Publications by authors named "KG Helmer"

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MarkVCID2 Consortium for Clinical Validation of Biomarkers of Cerebral Small Vessel Disease: Validation Framework and Baseline Characteristics.
Steven M Greenberg, Marylin S Albert, Hongyu An, Konstantinos Arfanakis, Arnold M Evia, Karl G Helmer

Ann Neurol· September 2025

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Technical and clinical validation of a novel deep learning-based white matter hyperintensity segmentation tool.
Benno Gesierich, Lukas Pirpamer, Dominik S Meier, Michael Amann, Minne N Cerfontaine, Karl G Helmer

Cereb Circ Cogn Behav· September 2025

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Safety and efficacy of leriglitazone in childhood cerebral adrenoleukodystrophy (NEXUS): an interim analysis of an open-label, phase 2/3 trial.
Ángeles García-Cazorla, Caroline Sevin, Juliana Ribeiro Constante, Elise Yazbeck, Hendrik Rosewich, Karl G Helmer

EClinicalMedicine· June 2025

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MRI free water mediates the association between diffusion tensor image analysis along the perivascular space and executive function in four independent middle to aged cohorts.
Xiaodan Liu, Pauline Maillard, Giuseppe Barisano, Arvind Caprihan, Steven Cen, Karl G Helmer

Alzheimers Dement· February 2025

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Extended Technical and Clinical Validation of Deep Learning-Based Brainstem Segmentation for Application in Neurodegenerative Diseases.
Benno Gesierich, Laura Sander, Lukas Pirpamer, Dominik S Meier, Esther Ruberte, Karl G Helmer

Hum Brain Mapp· February 2025

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Biological validation of peak-width of skeletonized mean diffusivity as a VCID biomarker: The MarkVCID Consortium.
Alison M Luckey, Saptaparni Ghosh, Chen-Pin Wang, Alexa Beiser, Rebecca Bernal, Karl G Helmer

Alzheimers Dement· December 2024

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Cross-Vendor Test-Retest Validation of Diffusion Tensor Image Analysis along the Perivascular Space (DTI-ALPS) for Evaluating Glymphatic System Function.
Xiaodan Liu, Giuseppe Barisano, Xingfeng Shao, Kay Jann, John M Ringman, Karl G Helmer

Aging Dis· August 2024

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Cerebrovascular reactivity MRI as a biomarker for cerebral small vessel disease-related cognitive decline: Multi-site validation in the MarkVCID Consortium.
Peiying Liu, Zixuan Lin, Kaisha Hazel, George Pottanat, Cuimei Xu, Karl G Helmer

Alzheimers Dement· August 2024

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Transformer-based deep learning denoising of single and multi-delay 3D arterial spin labeling.
Qinyang Shou, Chenyang Zhao, Xingfeng Shao, Kay Jann, Hosung Kim, Karl G Helmer

Magn Reson Med· February 2024

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Birth of the Topological Atlas and Repository for Acupoint Research.
Vitaly Napadow, Richard E Harris, Karl G Helmer

J Integr Complement Med· December 2023

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Multi-Site Cross-Site Inter-Rater and Test-Retest Reliability and Construct Validity of the MarkVCID White Matter Hyperintensity Growth and Regression Protocol.
Ahmed A Bahrani, Erin L Abner, Charles S DeCarli, Justin M Barber, Abigail C Sutton, Karl G Helmer

J Alzheimers Dis· November 2023

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Neuroimaging standards for research into small vessel disease-advances since 2013.
Marco Duering, Geert Jan Biessels, Amy Brodtmann, Christopher Chen, Charlotte Cordonnier, Karl G Helmer

Lancet Neurol· July 2023

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NIDM-Terms: community-based terminology management for improved neuroimaging dataset descriptions and query.
Nazek Queder, Vivian B Tien, Sanu Ann Abraham, Sebastian Georg Wenzel Urchs, Karl G Helmer

Front Neuroinform· July 2023

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Transformer based deep learning denoising of single and multi-delay 3D Arterial Spin Labeling.
Qinyang Shou, Chenyang Zhao, Xingfeng Shao, Kay Jann, Karl G Helmer

medRxiv· April 2023

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MRI free water as a biomarker for cognitive performance: Validation in the MarkVCID consortium.
Pauline Maillard, Laura J Hillmer, Hanzhang Lu, Konstantinos Arfanakis, Brian T Gold, Karl G Helmer

Alzheimers Dement (Amst)· December 2022

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The Neuroimaging Data Model Linear Regression Tool (nidm_linreg): PyNIDM Project.
Ashmita Kumar, Albert Crowley, Nazek Queder, J B Poline, Satrajit S Ghosh, Karl G Helmer

F1000Res· July 2022

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Instrumental validation of free water, peak-width of skeletonized mean diffusivity, and white matter hyperintensities: MarkVCID neuroimaging kits.
Pauline Maillard, Hanzhang Lu, Konstantinos Arfanakis, Brian T Gold, Christopher E Bauer, Karl G Helmer

Alzheimers Dement (Amst)· March 2022

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Multi-vendor and multisite evaluation of cerebrovascular reactivity mapping using hypercapnia challenge.
Peiying Liu, Dengrong Jiang, Marilyn Albert, Christopher E Bauer, Arvind Caprihan, Karl G Helmer

Neuroimage· December 2021

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MarkVCID cerebral small vessel consortium: II. Neuroimaging protocols.
Hanzhang Lu, Amir H Kashani, Konstantinos Arfanakis, Arvind Caprihan, Charles DeCarli, Karl G Helmer

Alzheimers Dement· April 2021

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MarkVCID cerebral small vessel consortium: I. Enrollment, clinical, fluid protocols.
Donna Wilcock, Gregory Jicha, Deborah Blacker, Marilyn S Albert, Lina M D'Orazio, Karl G Helmer

Alzheimers Dement· April 2021

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Characterization of Diffusion Metric Map Similarity in Data From a Clinical Data Repository Using Histogram Distances.
Graham C Warner, Karl G Helmer

Front Neurosci· March 2018

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Sharing brain mapping statistical results with the neuroimaging data model.
Camille Maumet, Tibor Auer, Alexander Bowring, Gang Chen, Samir Das, Karl G Helmer

Sci Data· December 2016

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QIN DAWG Validation of Gradient Nonlinearity Bias Correction Workflow for Quantitative Diffusion-Weighted Imaging in Multicenter Trials.
Dariya I Malyarenko, Lisa J Wilmes, Lori R Arlinghaus, Michael A Jacobs, Wei Huang, Karl G Helmer

Tomography· December 2016

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Multi-site study of diffusion metric variability: effects of site, vendor, field strength, and echo time on regions-of-interest and histogram-bin analyses.
K G Helmer, M-C Chou, R I Preciado, B Gimi, N K Rollins

Proc SPIE Int Soc Opt Eng· February 2016

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Multi-site Study of Diffusion Metric Variability: Characterizing the Effects of Site, Vendor, Field Strength, and Echo Time using the Histogram Distance.
K G Helmer, M-C Chou, R I Preciado, B Gimi, N K Rollins

Proc SPIE Int Soc Opt Eng· February 2016

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