Publications by authors named "Joseph Loo"

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GFAP Degradation in TBI: Linking Novel Modified Products to Astrocyte Pathology and Patient Outcome.
Ina B Wanner, Julia Halford, Jonathan Lopez, Sean Shen, Yu Chen, Rachel R Loo, Joseph A Loo

bioRxiv· November 2025

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Structural basis for L-isoaspartyl-containing protein recognition by the human PCMTD1 cullin-RING E3 ubiquitin ligase.
Eric Z Pang, Boyu Zhao, Cameron Flowers, Elizabeth Oroudjeva, Jasmine B Winter, Joseph A Loo

J Biol Chem· November 2025

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The 3rd International Top-Down Proteomics Symposium Brings Proteoform Biology to the Forefront of Proteomics.
Paul O Danis, Joseph A Loo, Hartmut Schlüter

J Am Soc Mass Spectrom· November 2025

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Allosteric Modulation of Pathological Ataxin-3 Aggregation: A Path to Spinocerebellar Ataxia Type-3 Therapies.
Alexandra Silva, Sara Duarte-Silva, Pedro M Martins, Beatriz Rodrigues, Débora Serrenho, Joseph A Loo

Adv Sci (Weinh)· November 2025

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Structural basis of heme scavenging by the ChtA and HtaA hemophores in Corynebacterium diphtheriae.
Jordan Ford, Andrew K Goring, Yuri Lee, Megan Chen, Brendan J Mahoney, Joseph A Loo

J Biol Chem· October 2025

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Retention and Rearrangement of Membrane Protein Complexes' Higher Order Structure by Collisionally Activated Dissociation- and Electron Capture Dissociation-Mass Spectrometry.
Jessie Le, Wonhyeuk Jung, Mark A Arbing, Pascal F Egea, Rachel R Ogorzalek Loo, Joseph A Loo

J Am Chem Soc· October 2025

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Leveraging bioorthogonal conjugation for alpha synuclein fibril surveillance.
Rebecca A Jenkins, Samantha Wu, Gretchen Fujimura, Andrés Heredia, Cameron W Flowers, Joseph A Loo

bioRxiv· September 2025

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Combining MicroED and native mass spectrometry for structural discovery of enzyme-small molecule complexes.
Niko W Vlahakis, Cameron W Flowers, Mengting Liu, Matthew P Agdanowski, Samuel Johnson, Joseph A Loo

Proc Natl Acad Sci U S A· August 2025

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Native Top-Down Mass Spectrometry Characterization of Model Integral Membrane Protein Bacteriorhodopsin.
Jessie Le, Joseph A Loo

J Am Soc Mass Spectrom· May 2025

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Structural basis for L-isoaspartyl-containing protein recognition by the PCMTD1 cullin-RING E3 ubiquitin ligase.
Eric Z Pang, Boyu Zhao, Cameron Flowers, Elizabeth Oroudjeva, Jasmine B Winter, Joseph A Loo

bioRxiv· May 2025

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Evolution of Mass Spectrometers for High / Biological Ion Formation, Transmission, Analysis and Detection: A Personal Perspective.
Iain D G Campuzano, Joseph A Loo

J Am Soc Mass Spectrom· April 2025

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Copper-dependent halogenase catalyses unactivated C-H bond functionalization.
Chen-Yu Chiang, Masao Ohashi, Jessie Le, Pan-Pan Chen, Qingyang Zhou, Joseph A Loo

Nature· February 2025

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Combining MicroED and native mass spectrometry for structural discovery of enzyme-biosynthetic inhibitor complexes.
Niko W Vlahakis, Cameron W Flowers, Mengting Liu, Matthew Agdanowski, Samuel Johnson, Joseph A Loo

bioRxiv· February 2025

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The Exoproteome and Surfaceome of Toxigenic 1737 and Its Response to Iron Restriction and Growth on Human Hemoglobin.
Andrew K Goring, Scott Hale, Poojita Dasika, Yu Chen, Robert T Clubb, Joseph A Loo

J Proteome Res· January 2025

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Allosteric Modulation of Pathological Ataxin-3 Aggregation: A Path to Spinocerebellar Ataxia Type-3 Therapies.
Alexandra Silva, Sara Duarte-Silva, Pedro M Martins, Beatriz Rodrigues, Débora Serrenho, Joseph A Loo

bioRxiv· January 2025

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Top-down mass spectrometry of native proteoforms and their complexes: a community study.
Tanja Habeck, Kyle A Brown, Benjamin Des Soye, Carter Lantz, Mowei Zhou, Joseph A Loo

Nat Methods· December 2024

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Composition and in situ structure of the cell envelope and surface layer.
Hui Wang, Jiayan Zhang, Shiqing Liao, Anne M Henstra, Deborah Leon, Joseph A Loo, Rachel R Ogorzalek Loo

Sci Adv· December 2024

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Are Internal Fragments Observable in Electron Based Top-Down Mass Spectrometry?
Neven N Mikawy, Carolina Rojas Ramírez, Steven A DeFiglia, Carson W Szot, Jessie Le, Joseph A Loo

Mol Cell Proteomics· September 2024

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Insight into the autoproteolysis mechanism of the RsgI9 anti-σ factor from Clostridium thermocellum.
Allen Takayesu, Brendan J Mahoney, Andrew K Goring, Tobie Jessup, Rachel R Ogorzalek Loo, Joseph A Loo

Proteins· August 2024

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Top-down proteomics.
David S Roberts, Joseph A Loo, Yury O Tsybin, Xiaowen Liu, Si Wu

Nat Rev Methods Primers· June 2024

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Ultrafast Au(III)-Mediated Arylation of Cysteine.
Evan A Doud, James A R Tilden, Joseph W Treacy, Elaine Y Chao, Hayden R Montgomery, Joseph A Loo

J Am Chem Soc· May 2024

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The Annual ASMS Conference: Relax, and Give Us Your Feedback.
Joseph A Loo

J Am Soc Mass Spectrom· May 2024

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D-peptide-magnetic nanoparticles fragment tau fibrils and rescue behavioral deficits in a mouse model of Alzheimer's disease.
Ke Hou, Hope Pan, Hedieh Shahpasand-Kroner, Carolyn Hu, Romany Abskharon, Joseph A Loo

Sci Adv· May 2024

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Internal Fragments Enhance Middle-Down Mass Spectrometry Structural Characterization of Monoclonal Antibodies and Antibody-Drug Conjugates.
Benqian Wei, Carter Lantz, Rachel R Ogorzalek Loo, Iain D G Campuzano, Joseph A Loo

Anal Chem· February 2024

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Detection of Lipid-Bound Bacteriorhodopsin Trimer Complex Directly from Purple Membrane by Native Mass Spectrometry.
Jessie Le, Joseph A Loo

J Am Soc Mass Spectrom· December 2023

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