Publications by authors named "Kelly Hawley"

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Dual Treponemal and Non-Treponemal Rapid Test for Syphilis in People Living with HIV: A Diagnostic Accuracy Study.
Jose Fernando Fuertes-Bucheli, Sebastian A Silva-Peña, Luisa Hurtado-Rossi, Carol Ospina-Cortes, Lady G Ramírez, Kelly L Hawley

Sex Transm Dis· December 2025

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Analysis of subsp. predicted outer membrane proteins (OMPeomes) in 21 clinical samples: variant sequences are predominantly surface-exposed.
Petra Pospíšilová, Pavla Fedrová, Eliška Vrbová, Christopher M Hennelly, Farhang Aghakhanian, Kelly L Hawley

mSphere· September 2025

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Modeling the Impact of Time to Treatment on Syphilis Prevalence: A Theoretical Mathematical Model of People Living With HIV in Colombia.
Jonny A Garcia-Luna, Norman Maldonado, Kelly L Hawley, Justin D Radolf, Neal Alexander

Sex Transm Dis· August 2025

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Sequence variability of BamA and FadL candidate vaccinogens suggests divergent evolutionary paths of outer membrane proteins.
Everton B Bettin, Farhang Aghakhanian, Christopher M Hennelly, Wentao Chen, Timothy C Davenport, Kelly L Hawley

J Bacteriol· August 2025

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Solubilization of Membrane Proteins using designed protein WRAPS.
Ljubica Mihaljević, David E Kim, Helen E Eisenach, Pooja D Bandawane, Andrew J Borst, Kelly L Hawley

bioRxiv· February 2025

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Development and utilization of expressing green fluorescent protein to study spirochete-host interactions and antibody-mediated clearance: expanding the toolbox for syphilis research.
Kristina N Delgado, Crystal F Vicente, Christopher M Hennelly, Farhang Aghakhanian, Jonathan B Parr, Kelly L Hawley

mBio· January 2025

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Clinical Presentation of Early Syphilis and Genomic Sequences of Treponema pallidum Strains in Patient Specimens and Isolates Obtained by Rabbit Inoculation.
Ligang Yang, Xiaohui Zhang, Wentao Chen, Arlene C Seña, Heping Zheng, Kelly L Hawley

J Infect Dis· December 2024

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Immunodominant extracellular loops of Treponema pallidum FadL outer membrane proteins elicit antibodies with opsonic and growth-inhibitory activities.
Kristina N Delgado, Melissa J Caimano, Isabel C Orbe, Crystal F Vicente, Carson J La Vake, Kelly L Hawley

PLoS Pathog· December 2024

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New Pathways in Syphilis Vaccine Development.
Andy Liu, Lorenzo Giacani, Kelly L Hawley, Caroline E Cameron, Arlene C Seña

Sex Transm Dis· November 2024

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Development and utilization of expressing green fluorescent protein to study spirochete-host interactions and antibody-mediated clearance: expanding the toolbox for syphilis research.
Kristina N Delgado, Crystal F Vicente, Christopher M Hennelly, Farhang Aghakhanian, Jonathan B Parr, Kelly L Hawley

bioRxiv· October 2024

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Clinical and genomic diversity of Treponema pallidum subspecies pallidum to inform vaccine research: an international, molecular epidemiology study.
Arlene C Seña, Mitch M Matoga, Ligang Yang, Eduardo Lopez-Medina, Farhang Aghakhanian, Kelly L Hawley

Lancet Microbe· September 2024

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Treponema pallidum Periplasmic and Membrane Proteins Are Recognized by Circulating and Skin CD4+ T Cells.
Tara B Reid, Charmie Godornes, Victoria L Campbell, Kerry J Laing, Lauren C Tantalo, Kelly L Hawley

J Infect Dis· August 2024

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Treponema pallidum genetic diversity and its implications for targeted vaccine development: A cross-sectional study of early syphilis cases in Southwestern Colombia.
Juan C Salazar, Fabio Vargas-Cely, Jonny A García-Luna, Lady G Ramirez, Everton B Bettin, Kelly L Hawley

PLoS One· July 2024

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Immunodominant extracellular loops of FadL outer membrane proteins elicit antibodies with opsonic and growth-inhibitory activities.
Kristina N Delgado, Melissa J Caimano, Isabel C Orbe, Crystal F Vicente, Carson J La Vake, Kelly L Hawley

bioRxiv· July 2024

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periplasmic and membrane proteins are recognized by circulating and skin CD4+ T cells.
Tara B Reid, Charmie Godornes, Victoria L Campbell, Kerry J Laing, Lauren C Tantalo, Kelly L Hawley

bioRxiv· February 2024

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Early syphilis in Guangzhou, China: presentation, molecular detection of , and genomic sequences in clinical specimens and isolates obtained by rabbit infectivity testing.
Ligang Yang, Xiaohui Zhang, Wentao Chen, Arlene C Seña, Heping Zheng, Kelly L Hawley

medRxiv· October 2023

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Use of Epivolve phage display to generate a monoclonal antibody with opsonic activity directed against a subdominant epitope on extracellular loop 4 of BamA (TP0326).
Mary R Ferguson, Kristina N Delgado, Shannon McBride, Isabel C Orbe, Carson J La Vake, Kelly L Hawley

Front Immunol· September 2023

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Clinical and genomic diversity of A global, multi-center study of early syphilis to inform vaccine research.
Arlene C Seña, Mitch M Matoga, Ligang Yang, Eduardo Lopez-Medina, Farhang Aghakanian, Kelly L Hawley

medRxiv· July 2023

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High-throughput nanopore sequencing of tandem repeat genes and reveals clade-specific patterns and recapitulates global whole genome phylogeny.
Nicole A P Lieberman, Thaddeus D Armstrong, Benjamin Chung, Daniel Pfalmer, Christopher M Hennelly, Kelly L Hawley

Front Microbiol· September 2022

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Extracellular Loops of the Treponema pallidum FadL Orthologs TP0856 and TP0858 Elicit IgG Antibodies and IgG-Specific B-Cells in the Rabbit Model of Experimental Syphilis.
Kristina N Delgado, Jairo M Montezuma-Rusca, Isabel C Orbe, Melissa J Caimano, Carson J La Vake, Kelly L Hawley

mBio· August 2022

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A suite of PCR-LwCas13a assays for detection and genotyping of Treponema pallidum in clinical samples.
Wentao Chen, Hao Luo, Lihong Zeng, Yuying Pan, Jonathan B Parr, Kelly L Hawley

Nat Commun· August 2022

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Structural Modeling of the Treponema pallidum Outer Membrane Protein Repertoire: a Road Map for Deconvolution of Syphilis Pathogenesis and Development of a Syphilis Vaccine.
Kelly L Hawley, Jairo M Montezuma-Rusca, Kristina N Delgado, Navreeta Singh, Vladimir N Uversky

J Bacteriol· July 2021

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Macrophage mediated recognition and clearance of Borrelia burgdorferi elicits MyD88-dependent and -independent phagosomal signals that contribute to phagocytosis and inflammation.
Sarah J Benjamin, Kelly L Hawley, Paola Vera-Licona, Carson J La Vake, Jorge L Cervantes

BMC Immunol· May 2021

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Analysis of Treponema pallidum Strains From China Using Improved Methods for Whole-Genome Sequencing From Primary Syphilis Chancres.
Wentao Chen, David Šmajs, Yongfei Hu, Wujian Ke, Petra Pospíšilová, Kelly L Hawley

J Infect Dis· March 2021

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Evidence that immunization with TP0751, a bipartite Treponema pallidum lipoprotein with an intrinsically disordered region and lipocalin fold, fails to protect in the rabbit model of experimental syphilis.
Amit Luthra, Jairo M Montezuma-Rusca, Carson J La Vake, Morgan LeDoyt, Kristina N Delgado, Kelly L Hawley

PLoS Pathog· September 2020

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