Publications by authors named "Julie Zhou"

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In vivo base editing rescues ADPKD in a humanized mouse model.
Alice Shasha Cheng, Linda Xiaoyan Li, Julie Xia Zhou, Peter C Harris, James P Calvet

Nat Commun· December 2025

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Aldehyde dehydrogenase 1 A1 regulates the transcription of PD-L1 and its targeting with disulfiram together with PD-L1 immunotherapy synergistically delays cyst growth in ADPKD.
Alice Shasha Cheng, Linda Xiaoyan Li, Julie Xia Zhou, Peter C Harris, James P Calvet

Kidney Int· December 2025

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Cellular senescence and its association with aldose reductase promote cyst growth in autosomal dominant polycystic kidney disease.
Xinyue Mao, Lu Li, Geoffray Lee, Ewud Agborbesong, Julie Xia Zhou

Kidney Int· November 2025

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Ablation of CD22 induces a pro-inflammatory transcriptome shift and endocytic deficits in M2-like macrophages.
Emily N Kukan, Gabrielle L Fabiano, Julie Y Zhou, Ava R Richard, Kevin A Telfer

Glycobiology· November 2025

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GLP-1RA Semaglutide Delays the Progression of ADPKD Through Regulation of Glycolysis, Mitochondria Function and Ketosis.
Jiao Wu, Alice Shasha Cheng, Thomas Weimbs, Peter C Harris, Julie Xia Zhou

FASEB J· August 2025

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M2-Like Macrophages Exhibit Sialic Acid-Enhanced Efferocytosis via the Siglec CD22.
Emily N Kukan, Gabrielle L Fabiano, Leandre M Glendenning, Julie Y Zhou, Kevin A Telfer

FASEB J· July 2025

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Droplet vs Picowell: Considerations for Single-cell Transcriptomic Profiling of Human Colon Biopsies.
Jonathan M Downie, Ryan J Musich, Connor M Geraghty, Alexander Caraballo, Shijie He, Julie Y Zhou

Cell Mol Gastroenterol Hepatol· April 2025

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Novel coenzyme Q6 genetic variant increases susceptibility to pneumococcal disease.
Emma C Walker, Sarah Javati, Elizabeth M Todd, John-Paul Matlam, Xue Lin, Julie Y Zhou

Nat Immunol· December 2024

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Intestinal stem cells enhance local mucosal immunity through apoptotic body phagocytosis.
Julie Y Zhou, Qiuhe Lu, Yujia Hu, Satoru Fujii, Scott T Espenschied

bioRxiv· November 2024

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A host-adapted auxotrophic gut symbiont induces mucosal immunodeficiency.
Qiuhe Lu, Thomas C A Hitch, Julie Y Zhou, Mohammed Dwidar, Naseer Sangwan

Science· September 2024

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DNA methyltransferase 1 (DNMT1) promotes cyst growth and epigenetic age acceleration in autosomal dominant polycystic kidney disease.
Julie Xia Zhou, Linda Xiaoyan Li, Hongbing Zhang, Ewud Agborbesong, Peter C Harris

Kidney Int· August 2024

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TRPV4 Regulates the Macrophage Metabolic Response to Limit Sepsis-induced Lung Injury.
Erica M Orsini, Sanjoy Roychowdhury, Mahesha Gangadhariah, Emily Cross, Susamma Abraham, Julie Y Zhou

Am J Respir Cell Mol Biol· June 2024

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Optimizing single-cell RNA sequencing methods for human colon biopsies: droplet-based vs. picowell-based platforms.
Jonathan M Downie, Ryan J Musich, Connor M Geraghty, Alexander Caraballo, Shijie He, Julie Y Zhou

bioRxiv· June 2024

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A T17-intrinsic IL-1β-STAT5 axis drives steroid resistance in autoimmune neuroinflammation.
William A Miller-Little, Xing Chen, Vanessa Salazar, Caini Liu, Katarzyna Bulek, Julie Y Zhou

Sci Immunol· May 2024

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SMYD3 Controls Ciliogenesis by Regulating Distinct Centrosomal Proteins and Intraflagellar Transport Trafficking.
Ewud Agborbesong, Julie Xia Zhou, Hongbing Zhang, Linda Xiaoyan Li, Peter C Harris

Int J Mol Sci· May 2024

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CD74 Promotes Cyst Growth and Renal Fibrosis in Autosomal Dominant Polycystic Kidney Disease.
Julie Xia Zhou, Alice Shasha Cheng, Li Chen, Linda Xiaoyan Li, Ewud Agborbesong

Cells· March 2024

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Overexpression of SMYD3 Promotes Autosomal Dominant Polycystic Kidney Disease by Mediating Cell Proliferation and Genome Instability.
Ewud Agborbesong, Julie Xia Zhou, Hongbing Zhang, Linda Xiaoyan Li, Peter C Harris

Biomedicines· March 2024

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Platelet-localized ST6Gal1 does not impact IgG sialylation.
Leandre M Glendenning, Julie Y Zhou, Emily N Kukan, Chao Gao, Richard D Cummings

Glycobiology· December 2023

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Phosphorylation of MIF by PIP4K2a is necessary for cilia biogenesis.
Lu Zhang, Hongbing Zhang, Ewud Agborbesong, Julie Xia Zhou, Xiaogang Li

Cell Death Dis· December 2023

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Select symbionts drive high IgA levels in the mouse intestine.
Shanshan Zhang, Yi Han, Whitman Schofield, Michael Nicosia, Paul E Karell, Julie Y Zhou

Cell Host Microbe· October 2023

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Intestinal Tr1 Cells Confer Protection against Colitis in the Absence of Foxp3+ Regulatory T Cell-Derived IL-10.
Julie Y Zhou, Leandre M Glendenning, Jill M Cavanaugh, Sarah K McNeer, Wendy A Goodman

Immunohorizons· June 2023

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Drug repurposing in autosomal dominant polycystic kidney disease.
Julie Xia Zhou, Vicente E Torres

Kidney Int· May 2023

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Autosomal Dominant Polycystic Kidney Disease Therapies on the Horizon.
Julie Xia Zhou, Vicente E Torres

Adv Kidney Dis Health· May 2023

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Bromodomain Protein BRD4-Mediated Mutant p53 Transcription Promotes TNBC Progression.
Julie Xia Zhou, Ewud Agborbesong, Linda Xiaoyan Li, Xiaogang Li

Int J Mol Sci· December 2022

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Single-Cell and CellChat Resolution Identifies Collecting Duct Cell Subsets and Their Communications with Adjacent Cells in PKD Kidneys.
Linda Xiaoyan Li, Xu Zhang, Hongbing Zhang, Ewud Agborbesong, Julie Xia Zhou

Cells· December 2022

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