacerbates Severe Acute Respiratory Syndrome Coronavirus 2 Spike Protein Subunit 1-Induced Acute Lung Injury in K18-hACE2 Transgenic Mice.
Pavel A Solopov, Ruben M L Colunga Biancatelli, John D Catravas

Am J Pathol· July 2022

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Endothelial cell-derived extracellular vesicles impair the angiogenic response of coronary artery endothelial cells.
Nigeste Carter, Allison H Mathiesen, Noel Miller, Michael Brown, Ruben M L Colunga Biancatelli, John D Catravas

Front Cardiovasc Med· July 2022

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The Inflammasome NLR Family Pyrin Domain-Containing Protein 3 (NLRP3) as a Novel Therapeutic Target for Idiopathic Pulmonary Fibrosis.
Ruben M L Colunga Biancatelli, Pavel A Solopov, John D Catravas

Am J Pathol· June 2022

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Pulmonary capillary recruitment and distention in mammalian lungs: species similarities.
David Langleben, Benjamin D Fox, Stylianos E Orfanos, Michele Giovinazzo, John D Catravas

Eur Respir Rev· March 2022

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The Heat Shock Protein 90 Inhibitor, AT13387, Protects the Alveolo-Capillary Barrier and Prevents HCl-Induced Chronic Lung Injury and Pulmonary Fibrosis.
Ruben M L Colunga Biancatelli, Pavel Solopov, Christiana Dimitropoulou, Betsy Gregory, Tierney Day, John D Catravas

Cells· March 2022

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HSP90 Inhibitors Modulate SARS-CoV-2 Spike Protein Subunit 1-Induced Human Pulmonary Microvascular Endothelial Activation and Barrier Dysfunction.
Ruben Manuel Luciano Colunga Biancatelli, Pavel A Solopov, Betsy Gregory, Yara Khodour, John D Catravas

Front Physiol· March 2022

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Dietary Phytoestrogens Ameliorate Hydrochloric Acid-Induced Chronic Lung Injury and Pulmonary Fibrosis in Mice.
Pavel Solopov, Ruben Manuel Luciano Colunga Biancatelli, Christiana Dimitropoulou, John D Catravas

Nutrients· October 2021

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The SARS-CoV-2 spike protein subunit S1 induces COVID-19-like acute lung injury in Κ18-hACE2 transgenic mice and barrier dysfunction in human endothelial cells.
Ruben M L Colunga Biancatelli, Pavel A Solopov, Elizabeth R Sharlow, John S Lazo, Paul E Marik, John D Catravas

Am J Physiol Lung Cell Mol Physiol· August 2021

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Age-Dependent Chronic Lung Injury and Pulmonary Fibrosis following Single Exposure to Hydrochloric Acid.
Ruben M L Colunga Biancatelli, Pavel Solopov, Christiana Dimitropoulou, John D Catravas

Int J Mol Sci· August 2021

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The HSP90 Inhibitor, AUY-922, Protects and Repairs Human Lung Microvascular Endothelial Cells from Hydrochloric Acid-Induced Endothelial Barrier Dysfunction.
Ruben M L Colunga Biancatelli, Pavel Solopov, Betsy Gregory, John D Catravas

Cells· June 2021

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Sex-Related Differences in Murine Models of Chemically Induced Pulmonary Fibrosis.
Pavel Solopov, Ruben Manuel Luciano Colunga Biancatelli, Christiana Dimitropoulou, John D Catravas

Int J Mol Sci· May 2021

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Protective Mechanism of the Selective Vasopressin V Receptor Agonist Selepressin against Endothelial Barrier Dysfunction.
Nektarios Barabutis, Margarita Marinova, Pavel Solopov, Mohammad A Uddin, Glenn E Croston, John D Catravas

J Pharmacol Exp Ther· November 2020

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HSP90 Inhibition and Modulation of the Proteome: Therapeutical Implications for Idiopathic Pulmonary Fibrosis (IPF).
Ruben Manuel Luciano Colunga Biancatelli, Pavel Solopov, Betsy Gregory, John D Catravas

Int J Mol Sci· July 2020

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