Publications by authors named "Joseph Topczewski"

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Academia or Industry: Lessons on Choosing Career Paths─There May Be More Than One Fork in the Road Ahead.
Donna G Blackmond, Marion Emmert, Donna M Huryn, Michael L Neidig, Thomas Schaub, Joseph J Topczewski

Org Lett· April 2024

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Combined Experimental and Computational Mechanistic Investigation of the Palladium-Catalyzed Decarboxylative Cross-Coupling of Sodium Benzoates with Chloroarenes.
Jenna N Humke, Ryan A Daley, Aaron S Morrenzin, Sharon R Neufeldt, Joseph J Topczewski

J Org Chem· September 2021

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4-Methyl-1,2,3-Triazoles as -Acetyl-Lysine Mimics Afford Potent BET Bromodomain Inhibitors with Improved Selectivity.
Huarui Cui, Angela S Carlson, Mary A Schleiff, Anand Divakaran, Jorden A Johnson, Joseph J Topczewski

J Med Chem· July 2021

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Silver Mediated Banert Cascade with Carbon Nucleophiles.
Juliana R Alexander, Paul V Kevorkian, Joseph J Topczewski

Org Lett· April 2021

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Enantioselective Nickel-Catalyzed Alkyne-Azide Cycloaddition by Dynamic Kinetic Resolution.
En-Chih Liu, Joseph J Topczewski

J Am Chem Soc· April 2021

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A cascade reaction of cinnamyl azides with vinyl sulfones directly generates dihydro-pyrrolo-pyrazole heterocycles.
Angela S Carlson, Alexandru M Petre, Joseph J Topczewski

Tetrahedron Lett· March 2021

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Enhanced Affinity for 3-Amino-Chromane-Derived σ Receptor Ligands.
Matthew R Porter, Haiyan Xiao, Sanjay Maity, Nora Vail, Sylvia B Smith, Joseph J Topczewski

ACS Omega· December 2020

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Gold Catalyzed Decarboxylative Cross-Coupling of Iodoarenes.
Ryan A Daley, Aaron S Morrenzin, Sharon R Neufeldt, Joseph J Topczewski

J Am Chem Soc· July 2020

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Ti-catalyzed ring-opening oxidative amination of methylenecyclopropanes with diazenes.
Evan P Beaumier, Amy A Ott, Xuelan Wen, Zachary W Davis-Gilbert, T Alexander Wheeler, Joseph J Topczewski

Chem Sci· June 2020

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A Cascade Reaction of Cinnamyl Azides with Acrylates Directly Generates Tetrahydro-Pyrrolo-Pyrazole Heterocycles.
Angela S Carlson, En-Chih Liu, Joseph J Topczewski

J Org Chem· May 2020

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Divergent Mechanisms of the Banert Cascade with Propargyl Azides.
Juliana R Alexander, Mary H Packard, Alanna M Hildebrandt, Amy A Ott, Joseph J Topczewski

J Org Chem· March 2020

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Gram-Scale Synthesis of 2,5-Difluoro-7,7,8,8-tetracyanoquinodimethane (F-TCNQ).
En-Chih Liu, Joseph J Topczewski

J Org Chem· March 2020

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Double-click enables synthesis of chemical libraries for drug discovery.
Joseph J Topczewski, En-Chih Liu

Nature· October 2019

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3-Amino-chromanes and Tetrahydroquinolines as Selective 5-HT, 5-HT, or σ Receptor Ligands.
Matthew R Porter, Haiyan Xiao, Jing Wang, Sylvia B Smith, Joseph J Topczewski

ACS Med Chem Lett· October 2019

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Systematically Mitigating the p38α Activity of Triazole-based BET Inhibitors.
Angela S Carlson, Huarui Cui, Anand Divakaran, Jorden A Johnson, Ryan M Brunner, Joseph J Topczewski

ACS Med Chem Lett· September 2019

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Kinetic Resolution of Cyclic Secondary Azides, Using an Enantioselective Copper-Catalyzed Azide-Alkyne Cycloaddition.
Juliana R Alexander, Amy A Ott, En-Chih Liu, Joseph J Topczewski

Org Lett· June 2019

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Additive-Free Palladium-Catalyzed Decarboxylative Cross-Coupling of Aryl Chlorides.
Ryan A Daley, En-Chih Liu, Joseph J Topczewski

Org Lett· June 2019

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Allylic azides: synthesis, reactivity, and the Winstein rearrangement.
Angela S Carlson, Joseph J Topczewski

Org Biomol Chem· May 2019

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Enantioselective Copper Catalyzed Alkyne-Azide Cycloaddition by Dynamic Kinetic Resolution.
En-Chih Liu, Joseph J Topczewski

J Am Chem Soc· April 2019

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On the Winstein rearrangement: equilibrium and mechanism.
Amy A Ott, Joseph J Topczewski

ARKIVOC· March 2019

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Palladium-catalyzed salt-free double decarboxylative aryl allylation.
Ryan A Daley, Joseph J Topczewski

Org Biomol Chem· February 2019

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Catalytic Racemization of Activated Organic Azides.
Amy A Ott, Joseph J Topczewski

Org Lett· November 2018

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Molecular Basis for the N-Terminal Bromodomain-and-Extra-Terminal-Family Selectivity of a Dual Kinase-Bromodomain Inhibitor.
Anand Divakaran, Siva K Talluri, Alex M Ayoub, Neeraj K Mishra, Huarui Cui, Joseph J Topczewski

J Med Chem· October 2018

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Evidence for a Sigmatropic and an Ionic Pathway in the Winstein Rearrangement.
Amy A Ott, Mary H Packard, Manuel A Ortuño, Alayna Johnson, Victoria P Suding, Joseph J Topczewski

J Org Chem· August 2018

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"It's a (Kinetic) Trap!" - Selectively Differentiating Allylic Azide Isomers.
Joseph J Topczewski, Matthew R Porter

Synlett· July 2018

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