Publications by authors named "Joshua Bis"

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Adjustment for Genotype Imputation Uncertainty Corrects for Inflated Type I Error in Family-Based Association Testing.
Tyler R C Day, Joshua C Bis, Nicola Chapman, Alejandro Q Nato, Andrea R V R Horimoto

Genet Epidemiol· December 2025

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Proteogenomics in cerebrospinal fluid and plasma reveals new biological fingerprint of cerebral small vessel disease.
Ilana Caro, Daniel Western, Shinichi Namba, Na Sun, Shuji Kawaguchi, Joshua C Bis

Nat Aging· December 2025

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Domain mapping of disease mutations reveals pathogenic SORL1 variants in Alzheimer's disease.
Olav M Andersen, Matthijs W J de Waal, Giulia Monti, Niccolo Tesi, Anne Mette G Jensen, Joshua C Bis

Mol Neurodegener· December 2025

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Human plasma proteomic profile of clonal hematopoiesis.
Zhi Yu, Amélie Vromman, Ngoc Quynh H Nguyen, Art Schuermans, Linke Li, Joshua C Bis

Nat Commun· November 2025

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Associations of Immune Cell Subsets With Coronary Artery Calcium Incidence and Progression in the Multi-Ethnic Study of Atherosclerosis.
Riddhi D Patel, Petra Buzkova, Sally Huber, Alan Landay, Matthew Budoff, Joshua C Bis

J Am Heart Assoc· October 2025

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Polygenic prediction of body mass index and obesity through the life course and across ancestries.
Roelof A J Smit, Kaitlin H Wade, Qin Hui, Joshua D Arias, Xianyong Yin, Joshua C Bis

Nat Med· September 2025

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Whole genome sequence analysis of low-density lipoprotein cholesterol across 246 K individuals.
Margaret Sunitha Selvaraj, Xihao Li, Zilin Li, Eric Van Buren, Sara Haidermota, Joshua C Bis

Genome Biol· September 2025

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Association of genetic scores related to insulin resistance with neurological outcomes in ancestrally diverse cohorts from the Trans-Omics for Precision Medicine (TOPMed) program.
Chloé Sarnowski, Yixin Zhang, Farah Ammous, Lincoln M P Shade, Daniel DiCorpo, Joshua C Bis

Commun Biol· September 2025

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Deep Learning Prediction of Left Atrial Structure and Function from 12-lead Electrocardiograms.
Jennifer A Brody, Vidhushei Yogeswaran, Kerri L Wiggins, Colleen M Sitlani, Joshua C Bis

medRxiv· September 2025

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Epigenetic mechanisms underlying variation of IL-6, a well-established inflammation biomarker and risk factor for cardiovascular disease.
Jessica I Lundin, Ulrike Peters, Yao Hu, Farah Ammous, Emelia J Benjamin, Joshua C Bis

Atherosclerosis· August 2025

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Plasma TAR DNA-binding protein 43 (TDP-43) levels in a population-based cohort of older adults: The cardiovascular health study.
Alison E Fohner, Colleen M Sitlani, Suman Jayadev, Joshua C Bis, Emily H Trittschuh

J Alzheimers Dis· June 2025

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Whole genome sequence association analysis of brain structural volume measures in the NHLBI TOPMed Program highlights novel loci in diverse participants.
Lincoln Mp Shade, Mohsen Sharifitabar, Alexa Beiser, Claudia L Satizabal, Thomas H Mosley, Joshua C Bis

medRxiv· June 2025

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Frequency of variants in Mendelian Alzheimer's disease genes within the Alzheimer's Disease Sequencing Project.
Dongyu Wang, Alexandra Scalici, Yanbing Wang, Honghuang Lin, Achilleas Pitsillides, Joshua C Bis

J Alzheimers Dis· April 2025

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Clinical and Imaging Markers of Cardiac Function and Brain Health: A Meta-Analysis of Community-Based Studies.
Amber Yaqub, Joshua C Bis, Stefan Frenzel, Marisa Koini, Djass Mbangdadji

Neurology· April 2025

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Methylome-wide association analyses of lipids and modifying effects of behavioral factors in diverse race and ethnicity participants.
Yao Hu, Jeff Haessler, Jessica I Lundin, Burcu F Darst, Eric A Whitsel, Joshua C Bis

Clin Epigenetics· April 2025

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Selected social and lifestyle correlates of brain health markers: the Cross-Cohort Collaboration Consortium.
Leslie Grasset, Joshua C Bis, Stefan Frenzel, Daniel Kojis, Jeannette Simino

Alzheimers Dement· April 2025

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Whole genome sequencing analysis of body mass index identifies novel African ancestry-specific risk allele.
Xinruo Zhang, Jennifer A Brody, Mariaelisa Graff, Heather M Highland, Nathalie Chami, Joshua C Bis

Nat Commun· April 2025

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Genome-wide association study and multi-ancestry meta-analysis identify common variants associated with carotid artery intima-media thickness.
Devendra Meena, Jian Huang, Marjan Zare, Natalie R Hasbani, Boua Palwendé Romuald, Joshua C Bis

medRxiv· April 2025

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Sequencing in over 50,000 cases identifies coding and structural variation underlying atrial fibrillation risk.
Seung Hoan Choi, Sean J Jurgens, Ling Xiao, Matthew C Hill, Christopher M Haggerty, Joshua C Bis

Nat Genet· March 2025

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Rare damaging CCR2 variants are associated with lower lifetime cardiovascular risk.
Marios K Georgakis, Rainer Malik, Omar El Bounkari, Natalie R Hasbani, Jiang Li, Joshua C Bis

Genome Med· March 2025

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Genomic and phenotypic correlates of mosaic loss of chromosome Y in blood.
Yasminka A Jakubek, Xiaolong Ma, Adrienne M Stilp, Fulong Yu, Jason Bacon, Joshua C Bis

Am J Hum Genet· February 2025

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A statistical framework for multi-trait rare variant analysis in large-scale whole-genome sequencing studies.
Xihao Li, Han Chen, Margaret Sunitha Selvaraj, Eric Van Buren, Hufeng Zhou, Joshua C Bis

Nat Comput Sci· February 2025

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Unveiling the Genetic Landscape of Coronary Artery Disease Through Common and Rare Structural Variants.
Kruthika R Iyer, Shoa L Clarke, Rodrigo Guarischi-Sousa, Ketrin Gjoni, Adam S Heath, Joshua C Bis

J Am Heart Assoc· February 2025

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A Large-Scale Genome-wide Association Study of Blood Pressure Accounting for Gene-Depressive Symptomatology Interactions in 564,680 Individuals from Diverse Populations.
Songmi Lee, Clint L Miller, Amy R Bentley, Michael R Brown, Pavithra Nagarajan, Joshua C Bis

Res Sq· February 2025

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The expected polygenic risk score (ePRS) framework: an equitable metric for quantifying polygenetic risk via modeling of ancestral makeup.
Yu-Jyun Huang, Nuzulul Kurniansyah, Matthew O Goodman, Brian W Spitzer, Jiongming Wang, Joshua C Bis

medRxiv· December 2024

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