Publications by authors named "John Gordon"

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Use of human predictive patch test (HPPT) data for the classification of skin sensitization hazard and potency.
Matthias Herzler, Jaleh Abedini, David G Allen, Dori Germolec, John Gordon, Hon-Sum Ko, Joanna Matheson, Emily Reinke, Judy Strickland, Hermann-Josef Thierse

May 2024

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CXCR1 and CXCR2 Antagonism with G31P Attenuates Chemotherapy-Induced Lung Inflammation and Augments the Gefitinib Therapeutic Response in Lung Cancer.
Muhammad Noman Khan, Kang Tian, John R Gordon, Fang Li, Song-Ze Ding

Oncol Res· December 2025

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RTx-303, an Orally Bioavailable Polθ Polymerase Inhibitor That Potentiates PARP Inhibitors in BRCA Mutant Tumors.
Gurushankar Chandramouly, William Fried, John Gordon, Douglas Ralph, Channita Keuk

J Med Chem· November 2025

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Identification of novel molecular drivers, prognostic and diagnostic biomarkers for Inflammatory Bowel Disease (IBD): protocol for the Nottingham/AstraZeneca prospective IBD observational cohort study.
Ana Lilia Serna-Valverde, Eva Rodriguez-Suarez, Daniel J B Marks, Ulf Gehrmann, Jessica Neisen, John Nicholas Gordon, Gordon W Moran

BMJ Open· November 2025

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Historical account of dinitrogen-bridged diiron complex synthesis using a commercial tripodal ligand.
Nathan C Smythe, Joydeb Mondal, Juan G Duque, Russell K Feller, Marco Flores, John C Gordon

Chem Commun (Camb)· July 2025

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Are we hallucinating or can psychedelic drugs modulate the immune system to control inflammation?
Omar Qureshi, Jamie Cowley, Ashley Pegg, Alison J Cooper, John Gordon

Br J Pharmacol· July 2025

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Inhibiting acute, axonal DLK palmitoylation is neuroprotective and avoids deleterious effects of cell-wide DLK inhibition.
Xiaotian Zhang, Heykyeong Jeong, Jingwen Niu, Sabrina M Holland, Brittany N Rotanz, John Gordon

Nat Commun· April 2025

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The long-term vascular and myocardial outcomes in selected Kawasaki disease patients with regression of giant coronary artery aneurysms.
Samuel C Kung, Koichi Miyata, Gabrielle M Colvert, Andrew M Kahn, Lori B Daniels, John B Gordon

Cardiol Young· February 2025

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First Demonstration of PDE11A4 Target Engagement for Potential Treatment of Age-Related Memory Disorders.
Shams Ul Mahmood, Jeremy Eberhard, Charles S Hoffman, Dennis Colussi, John Gordon

J Med Chem· October 2024

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Novel 5-HT receptor antagonists modulate intestinal immune responses and reduce severity of colitis.
Yun Han Kwon, Benjamin E Blass, Huaqing Wang, Jensine A Grondin, Suhrid Banskota, John C Gordon

Am J Physiol Gastrointest Liver Physiol· July 2024

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Correction to "Structure-Activity Relationship of a Pyrrole Based Series of PfPKG Inhibitors as Anti-Malarials".
John A Gilleran, Kutub Ashraf, Melvin Delvillar, Tyler Eck, Raheel Fondekar, John Gordon

J Med Chem· July 2024

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4'-Ethynyl-2'-Deoxycytidine (EdC) Preferentially Targets Lymphoma and Leukemia Subtypes by Inducing Replicative Stress.
Marissa L Calbert, Gurushankar Chandramouly, Clare M Adams, Magali Saez-Ayala, Tatiana Kent, John Gordon

Mol Cancer Ther· May 2024

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A biomarker-stratified comparison of top-down versus accelerated step-up treatment strategies for patients with newly diagnosed Crohn's disease (PROFILE): a multicentre, open-label randomised controlled trial.
Nurulamin M Noor, James C Lee, Simon Bond, Francis Dowling, Biljana Brezina, John N Gordon, Gordon W Moran

Lancet Gastroenterol Hepatol· May 2024

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Towards a taxonomy of geodiversity.
Jan Hjort, Arie C Seijmonsbergen, Julia Kemppinen, Helena Tukiainen, Tuija Maliniemi, John E Gordon

Philos Trans A Math Phys Eng Sci· April 2024

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The status and future of essential geodiversity variables.
Franziska Schrodt, Grant Vernham, Joseph Bailey, Richard Field, John E Gordon

Philos Trans A Math Phys Eng Sci· April 2024

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Psychosocial outcomes of children born via embryo donation.
Salomeh Salari, Seungho Lee, Joshua Mangels, Rebecca Flyckt, Jody Madeira, John Gordon

Hum Reprod· April 2024

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Discovery of a small-molecule inhibitor that traps Polθ on DNA and synergizes with PARP inhibitors.
William Fried, Mrityunjay Tyagi, Leonid Minakhin, Gurushankar Chandramouly, Taylor Tredinnick, John Gordon

Nat Commun· April 2024

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Novel inhibitors of acute, axonal DLK palmitoylation are neuroprotective and avoid the deleterious side effects of cell-wide DLK inhibition.
Xiaotian Zhang, Heykyeong Jeong, Jingwen Niu, Sabrina M Holland, Brittany N Rotanz, John Gordon

bioRxiv· April 2024

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Impact of a varied set of stimuli on a suite of immunological parameters within peripheral blood mononuclear cells: toward a non-animal approach for assessing immune modulation by materials intended for human use.
Stella Cochrane, Ramya Rajagopal, David Sheffield, Fay Stewart, Lindsay Hathaway, John Gordon

Front Toxicol· April 2024

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Structure-Activity Relationship of a Pyrrole Based Series of PfPKG Inhibitors as Anti-Malarials.
John A Gilleran, Kutub Ashraf, Melvin Delvillar, Tyler Eck, Raheel Fondekar, John Gordon

J Med Chem· March 2024

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Boundary of ecosystem services: A response to.
Murray Gray, Nathan Fox, John E Gordon, José Brilha, Abhik Charkraborty

J Environ Manage· February 2024

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Developing a Sustainable Care Delivery Payment Model for Children With Medical Complexity.
Timothy E Corden, Tera Bartelt, Sarah Johaningsmeir, Mary L Ehlenbach, Ryan J Coller, John Gordon

Hosp Pediatr· January 2024

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MC180295 is a highly potent and selective CDK9 inhibitor with preclinical in vitro and in vivo efficacy in cancer.
Hanghang Zhang, Chen Huang, John Gordon, Sijia Yu, George Morton

Clin Epigenetics· January 2024

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DOACs in Patients With Giant Coronary Artery Aneurysms After Kawasaki Disease.
Kirsten B Dummer, Koichi Miyata, Chisato Shimizu, Adriana H Tremoulet, Jill Gleason, John B Gordon

JAMA Netw Open· November 2023

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