Publications by authors named "Jonathan A. Ellman"

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Biocatalytic Enantioselective Oxidation of -Acyl--Methyl Sulfenamides for the Asymmetric Synthesis of -Methyl Sulfoximines.
Shivani Patel, James D Finnigan, Jesmine Lim, Nathaniel S Greenwood, Jonathan A Ellman

Org Lett· December 2025

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Studies on the Mechanism of Styrene Elimination from Sulfilimines: Hammett and Kinetic Isotope Effect Analysis and Computation.
Shivani Patel, Nicholas P Cerny, Lucas G Zimmer, Shuming Chen, Jonathan A Ellman

J Org Chem· August 2025

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Ruthenium-Catalyzed Enantioselective Alkylation of Sulfenamides: A General Approach for the Synthesis of Drug Relevant -Methyl and -Cyclopropyl Sulfoximines.
Zachary W Boyer, Na Yeon Kwon, Jonathan A Ellman

J Am Chem Soc· May 2025

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Docking 14 Million Virtual Isoquinuclidines against the μ and κ Opioid Receptors Reveals Dual Antagonists-Inverse Agonists with Reduced Withdrawal Effects.
Seth F Vigneron, Shohei Ohno, Joao Braz, Joseph Y Kim, Oh Sang Kweon, Jonathan A Ellman

ACS Cent Sci· May 2025

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Sulfilimines from a Medicinal Chemist's Perspective: Physicochemical and in Vitro Parameters Relevant for Drug Discovery.
Nathaniel S Greenwood, Zachary W Boyer, Jonathan A Ellman, Christian Gnamm

J Med Chem· February 2025

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Docking 14 million virtual isoquinuclidines against the mu and kappa opioid receptors reveals dual antagonists-inverse agonists with reduced withdrawal effects.
Seth F Vigneron, Shohei Ohno, Joao Braz, Joseph Y Kim, Oh Sang Kweon, Jonathan A Ellman

bioRxiv· January 2025

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C-H Activation and Sequential Addition to Dienes and Imines: Synthesis of Amines with -Quaternary Centers and Mechanistic Studies on the Complex Interplay Between the Catalyst and Three Reactants.
Ramsey M Goodner, Daniel S Brandes, Gabriel N Morais, Qiyuan Tao, Joseph P Tassone, Jonathan A Ellman

ACS Catal· December 2024

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Synthesis of α-Quaternary Amides via Cp*Co(III)-Catalyzed Sequential C-H Bond Addition to 1,3-Dienes and Isocyanates.
Jihyeon Yeo, Joseph P Tassone, Jonathan A Ellman

Org Lett· November 2024

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Enantioselective S-Alkylation of Sulfenamides by Phase-Transfer Catalysis.
Andrew T Champlin, Na Yeon Kwon, Jonathan A Ellman

Angew Chem Int Ed Engl· October 2024

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Synthesis of Monodehydro-Diketopiperazines Enabled by Cp*Rh(III)-Catalyzed Amine-Directed N-H Functionalization.
Jenna C Molas, Emily M Poag, Jonathan A Ellman

Org Lett· October 2024

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Disulfide Tethering to Map Small Molecule Binding Sites Transcriptome-wide.
Michelle H Moon, Isaac W Vock, Andrew D Streit, Leah J Connor, Julia Senkina, Jonathan A Ellman

ACS Chem Biol· September 2024

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Rh(II)-Catalyzed Enantioselective -Alkylation of Sulfenamides with Acceptor-Acceptor Diazo Compounds Enables the Synthesis of Sulfoximines Displaying Diverse Functionality.
Shivani Patel, Nathaniel S Greenwood, Brandon Q Mercado, Jonathan A Ellman

Org Lett· July 2024

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Copper-Catalyzed Three-Component Synthesis of Highly Substituted Morpholines.
Duc Chu, Adam J Zoll, Jonathan A Ellman

Org Lett· June 2024

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Correction to "Catalytic Enantioselective Sulfur Alkylation of Sulfenamides for the Asymmetric Synthesis of Sulfoximines".
Nathaniel S Greenwood, Andrew T Champlin, Jonathan A Ellman

J Am Chem Soc· February 2024

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Synthesis of N-Acylsulfenamides from (Hetero)Aryl Iodides and Boronic Acids by One-Pot Sulfur-Arylation and Dealkylation.
Nathaniel S Greenwood, Nicholas P Cerny, Anthony P Deziel, Jonathan A Ellman

Angew Chem Int Ed Engl· January 2024

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Visible-Light-Mediated, Diastereoselective Epimerization of Exocyclic Amines.
María A Vargas-Rivera, Aidan S Liu, Jonathan A Ellman

Org Lett· December 2023

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Synthesis of -Acylsulfenamides from Amides and -Thiosuccinimides.
Jessica T Liu, Daniel S Brandes, Nathaniel S Greenwood, Jonathan A Ellman

Synthesis (Stuttg)· August 2023

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Preparation of Sulfilimines by Sulfur-Alkylation of -Acyl Sulfenamides with Alkyl Halides.
Andrew T Champlin, Jonathan A Ellman

J Org Chem· June 2023

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Sulfur-Arylation of Sulfenamides via Ullmann-Type Coupling with (Hetero)aryl Iodides.
Nathaniel S Greenwood, Jonathan A Ellman

Org Lett· June 2023

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Stereospecific Synthesis of Unprotected, α,β-Disubstituted Tryptamines and Phenethylamines from 1,2-Disubstituted Alkenes via a One-Pot Reaction Sequence.
Duc Chu, Jonathan A Ellman

Org Lett· May 2023

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Sulfur-Arylation of Sulfenamides via Chan-Lam Coupling with Boronic Acids: Access to High Oxidation State Sulfur Pharmacophores.
Nathaniel S Greenwood, Jonathan A Ellman

Org Lett· April 2023

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Imine Directed Cp*Rh -Catalyzed N-H Functionalization and Annulation with Amino Amides, Aldehydes, and Diazo Compounds.
Adam J Zoll, Jenna C Molas, Brandon Q Mercado, Jonathan A Ellman

Angew Chem Int Ed Engl· January 2023

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Three-component carboformylation: α-quaternary aldehyde synthesis Co(iii)-catalysed sequential C-H bond addition to dienes and acetic formic anhydride.
Joseph P Tassone, Jihyeon Yeo, Jonathan A Ellman

Chem Sci· December 2022

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Bespoke library docking for 5-HT receptor agonists with antidepressant activity.
Anat Levit Kaplan, Danielle N Confair, Kuglae Kim, Ximena Barros-Álvarez, Ramona M Rodriguiz, Jonathan A Ellman

Nature· October 2022

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Visible Light-Mediated, Diastereoselective Epimerization of Morpholines and Piperazines to More Stable Isomers.
Zican Shen, María A Vargas-Rivera, Elizabeth L Rigby, Shuming Chen, Jonathan A Ellman

ACS Catal· October 2022

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