Publications by authors named "John J Connolly"

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Trans-ethnic polygenic risk scores for body mass index: An international hundred K+ cohorts consortium study.
Hui-Qi Qu, John J Connolly, Peter Kraft, Jirong Long, Alexandre Pereira, Christopher Flatley, Constance Turman, Bram Prins, Frank Mentch, Paulo A Lotufo

Clin Transl Med· June 2023

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Impact of Genetic Risk Factors on Coronary Heart Disease Risk Across the Age Spectrum in Three Major Race/Ethnicity Groups in the United States.
Mohammadreza Naderian, Johanna L Smith, Marwan E Hamed, Ozan Dikilitas, Josh B Cortopassi, John J Connolly

medRxiv· November 2025

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Pro‑inflammatory insulin‑resistant lipid phenotype in down syndrome identified by H‑NMR metabolomics in obesity-matched African‑American children and young adults.
Hui-Qi Qu, John J Connolly, Garnet Eister, Frank Mentch, Joseph Glessner

Sci Rep· November 2025

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Natural killer cell subpopulations in the peripheral blood of single ventricle/hypoplastic left heart syndrome patients via single-cell RNA sequencing.
Hui-Qi Qu, Kushagra Goel, Kayleigh Ostberg, Diana J Slater, Fengxiang Wang, John J Connolly

Exp Biol Med (Maywood)· September 2025

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Covering medical care costs for participants in the eMERGE Network: Challenges for equity and implementation.
Laura J Rasmussen-Torvik, Katherine E Bonini, Margaret H Harr, Mohammad Ali Abbass, Hana Bangash, John J Connolly

Genet Med· August 2025

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Single-Cell RNA Sequencing of Peripheral Blood Mononuclear Cells in Patients With Single Ventricle/Hypoplastic Left Heart Syndrome.
Hui-Qi Qu, Kayleigh Ostberg, Diana J Slater, Fengxiang Wang, James Snyder, John J Connolly

J Gene Med· August 2025

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The International Health Cohorts Consortium (IHCC) advances population health research and genomic discovery.
John J Connolly, Scott Sundseth, Grant M Wood, Chisom Nwaneri, Geoffrey Ginsburg

Commun Med (Lond)· August 2025

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Risk of Alzheimer's disease in Down syndrome: Insights gained by multi-omics.
Hui-Qi Qu, Yichuan Liu, John J Connolly, Frank D Mentch, Charlly Kao

Alzheimers Dement· April 2025

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Correspondence on "Weighty matters: Considering the ethics of genetic risk scores for obesity" by C. Houtz.
John J Connolly, Molly Hess, Priyanka Maripuri, Shannon Terek, Jasmine Purcell

Genet Med· March 2025

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Kidney multiome-based genetic scorecard reveals convergent coding and regulatory variants.
Hongbo Liu, Amin Abedini, Eunji Ha, Ziyuan Ma, Xin Sheng, John J Connolly

Science· February 2025

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A Comprehensive Approach to Clinical Decision Support in the Return of Genome Informed Risk Assessments to Primary Care Pediatricians.
Dean Karavite, Shannon Terek, John J Connolly, Margaret Harr, Naveen Muthu

Appl Clin Inform· January 2025

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Managing differential performance of polygenic risk scores across groups: Real-world experience of the eMERGE Network.
Anna C F Lewis, Rex L Chisholm, John J Connolly, Edward D Esplin, Joe Glessner

Am J Hum Genet· June 2024

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High Comorbidity of Pediatric Cancers in Patients with Birth Defects: Insights from Whole Genome Sequencing Analysis of Copy Number Variations.
Hui-Qi Qu, Joseph T Glessner, Jingchun Qu, Yichuan Liu, Deborah Watson, John J Connolly

Transl Res· April 2024

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Selection, optimization and validation of ten chronic disease polygenic risk scores for clinical implementation in diverse US populations.
Niall J Lennon, Leah C Kottyan, Christopher Kachulis, Noura S Abul-Husn, Josh Arias, John J Connolly

Nat Med· February 2024

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Participant-guided development of bilingual genomic educational infographics for Electronic Medical Records and Genomics Phase IV study.
Aimiel Casillan, Michelle E Florido, Jamie Galarza-Cornejo, Suzanne Bakken, John A Lynch, John J Connolly

J Am Med Inform Assoc· January 2024

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Trans-ethnic genomic informed risk assessment for Alzheimer's disease: An International Hundred K+ Cohorts Consortium study.
Patrick M Sleiman, Hui-Qi Qu, John J Connolly, Frank Mentch, Alexandre Pereira

Alzheimers Dement· December 2023

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Prospective, multi-site study of healthcare utilization after actionable monogenic findings from clinical sequencing.
Jodell E Linder, Ran Tao, Wendy K Chung, Krzysztof Kiryluk, Cong Liu, John J Connolly

Am J Hum Genet· November 2023

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Author Correction: Genetic variation in the human leukocyte antigen region confers susceptibility to Clostridioides difficile infection.
Kathleen Ferar, Taryn O Hall, Dana C Crawford, Robb Rowley, Benjamin A Satterfield, John J Connolly

Sci Rep· November 2023

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Genetic variation in the human leukocyte antigen region confers susceptibility to Clostridioides difficile infection.
Kathleen Ferar, Taryn O Hall, Dana C Crawford, Robb Rowley, Benjamin A Satterfield, John J Connolly

Sci Rep· October 2023

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Education and electronic medical records and genomics network, challenges, and lessons learned from a large-scale clinical trial using polygenic risk scores.
John J Connolly, Eta S Berner, Maureen Smith, Samuel Levy, Shannon Terek

Genet Med· September 2023

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Studying the impact of translational genomic research: Lessons from eMERGE.
Ellen Wright Clayton, Maureen E Smith, Katherine C Anderson, Wendy K Chung, John J Connolly

Am J Hum Genet· July 2023

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Selection, optimization, and validation of ten chronic disease polygenic risk scores for clinical implementation in diverse populations.
Niall J Lennon, Leah C Kottyan, Christopher Kachulis, Noura Abul-Husn, Josh Arias, John J Connolly

medRxiv· June 2023

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Single Cell Transcriptome Analysis of Peripheral Blood Mononuclear Cells in Freshly Isolated versus Stored Blood Samples.
Hui-Qi Qu, Charlly Kao, James Garifallou, Fengxiang Wang, James Snyder, John J Connolly

Genes (Basel)· January 2023

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Trans-ethnic Polygenic Risk Scores for Body Mass Index: An International Hundred K+ Cohorts Consortium Study.
Huiqi Qu, John J Connolly, Peter Kraft, Jirong Long, Alexandre Pereira

medRxiv· January 2023

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Attitudes among Parents towards Return of Disease-Related Polygenic Risk Scores (PRS) for Their Children.
Shannon Terek, Maya C Del Rosario, Heather S Hain, John J Connolly, Meckenzie A Behr

J Pers Med· November 2022

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