Publications by authors named "Jordan Frank"

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Large language model processing capabilities of ChatGPT 4.0 to generate molecular tumor board recommendations-a critical evaluation on real world data.
Maximilian Schmutz, Sebastian Sommer, Julia Sander, David Graumann, Johannes Raffler, Frank Jordan

Oncologist· October 2025

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Comparison of Three Chimeric Zika Vaccine Prototypes Developed on the Genetic Background of the Clinically Proven Live-Attenuated Japanese Encephalitis Vaccine SA-14-2.
Byung-Hak Song, Jordan C Frank, Sang-Im Yun, Justin G Julander, Jeffrey B Mason

Int J Mol Sci· December 2024

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The WERA cancer center matrix: Strategic management of patient access to precision oncology in a large and mostly rural area of Germany.
Markus Krebs, Florian Haller, Silvia Spörl, Elena Gerhard-Hartmann, Kirsten Utpatel, Frank Jordan

Eur J Cancer· August 2024

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Individualized targeted treatment in a case of a rare TFG::ROS1 fusion positive inflammatory myofibroblastic tumor (IMT).
Sebastian Sommer, Maximilian Schmutz, Tina Schaller, Patrick Mayr, Sebastian Dintner, Frank Jordan

Cancer Rep (Hoboken)· January 2024

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Mice as an Animal Model for Japanese Encephalitis Virus Research: Mouse Susceptibility, Infection Route, and Viral Pathogenesis.
Jordan C Frank, Byung-Hak Song, Young-Min Lee

Pathogens· May 2023

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Alterations in Natural Killer Cells in Colorectal Cancer Patients with Stroma AReactive Invasion Front Areas (SARIFA).
Nic G Reitsam, Bruno Märkl, Sebastian Dintner, Eva Sipos, Przemyslaw Grochowski, Frank Jordan

Cancers (Basel)· February 2023

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Probing the E1o-E2o and E1a-E2o Interactions in Binary Subcomplexes of the Human 2-Oxoglutarate Dehydrogenase and 2-Oxoadipate Dehydrogenase Complexes by Chemical Cross-Linking Mass Spectrometry and Molecular Dynamics Simulation.
Oliver Ozohanics, Xu Zhang, Natalia S Nemeria, Attila Ambrus, Frank Jordan

Int J Mol Sci· February 2023

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Identification of Disparities in Personalized Cancer Care-A Joint Approach of the German WERA Consortium.
Florian Lüke, Florian Haller, Kirsten Utpatel, Markus Krebs, Norbert Meidenbauer, Frank Jordan

Cancers (Basel)· October 2022

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Restoring Immune Mediated Disease Control by Ipilimumab Re-exposition in a Heavily pretreated Patient With MSI-H mCRC.
Frank Jordan, Martin Trepel, Rainer Claus

Clin Colorectal Cancer· September 2022

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Development and characterization of type I interferon receptor knockout sheep: A model for viral immunology and reproductive signaling.
Christopher J Davies, Zhiqiang Fan, Kira P Morgado, Ying Liu, Misha Regouski, Jordan C Frank

Front Genet· September 2022

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Structures of the Most Twisted Thioamide and Selenoamide: Effect of Higher Chalcogens of Twisted Amides on N-C(X) Resonance.
Qun Zhao, Guangchen Li, Pradeep Nareddy, Frank Jordan, Roger Lalancette

Angew Chem Int Ed Engl· August 2022

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Functional Versatility of the Human 2-Oxoadipate Dehydrogenase in the L-Lysine Degradation Pathway toward Its Non-Cognate Substrate 2-Oxopimelic Acid.
Natalia S Nemeria, Balint Nagy, Roberto Sanchez, Xu Zhang, João Leandro, Frank Jordan

Int J Mol Sci· July 2022

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E. coli and the etiology of human PBC: Antimitochondrial antibodies and spreading determinants.
Yao Yang, Jinjung Choi, Ying Chen, Pietro Invernizzi, Guoxiang Yang, Frank Jordan

Hepatology· February 2022

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Structure of the dihydrolipoamide succinyltransferase (E2) component of the human alpha-ketoglutarate dehydrogenase complex (hKGDHc) revealed by cryo-EM and cross-linking mass spectrometry: Implications for the overall hKGDHc structure.
Balint Nagy, Martin Polak, Oliver Ozohanics, Zsofia Zambo, Eszter Szabo, Frank Jordan

Biochim Biophys Acta Gen Subj· June 2021

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A Retrospective 5-Year Single Center Study Highlighting the Risk of Cancer Predisposition in Adolescents and Young Adults.
Frank Jordan, Simon Huber, Sebastian Sommer, Gerhard Schenkirsch, Michael C Frühwald

Cancers (Basel)· June 2021

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Toward an Understanding of the Structural and Mechanistic Aspects of Protein-Protein Interactions in 2-Oxoacid Dehydrogenase Complexes.
Natalia S Nemeria, Xu Zhang, Joao Leandro, Jieyu Zhou, Luying Yang, Frank Jordan

Life (Basel)· April 2021

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Inhibition and Crystal Structure of the Human DHTKD1-Thiamin Diphosphate Complex.
João Leandro, Susmita Khamrui, Hui Wang, Chalada Suebsuwong, Natalia S Nemeria, Frank Jordan

ACS Chem Biol· August 2020

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Structure-function analyses of the G729R 2-oxoadipate dehydrogenase genetic variant associated with a disorder of l-lysine metabolism.
Xu Zhang, Natalia S Nemeria, João Leandro, Sander Houten, Michael Lazarus, Frank Jordan

J Biol Chem· June 2020

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DHTKD1 and OGDH display substrate overlap in cultured cells and form a hybrid 2-oxo acid dehydrogenase complex in vivo.
João Leandro, Tetyana Dodatko, Jan Aten, Natalia S Nemeria, Xu Zhang, Frank Jordan

Hum Mol Genet· May 2020

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Development, Characterization, and Application of Two Reporter-Expressing Recombinant Zika Viruses.
Sang-Im Yun, Byung-Hak Song, Michael E Woolley, Jordan C Frank, Justin G Julander

Viruses· May 2020

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Exclusive neuronal detection of KGDHC-specific subunits in the adult human brain cortex despite pancellular protein lysine succinylation.
Arpad Dobolyi, Attila Bago, Miklos Palkovits, Natalia S Nemeria, Frank Jordan

Brain Struct Funct· March 2020

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Active Site Histidines Link Conformational Dynamics with Catalysis on Anti-Infective Target 1-Deoxy-d-xylulose 5-Phosphate Synthase.
Alicia A DeColli, Xu Zhang, Kathryn L Heflin, Frank Jordan, Caren L Freel Meyers

Biochemistry· December 2019

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Human 2-Oxoglutarate Dehydrogenase and 2-Oxoadipate Dehydrogenase Both Generate Superoxide/HO in a Side Reaction and Each Could Contribute to Oxidative Stress in Mitochondria.
Frank Jordan, Natalia Nemeria, Gary Gerfen

Neurochem Res· October 2019

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Underlying molecular alterations in human dihydrolipoamide dehydrogenase deficiency revealed by structural analyses of disease-causing enzyme variants.
Eszter Szabo, Piotr Wilk, Balint Nagy, Zsofia Zambo, David Bui, Frank Jordan

Hum Mol Genet· October 2019

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A multipronged approach unravels unprecedented protein-protein interactions in the human 2-oxoglutarate dehydrogenase multienzyme complex.
Jieyu Zhou, Luying Yang, Oliver Ozohanics, Xu Zhang, Junjie Wang, Frank Jordan

J Biol Chem· December 2018

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