Publications by authors named "Kaycie Deyle"

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Macrocycle synthesis strategy based on step-wise "adding and reacting" three components enables screening of large combinatorial libraries.
Ganesh K Mothukuri, Sangram S Kale, Carl L Stenbratt, Alessandro Zorzi, Jonathan Vesin, Julien Bortoli Chapalay, Kaycie Deyle, Gerardo Turcatti, Laura Cendron, Alessandro Angelini

June 2020

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Cyclic peptide FXII inhibitor provides safe anticoagulation in a thrombosis model and in artificial lungs.
Jonas Wilbs, Xu-Dong Kong, Simon J Middendorp, Raja Prince, Alida Cooke, Kaycie Deyle

Nat Commun· August 2020

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De novo development of proteolytically resistant therapeutic peptides for oral administration.
Xu-Dong Kong, Jun Moriya, Vanessa Carle, Florence Pojer, Luciano A Abriata, Kaycie Deyle

Nat Biomed Eng· May 2020

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Engineered Peptide Macrocycles Can Inhibit Matrix Metalloproteinases with High Selectivity.
Khan Maola, Jonas Wilbs, Jeremy Touati, Michal Sabisz, Xu-Dong Kong, Kaycie Deyle

Angew Chem Int Ed Engl· August 2019

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Cyclization of peptides with two chemical bridges affords large scaffold diversities.
Sangram S Kale, Camille Villequey, Xu-Dong Kong, Alessandro Zorzi, Kaycie Deyle

Nat Chem· July 2018

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Drugs Based on de -developed Peptides are Coming of Age mune is a.
Kaycie Deyle, Christian Heinis

Chimia (Aarau)· June 2018

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Correction to A Chemically Synthesized Capture Agent Enables the Selective, Sensitive, and Robust Electrochemical Detection of Anthrax Protective Antigen.
Blake Farrow, Sung A Hong, Errika C Romero, Bert Lai, Matthew B Coppock, Kaycie M Deyle

ACS Nano· May 2018

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Corrigendum: Epitope Targeting of Tertiary Protein Structure Enables Target-Guided Synthesis of a Potent In-Cell Inhibitor of Botulinum Neurotoxin.
Blake Farrow, Michelle Wong, Jacquie Malette, Bert Lai, Kaycie M Deyle

Angew Chem Int Ed Engl· February 2018

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Phage Selection of Cyclic Peptides for Application in Research and Drug Development.
Kaycie Deyle, Xu-Dong Kong, Christian Heinis

Acc Chem Res· August 2017

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Acylated heptapeptide binds albumin with high affinity and application as tag furnishes long-acting peptides.
Alessandro Zorzi, Simon J Middendorp, Jonas Wilbs, Kaycie Deyle, Christian Heinis

Nat Commun· July 2017

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Cyclic peptide therapeutics: past, present and future.
Alessandro Zorzi, Kaycie Deyle, Christian Heinis

Curr Opin Chem Biol· June 2017

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A General Synthetic Approach for Designing Epitope Targeted Macrocyclic Peptide Ligands.
Samir Das, Arundhati Nag, JingXin Liang, David N Bunck, Aiko Umeda, Kaycie M Deyle

Angew Chem Int Ed Engl· November 2015

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Epitope targeting of tertiary protein structure enables target-guided synthesis of a potent in-cell inhibitor of botulinum neurotoxin.
Blake Farrow, Michelle Wong, Jacquie Malette, Bert Lai, Kaycie M Deyle

Angew Chem Int Ed Engl· June 2015

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A protein-targeting strategy used to develop a selective inhibitor of the E17K point mutation in the PH domain of Akt1.
Kaycie M Deyle, Blake Farrow, Ying Qiao Hee, Jeremy Work, Michelle Wong

Nat Chem· May 2015

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A cocktail of thermally stable, chemically synthesized capture agents for the efficient detection of anti-gp41 antibodies from human sera.
Jessica A Pfeilsticker, Aiko Umeda, Blake Farrow, Connie L Hsueh, Kaycie M Deyle

PLoS One· August 2014

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A chemical epitope-targeting strategy for protein capture agents: the serine 474 epitope of the kinase Akt2.
Arundhati Nag, Samir Das, Mary Beth Yu, Kaycie M Deyle, Steven W Millward

Angew Chem Int Ed Engl· December 2013

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A chemically synthesized capture agent enables the selective, sensitive, and robust electrochemical detection of anthrax protective antigen.
Blake Farrow, Sung A Hong, Errika C Romero, Bert Lai, Matthew B Coppock, Kaycie M Deyle

ACS Nano· October 2013

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Iterative in situ click chemistry assembles a branched capture agent and allosteric inhibitor for Akt1.
Steven W Millward, Ryan K Henning, Gabriel A Kwong, Suresh Pitram, Heather D Agnew, Kaycie M Deyle

J Am Chem Soc· November 2011

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