Publications by authors named "Jun Lin Guan"

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Endothelial Transcription Factor EB Protects Against Doxorubicin-Induced Endothelial Toxicity and Cardiac Dysfunction.
Wa Du, Madison Ringer, Wei Huang, Darshini Desai, Golam Iftakhar Khandakar, Jun-Lin Guan

Circulation· December 2025

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Novel Metastasis Suppressor PI3KC2β Is Mediated by mTORC1 Signaling in Breast Cancer.
Kanakaraju Manupati, Mingang Hao, Suhua Li, Sushma Maharjan, Jun-Lin Guan

Mol Cancer Res· September 2025

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Protocol for in vivo CRISPR knockout screening of autophagy genes to identify breast cancer metastasis suppressors.
Mingang Hao, Peixin Lu, Jun-Lin Guan

STAR Protoc· June 2025

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Site-specific photo-crosslinking of Hsc70 with the KFERQ pentapeptide motif in a chaperone-mediated autophagy and microautophagy substrate in mammalian cells.
Tatsuro Seike, Kazue Terasawa, Takanori Iwata, Jun-Lin Guan, Tetsuro Watabe

Biochem Biophys Res Commun· December 2024

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VAMP2 controls murine epidermal differentiation and carcinogenesis by regulation of nucleophagy.
Han Liu, Peihong Su, Yuanyuan Li, Alex Hoover, Sophie Hu, Jun-Lin Guan

Dev Cell· August 2024

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Individual Atg8 paralogs and a bacterial metabolite sequentially promote hierarchical CASM-xenophagy induction and transition.
Chisato Sakuma, Sayaka Shizukuishi, Michinaga Ogawa, Yuko Honjo, Haruko Takeyama, Jun-Lin Guan

Cell Rep· May 2024

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Autophagy-dependent expression of osteopontin and its downstream Stat3 signaling contributes to lymphatic malformation progression to lymphangiosarcoma.
Fuchun Yang, Jun-Lin Guan

Autophagy· April 2024

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Retraction Note: Molecular characterization of LC3-associated phagocytosis reveals distinct roles for Rubicon, NOX2 and autophagy proteins.
Jennifer Martinez, R K Subbarao Malireddi, Qun Lu, Larissa Dias Cunha, Stephane Pelletier, Jun-Lin Guan

Nat Cell Biol· April 2024

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Role of NuMA1 in breast cancer stem cells with implications for combination therapy of PIM1 and autophagy inhibition in triple negative breast cancer.
Kanakaraju Manupati, Mingang Hao, Michael Haas, Syn Kok Yeo, Jun-Lin Guan

Res Sq· April 2024

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AZI2 mediates TBK1 activation at unresolved selective autophagy cargo receptor complexes with implications for CD8 T-cell infiltration in breast cancer.
Syn Kok Yeo, Michael Haas, Kanakaraju Manupati, Mingang Hao, Fuchun Yang, Jun-Lin Guan

Autophagy· March 2024

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In vivo CRISPR knockout screen identifies p47 as a suppressor of HER2+ breast cancer metastasis by regulating NEMO trafficking and autophagy flux.
Mingang Hao, Peixin Lu, Sarah Sotropa, Kanakaraju Manupati, Syn Kok Yeo, Jun-Lin Guan

Cell Rep· February 2024

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Mitochondrial nucleoid condensates drive peripheral fission through high membrane curvature.
Qixin Chen, Liu-Yi Liu, Zhiqi Tian, Zhou Fang, Kang-Nan Wang, Jun-Lin Guan

Cell Rep· December 2023

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Advanced imaging techniques for tracking drug dynamics at the subcellular level.
Chengying Zhang, Zhiqi Tian, Rui Chen, Fiona Rowan, Kangqiang Qiu, Jun-Lin Guan

Adv Drug Deliv Rev· August 2023

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Regulation of RB1CC1/FIP200 stability and autophagy function by CREBBP-mediated acetylation in an intrinsically disordered region.
Fei Yi, Chunmiao Cai, Banzhan Ruan, Mingang Hao, Syn Kok Yeo, Jun-Lin Guan

Autophagy· June 2023

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FAK-MAPK-dependent adhesion disassembly downstream of L1 contributes to semaphorin3A-induced collapse.
Ahmad Bechara, Homaira Nawabi, Frédéric Moret, Avraham Yaron, Eli Weaver, Jun-Lin Guan

EMBO J· May 2023

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Autophagy inhibition prevents lymphatic malformation progression to lymphangiosarcoma by decreasing osteopontin and Stat3 signaling.
Fuchun Yang, Shiva Kalantari, Banzhan Ruan, Shaogang Sun, Zhaoqun Bian, Jun-Lin Guan

Nat Commun· February 2023

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An ER-targeted "reserve-release" fluorogen for topological quantification of reticulophagy.
Hongbao Fang, Lianting Hu, Qixin Chen, Shanshan Geng, Kangqiang Qiu, Jun-Lin Guan

Biomaterials· January 2023

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TRIM27 cooperates with STK38L to inhibit ULK1-mediated autophagy and promote tumorigenesis.
Yi Yang, Yifu Zhu, Shuai Zhou, Peipei Tang, Ran Xu, Jun-Lin Guan

EMBO J· July 2022

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Light-activated mitochondrial fission through optogenetic control of mitochondria-lysosome contacts.
Kangqiang Qiu, Weiwei Zou, Hongbao Fang, Mingang Hao, Kritika Mehta, Jun-Lin Guan

Nat Commun· July 2022

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Targeting Autophagy in Thyroid Cancer: EMT, Apoptosis, and Cancer Stem Cells.
Tammy M Holm, Syn Yeo, Kevin M Turner, Jun-Lin Guan

Front Cell Dev Biol· June 2022

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Autophagy in PDGFRα+ mesenchymal cells is essential for intestinal stem cell survival.
Yang Yang, Maria Gomez, Timothy Marsh, Laura Poillet-Perez, Akshada Sawant, Jun-Lin Guan

Proc Natl Acad Sci U S A· May 2022

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Supercritical fluid chromatography-mass spectrometry enables simultaneous measurement of all phosphoinositide regioisomers.
Yuta Shimanaka, Keiko Matsumoto, Yuki Tanaka, Yuki Ishino, Shenwei Ni, Jun-Lin Guan

Commun Chem· May 2022

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Biglycan Promotes Cancer Stem Cell Properties, NFκB Signaling and Metastatic Potential in Breast Cancer Cells.
Kanakaraju Manupati, Ritama Paul, Mingang Hao, Michael Haas, Zhaoqun Christine Bian, Jun-Lin Guan

Cancers (Basel)· January 2022

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Non-canonical function of FIP200 is required for neural stem cell maintenance and differentiation by limiting TBK1 activation and p62 aggregate formation.
Hang Liu, Chenran Wang, Fei Yi, Syn Yeo, Michael Haas, Jun-Lin Guan

Sci Rep· December 2021

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Publisher Correction: Autophagy promotes growth of tumors with high mutational burden by inhibiting a T-cell immune response.
Laura Poillet-Perez, Daniel W Sharp, Yang Yang, Saurabh V Laddha, Maria Ibrahim, Jun-Lin Guan

Nat Cancer· September 2021

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