Publications by authors named "Kailin Yu"

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Glymphatic system: a self-purification circulation in brain.
Siying Chen, Huijing Wang, Lini Zhang, Yingying Xi, Yiying Lu, Kailin Yu, Yujie Zhu, Izmailova Regina, Yong Bi, Fang Tong

Front Cell Neurosci· February 2025

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Ultrasonography diagnosis of dumbbell-shaped C5 cervical schwannoma: a case report and literature review.
Kailin Yu, Jingsen Chen, Minqiang Pan, Kanlun Xu, Pintong Huang, Yucong Peng

Front Oncol· June 2025

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LC-MS/MS for Assessing the Incorporation and Repair of -Alkyl-2'-deoxyguanosine in Genomic DNA.
Su Guo, Lin Li, Kailin Yu, Ying Tan, Yinsheng Wang

Chem Res Toxicol· October 2022

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Targeted Quantitative Profiling of Epitranscriptomic Reader, Writer, and Eraser Proteins Using Stable Isotope-Labeled Peptides.
Tianyu F Qi, Xiaochuan Liu, Feng Tang, Jiekai Yin, Kailin Yu

Anal Chem· September 2022

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Quantitative proteomics revealed new functions of ALKBH4.
Kailin Yu, Tianyu F Qi, Weili Miao, Xiaochuan Liu, Yinsheng Wang

Proteomics· April 2022

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Nintedanib overcomes drug resistance from upregulation of FGFR signalling and imatinib-induced KIT mutations in gastrointestinal stromal tumours.
Juan Liu, Jingjing Gao, Aoli Wang, Zongru Jiang, Shuang Qi, Kailin Yu

Mol Oncol· April 2022

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Modulation of N-terminal methyltransferase 1 by an N-methyladenosine-based epitranscriptomic mechanism.
David Bade, Qian Cai, Lin Li, Kailin Yu, Xiaoxia Dai

Biochem Biophys Res Commun· March 2021

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Selectively targeting FLT3-ITD mutants over FLT3-wt by a novel inhibitor for acute myeloid leukemia.
Aoli Wang, Chen Hu, Cheng Chen, Xiaofei Liang, Beilei Wang, Kailin Yu

Haematologica· February 2021

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Outcomes of a modified Bresler procedure for the treatment of rectocele with rectal intussusception.
Qun Deng, Kai-Lin Yu, Zhi-Yong Liu, Zhong Shen, Ya-Hui Wang

Gastroenterol Rep (Oxf)· December 2020

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Discovery of a novel and highly selective CDK9 kinase inhibitor (JSH-009) with potent antitumor efficacy in preclinical acute myeloid leukemia models.
Li Wang, Chen Hu, Aoli Wang, Cheng Chen, Jiaxin Wu, Kailin Yu

Invest New Drugs· October 2020

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Discovery of a highly potent and selective Bruton's tyrosine kinase inhibitor avoiding impairment of ADCC effects for B-cell non-Hodgkin lymphoma.
Juan Liu, Qianmao Liang, Aoli Wang, Fengming Zou, Ziping Qi, Kailin Yu

Signal Transduct Target Ther· September 2020

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Streptococcus bovis Contributes to the Development of Colorectal Cancer via Recruiting CD11b⁺TLR-4⁺ Cells.
Qun Deng, Changjian Wang, Kailin Yu, Yahui Wang, Qinyan Yang

Med Sci Monit· August 2020

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Proteome-wide Interrogation of Small GTPases Regulated by -Methyladenosine Modulators.
Yen-Yu Yang, Kailin Yu, Lin Li, Ming Huang, Yinsheng Wang

Anal Chem· July 2020

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Chemical Proteomic Profiling of the Interacting Proteins of Isoprenoid Pyrophosphates.
Rong Cai, Xuejiao Dong, Kailin Yu, Xiaomei He, Xiaochuan Liu

Anal Chem· June 2020

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All-trans retinoic acid exerts selective anti-FLT3-ITD acute myeloid leukemia efficacy through downregulating Chk1 kinase.
Wenliang Wang, Zongru Jiang, Li Wang, Aoli Wang, Juan Liu, Kailin Yu

Cancer Lett· March 2020

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Discovery of a highly selective VEGFR2 kinase inhibitor CHMFL-VEGFR2-002 as a novel anti-angiogenesis agent.
Zongru Jiang, Li Wang, Xuesong Liu, Cheng Chen, Beilei Wang, Kailin Yu

Acta Pharm Sin B· March 2020

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Discovery of ( E)- N-(3-Fluorophenyl)- N-(3-(2-(pyridin-2-yl)vinyl)-1 H-indazol-6-yl)malonamide (CHMFL-KIT-033) as a Novel c-KIT T670I Mutant Selective Kinase Inhibitor for Gastrointestinal Stromal Tumors (GISTs).
Xuesong Liu, Beilei Wang, Cheng Chen, Ziping Qi, Fengming Zou, Kailin Yu

J Med Chem· May 2019

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Axitinib overcomes multiple imatinib resistant cKIT mutations including the gatekeeper mutation T670I in gastrointestinal stromal tumors.
Feiyang Liu, Fengming Zou, Cheng Chen, Kailin Yu, Xiaochuan Liu, Yujiao Cai

Ther Adv Med Oncol· May 2019

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Discovery of N-(4-(6-Acetamidopyrimidin-4-yloxy)phenyl)-2-(2-(trifluoromethyl)phenyl)acetamide (CHMFL-FLT3-335) as a Potent FMS-like Tyrosine Kinase 3 Internal Tandem Duplication (FLT3-ITD) Mutant Selective Inhibitor for Acute Myeloid Leukemia.
Xiaofei Liang, Beilei Wang, Cheng Chen, Aoli Wang, Chen Hu, Kailin Yu

J Med Chem· January 2019

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Discovery of (S)-2-amino-N-(5-(6-chloro-5-(3-methylphenylsulfonamido)pyridin-3-yl)-4-methylthiazol-2-yl)-3-methylbutanamide (CHMFL-PI3KD-317) as a potent and selective phosphoinositide 3-kinase delta (PI3Kδ) inhibitor.
Xiaofei Liang, Feng Li, Cheng Chen, Zongru Jiang, Aoli Wang, Kailin Yu, Yuxin Wang

Eur J Med Chem· August 2018

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Discovery of a highly selective KIT kinase primary V559D mutant inhibitor for gastrointestinal stromal tumors (GISTs).
Kailin Yu, Xuesong Liu, Zongru Jiang, Chen Hu, Fengming Zou

Oncotarget· December 2017

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Discovery of 1-(4-(4-Amino-3-(4-(2-morpholinoethoxy)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)phenyl)-3-(5-(tert-butyl)isoxazol-3-yl)urea (CHMFL-FLT3-213) as a Highly Potent Type II FLT3 Kinase Inhibitor Capable of Overcoming a Variety of FLT3 Kinase Mutants in FLT3-ITD Positive AML.
Aoli Wang, Xixiang Li, Cheng Chen, Hong Wu, Ziping Qi, Kailin Yu

J Med Chem· October 2017

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Structure-activity relationship investigation for benzonaphthyridinone derivatives as novel potent Bruton's tyrosine kinase (BTK) irreversible inhibitors.
Beilei Wang, Yuanxin Deng, Yongfei Chen, Kailin Yu, Aoli Wang

Eur J Med Chem· September 2017

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The paradigm of tumor shrinkage and rapid liver remnant hypertrophy for conversion of initially unresectable colorectal liver metastasis: a case report and literature review.
Nan Xiao, Kailin Yu, Shaojun Yu, Jianjun Wu, Jian Wang

World J Surg Oncol· August 2017

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Discovery and characterization of a novel irreversible EGFR mutants selective and potent kinase inhibitor CHMFL-EGFR-26 with a distinct binding mode.
Chen Hu, Aoli Wang, Hong Wu, Ziping Qi, Xixiang Li, Kailin Yu, Cai-Hong Yun

Oncotarget· March 2017

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