Publications by authors named "Jose Lizcano"

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Understanding Ibrilatazar's mechanism of action: Addressing concerns about autophagy in cancer Therapy.
Joaquim Bosch-Barrera, Héctor Pérez-Montoyo, Carles Domènech, Jose M Lizcano

Lung Cancer· May 2025

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ENDOLUNG trial, part II. A phase II study of the Akt/mTOR inhibitor and autophagy inducer ibrilatazar (ABTL0812) in combination with paclitaxel/carboplatin in patients with squamous non-small cell lung cancer.
Joaquim Bosch-Barrera, Purificación Estévez-García, Paloma Martín-Martorell, Renaud Sabatier, Ernest Nadal, Jose M Lizcano

Lung Cancer· March 2025

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Chitinase 3-like 1 is neurotoxic in multiple sclerosis patient-derived cortical neurons.
Rucsanda Pinteac, Jordi Soriano, Clara Matute-Blanch, José M Lizcano, Anna Duarri

Clin Transl Med· December 2024

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ENDOLUNG trial. A phase 1/2 study of the Akt/mTOR inhibitor and autophagy inducer Ibrilatazar (ABTL0812) in combination with paclitaxel/carboplatin in patients with advanced/recurrent endometrial cancer.
Alexandra Leary, Purificación Estévez-García, Renaud Sabatier, Isabelle Ray-Coquard, Margarita Romeo, Jose M Lizcano

BMC Cancer· July 2024

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Correction: ENDOLUNG trial. A phase 1/2 study of the Akt/mTOR inhibitor and autophagy inducer Ibrilatazar (ABTL0812) in combination with paclitaxel/carboplatin in patients with advanced/recurrent endometrial cancer : Alexandra Leary.
Alexandra Leary, Purificación Estévez-García, Renaud Sabatier, Isabelle Ray-Coquard, Margarita Romeo, Jose M Lizcano

BMC Cancer· July 2024

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TRIB3 silencing promotes the downregulation of Akt pathway and PAX3-FOXO1 in high-risk rhabdomyosarcoma.
Gabriel Gallo-Oller, Guillem Pons, Júlia Sansa-Girona, Natalia Navarro, Patricia Zarzosa, José M Lizcano

Exp Hematol Oncol· April 2024

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MAP kinase ERK5 modulates cancer cell sensitivity to extrinsic apoptosis induced by death-receptor agonists.
Sergio Espinosa-Gil, Saska Ivanova, Elisenda Alari-Pahissa, Melek Denizli, Beatriz Villafranca-Magdalena, José Miguel Lizcano

Cell Death Dis· November 2023

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The ERK5/NF-κB signaling pathway targets endometrial cancer proliferation and survival.
Nora Diéguez-Martínez, Sergio Espinosa-Gil, Guillermo Yoldi, Elisabet Megías-Roda, Idoia Bolinaga-Ayala, Jose M Lizcano

Cell Mol Life Sci· September 2022

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ABTL0812 enhances antitumor effect of paclitaxel and reverts chemoresistance in triple-negative breast cancer models.
Emma Polonio-Alcalá, Sònia Solé-Sánchez, Pau Muñoz-Guardiola, Elisabet Megías-Roda, Héctor Perez-Montoyo, Jose Miguel Lizcano

Cancer Commun (Lond)· June 2022

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Methuosis Contributes to Jaspine-B-Induced Cell Death.
Núria Bielsa, Mireia Casasampere, Jose Luis Abad, Carlos Enrich, Antonio Delgado, Jose M Lizcano

Int J Mol Sci· June 2022

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An ERK5-KLF2 signalling module regulates early embryonic gene expression and telomere rejuvenation in stem cells.
Helen A Brown, Charles A C Williams, Houjiang Zhou, Diana Rios-Szwed, Rosalia Fernandez-Alonso, Jose M Lizcano

Biochem J· December 2021

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ERK5 Inhibition Induces Autophagy-Mediated Cancer Cell Death by Activating ER Stress.
Andrés Gámez-García, Idoia Bolinaga-Ayala, Guillermo Yoldi, Sergio Espinosa-Gil, Nora Diéguez-Martínez, Jose M Lizcano

Front Cell Dev Biol· November 2021

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GRP78 Overexpression Triggers PINK1-IPR-Mediated Neuroprotective Mitophagy.
Tatiana Leiva-Rodríguez, David Romeo-Guitart, Mireia Herrando-Grabulosa, Pau Muñoz-Guardiola, Miriam Polo, Jose Miguel Lizcano

Biomedicines· August 2021

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The anti-cancer drug ABTL0812 induces ER stress-mediated cytotoxic autophagy by increasing dihydroceramide levels in cancer cells.
Pau Muñoz-Guardiola, Josefina Casas, Elisabet Megías-Roda, Sònia Solé, Héctor Perez-Montoyo, Jose M Lizcano

Autophagy· June 2021

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A first-in-human phase I/Ib dose-escalation clinical trial of the autophagy inducer ABTL0812 in patients with advanced solid tumours.
Laura Vidal, Ivan Victoria, Lydia Gaba, Marta Gil Martín, Mercè Brunet, José Miguel Lizcano

Eur J Cancer· March 2021

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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition).
Daniel J Klionsky, Amal Kamal Abdel-Aziz, Sara Abdelfatah, Mahmoud Abdellatif, Asghar Abdoli, Jose M Lizcano

Autophagy· January 2021

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The antitumour drug ABTL0812 impairs neuroblastoma growth through endoplasmic reticulum stress-mediated autophagy and apoptosis.
Laia París-Coderch, Aroa Soriano, Carlos Jiménez, Tatiana Erazo, Pau Muñoz-Guardiola, José M Lizcano

Cell Death Dis· September 2020

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The novel proautophagy anticancer drug ABTL0812 potentiates chemotherapy in adenocarcinoma and squamous nonsmall cell lung cancer.
Anna López-Plana, Patricia Fernández-Nogueira, Pau Muñoz-Guardiola, Sònia Solé-Sánchez, Elisabet Megías-Roda, Jose M Lizcano

Int J Cancer· August 2020

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STK11 (LKB1) missense somatic mutant isoforms promote tumor growth, motility and inflammation.
Paula Granado-Martínez, Sara Garcia-Ortega, Elena González-Sánchez, Kimberley McGrail, Rafael Selgas, José M Lizcano

Commun Biol· July 2020

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Genetic manipulation of LKB1 elicits lethal metastatic prostate cancer.
Ivana Hermanova, Patricia Zúñiga-García, Alfredo Caro-Maldonado, Sonia Fernandez-Ruiz, Fernando Salvador, Jose M Lizcano

J Exp Med· June 2020

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Discovery of a selective inhibitor of doublecortin like kinase 1.
Fleur M Ferguson, Behnam Nabet, Srivatsan Raghavan, Yan Liu, Alan L Leggett, Jose M Lizcano

Nat Chem Biol· June 2020

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The peroxisomal fatty acid transporter ABCD1/PMP-4 is required in the C. elegans hypodermis for axonal maintenance: A worm model for adrenoleukodystrophy.
Andrea Coppa, Sanjib Guha, Stéphane Fourcade, Janani Parameswaran, Montserrat Ruiz, Jose Miguel Lizcano

Free Radic Biol Med· May 2020

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SUMOylation Is Required for ERK5 Nuclear Translocation and ERK5-Mediated Cancer Cell Proliferation.
Tatiana Erazo, Sergio Espinosa-Gil, Nora Diéguez-Martínez, Néstor Gómez, Jose M Lizcano

Int J Mol Sci· March 2020

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Characterization of the TLR Family in and Discovery of a Novel TLR22-Like Involved in dsRNA Recognition in Amphioxus.
Jie Ji, David Ramos-Vicente, Enrique Navas-Pérez, Carlos Herrera-Úbeda, José Miguel Lizcano

Front Immunol· October 2019

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Therapeutic potential of the new TRIB3-mediated cell autophagy anticancer drug ABTL0812 in endometrial cancer.
Isidre Felip, Cristian Pablo Moiola, Cristina Megino-Luque, Carlos Lopez-Gil, Silvia Cabrera, José Miguel Lizcano

Gynecol Oncol· May 2019

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