Publications by authors named "Kate D Sutherland"

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Inhibition of the minor spliceosome restricts the growth of a broad spectrum of cancers.
Karen Doggett, Kimberly J Morgan, Anouk M Olthof, Stephen Mieruszynski, Benjamin B Williams, Alexandra L Garnham, Michael J G Milevskiy, Lachlan Whitehead, Janine Coates, Michael Buchert

August 2025

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A glycoprotein VI signaling defect in newly formed platelets generated in stress thrombopoiesis.
Stephanie R Hyslop, Jason Corbin, Pradnya Gangatirkar, Marion Lebois, Amanda E Au, Kate D Sutherland

J Thromb Haemost· June 2025

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SMARCA4 is essential for early-stage tumor development but its loss promotes late-stage cancer progression in small-cell lung cancer.
Nicole A Kirk, Jin Ng, Kate-Lin Ly, Young Ho Ban, Godfrey Dzhivhuho, Kate D Sutherland

bioRxiv· May 2025

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Breathing new insights into the role of mutant p53 in lung cancer.
Tianwei Chen, Lauren M Ashwood, Olga Kondrashova, Andreas Strasser, Gemma Kelly, Kate D Sutherland

Oncogene· February 2025

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Molecular and Pathologic Characterization of YAP1-Expressing Small Cell Lung Cancer Cell Lines Leads to Reclassification as SMARCA4-Deficient Malignancies.
Jin Ng, Ling Cai, Luc Girard, Owen W J Prall, Neeha Rajan, Kate D Sutherland

Clin Cancer Res· May 2024

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A Multiplexed Approach to Assess Small Cell Lung Cancer Subtype Heterogeneity in Primary and Patient-Derived Tumor Samples.
Jin Ng, Emma Pan, Alex Johnston, Nina Tubau Ribera, Ariena Kersbergen, Kate D Sutherland

Methods Mol Biol· April 2024

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Next batter up! Targeting cancers with KRAS-G12D mutations.
Mara N Zeissig, Lauren M Ashwood, Olga Kondrashova, Kate D Sutherland

Trends Cancer· November 2023

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On Target: An Intrapulmonary Transplantation Method for Modelling Lung Tumor Development in its Native Microenvironment.
Jackson A McDonald, Leanne Scott, Jessica Van Zuylekom, Steven Holloway, Benjamin J Blyth, Kate D Sutherland

Methods Mol Biol· June 2023

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Early immune pressure initiated by tissue-resident memory T cells sculpts tumor evolution in non-small cell lung cancer.
Clare E Weeden, Velimir Gayevskiy, Claire Marceaux, Daniel Batey, Tania Tan, Kate D Sutherland

Cancer Cell· May 2023

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Design and characterization of a heterobifunctional degrader of KEAP1.
Hao Chen, Nghi H Nguyen, Charlene M Magtoto, Simon A Cobbold, Grace M Bidgood, Kate D Sutherland

Redox Biol· February 2023

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Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes.
Christina E Sparbier, Andrea Gillespie, Juliana Gomez, Nishi Kumari, Ali Motazedian, Kate D Sutherland

Nat Cell Biol· February 2023

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Inhibition of LSD1 with Bomedemstat Sensitizes Small Cell Lung Cancer to Immune Checkpoint Blockade and T-Cell Killing.
Joseph B Hiatt, Holly Sandborg, Sarah M Garrison, Henry U Arnold, Sheng-You Liao, Kate D Sutherland

Clin Cancer Res· October 2022

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Glutaminase inhibition impairs CD8 T cell activation in STK11-/Lkb1-deficient lung cancer.
Sarah A Best, Patrick M Gubser, Shalini Sethumadhavan, Ariena Kersbergen, Yashira L Negrón Abril, Kate D Sutherland

Cell Metab· June 2022

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Killing SCLC: insights into how to target a shapeshifting tumor.
Kate D Sutherland, Abbie S Ireland, Trudy G Oliver

Genes Dev· March 2022

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Absence of pro-survival A1 has no impact on inflammatory cell survival in vivo during acute lung inflammation and peritonitis.
Lahiru Gangoda, Robyn L Schenk, Sarah A Best, Christina Nedeva, Cynthia Louis, Kate D Sutherland

Cell Death Differ· January 2022

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Delineating the roles of Grhl2 in craniofacial development through tissue-specific conditional deletion and epistasis approaches in mouse.
Michael de Vries, Harley G Owens, Marina R Carpinelli, Darren Partridge, Ariena Kersbergen, Kate D Sutherland

Dev Dyn· August 2021

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An Integrated Molecular Grafting Approach for the Design of Keap1-Targeted Peptide Inhibitors.
Huawu Yin, Yen-Hua Huang, Sarah A Best, Kate D Sutherland, David J Craik

ACS Chem Biol· July 2021

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Exploring natural killer cell immunology as a therapeutic strategy in lung cancer.
Jonas B Hess, Kate D Sutherland, Sarah A Best

Transl Lung Cancer Res· June 2021

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Critical cancer vulnerabilities identified by unbiased CRISPR/Cas9 screens inform on efficient cancer Immunotherapy.
Margaret A Potts, Jackson A McDonald, Kate D Sutherland, Marco J Herold

Eur J Immunol· December 2020

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Consequences of Zmat3 loss in c-MYC- and mutant KRAS-driven tumorigenesis.
Sarah A Best, Cassandra J Vandenberg, Etna Abad, Lachlan Whitehead, Laia Guiu, Kate D Sutherland

Cell Death Dis· October 2020

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Harnessing Natural Killer Immunity in Metastatic SCLC.
Sarah A Best, Jonas B Hess, Fernando Souza-Fonseca-Guimaraes, Joseph Cursons, Ariena Kersbergen, Kate D Sutherland

J Thorac Oncol· September 2020

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Targeting platelets for improved outcome in KRAS-driven lung adenocarcinoma.
Stephanie R Hyslop, Marliese Alexander, Alesha A Thai, Ariena Kersbergen, Andrew J Kueh, Kate D Sutherland

Oncogene· July 2020

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Balancing the Count: Harmonizing Panel-Based Tumor Mutational Burden Assessment.
Kate D Sutherland, Joseph H A Vissers

J Thorac Oncol· July 2020

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NOTCH Your Usual Suspect: MYC Charged with Controlling Neuroendocrine Cell-Fate in Small Cell Lung Cancer.
Jin Ng, Kate D Sutherland

Cancer Cell· July 2020

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New Approaches to SCLC Therapy: From the Laboratory to the Clinic.
John T Poirier, Julie George, Taofeek K Owonikoko, Anton Berns, Elisabeth Brambilla, Kate D Sutherland

J Thorac Oncol· April 2020

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