Publications by authors named "Kenneth G Smith"

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Loss of T follicular regulatory cell-derived IL-1R2 augments germinal center reactions via increased IL-1.
Katerina Pyrillou, Melanie Humphry, Lauren A Kitt, Amanda Rodgers, Meritxell Nus, Kenneth Gc Smith

JCI Insight· February 2024

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Identification of new risk loci shared across systemic vasculitides points towards potential target genes for drug repurposing.
Lourdes Ortiz-Fernández, Elio G Carmona, Martin Kerick, Paul Lyons, Francisco David Carmona, Kenneth Gc Smith

Ann Rheum Dis· June 2023

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Effective control of SARS-CoV-2 transmission between healthcare workers during a period of diminished community prevalence of COVID-19.
Nick K Jones, Lucy Rivett, Dominic Sparkes, Sally Forrest, Sushmita Sridhar, Kenneth Gc Smith

Elife· June 2020

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Resolving mechanisms of immune-mediated disease in primary CD4 T cells.
Christophe Bourges, Abigail F Groff, Oliver S Burren, Chiara Gerhardinger, Kaia Mattioli, Kenneth Gc Smith

EMBO Mol Med· May 2020

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Screening of healthcare workers for SARS-CoV-2 highlights the role of asymptomatic carriage in COVID-19 transmission.
Lucy Rivett, Sushmita Sridhar, Dominic Sparkes, Matthew Routledge, Nick K Jones, Kenneth Gc Smith

Elife· May 2020

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Genome-wide association studies in Crohn's disease: Past, present and future.
Bram Verstockt, Kenneth Gc Smith, James C Lee

Clin Transl Immunology· January 2018

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NBEAL2 is required for neutrophil and NK cell function and pathogen defense.
John M Sowerby, David C Thomas, Simon Clare, Marion Espéli, Jose A Guerrero, Kenneth Gc Smith

J Clin Invest· September 2017

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Peripheral Immune Cell Populations Associated with Cognitive Deficits and Negative Symptoms of Treatment-Resistant Schizophrenia.
Emilio Fernandez-Egea, Petra E Vértes, Shaun M Flint, Lorinda Turner, Syed Mustafa, Kenneth G C Smith

PLoS One· July 2017

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Eros is a novel transmembrane protein that controls the phagocyte respiratory burst and is essential for innate immunity.
David C Thomas, Simon Clare, John M Sowerby, Mercedes Pardo, Jatinder K Juss, Kenneth G C Smith

J Exp Med· April 2017

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Genome-wide association study identifies distinct genetic contributions to prognosis and susceptibility in Crohn's disease.
James C Lee, Daniele Biasci, Rebecca Roberts, Richard B Gearry, John C Mansfield, Kenneth G C Smith

Nat Genet· February 2017

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T cell exhaustion and immune-mediated disease-the potential for therapeutic exhaustion.
Eoin F McKinney, Kenneth Gc Smith

Curr Opin Immunol· December 2016

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T-cell exhaustion: understanding the interface of chronic viral and autoinflammatory diseases.
Eoin F McKinney, Kenneth Gc Smith

Immunol Cell Biol· November 2016

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Association Between Genetic Variation in FOXO3 and Reductions in Inflammation and Disease Activity in Inflammatory Polyarthritis.
Sebastien Viatte, James C Lee, Bo Fu, Marion Espéli, Mark Lunt, Kenneth G C Smith

Arthritis Rheumatol· November 2016

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Novel aspects of autoimmunity.
Kenneth Gc Smith, Arthur Kaser

Immunol Cell Biol· November 2016

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Targeted genomic analysis reveals widespread autoimmune disease association with regulatory variants in the TNF superfamily cytokine signalling network.
Arianne C Richard, James E Peters, James C Lee, Golnaz Vahedi, Alejandro A Schäffer, Kenneth G C Smith

Genome Med· July 2016

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Leucocyte subset-specific type 1 interferon signatures in SLE and other immune-mediated diseases.
Shaun M Flint, Vojislav Jovanovic, Boon Wee Teo, Anselm Mak, Julian Thumboo, Kenneth Gc Smith

RMD Open· June 2016

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The Contribution of Transcriptomics to Biomarker Development in Systemic Vasculitis and SLE.
Shaun M Flint, Eoin F McKinney, Paul A Lyons, Kenneth G C Smith

Curr Pharm Des· May 2016

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Insight into Genotype-Phenotype Associations through eQTL Mapping in Multiple Cell Types in Health and Immune-Mediated Disease.
James E Peters, Paul A Lyons, James C Lee, Arianne C Richard, Mary D Fortune, Kenneth G C Smith

PLoS Genet· March 2016

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MT-HESS: an efficient Bayesian approach for simultaneous association detection in OMICS datasets, with application to eQTL mapping in multiple tissues.
Alex Lewin, Habib Saadi, James E Peters, Aida Moreno-Moral, James C Lee, Kenneth G C Smith

Bioinformatics· February 2016

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FcγRIIB and autoimmunity.
Marion Espéli, Kenneth G C Smith, Menna R Clatworthy

Immunol Rev· January 2016

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How many memories does it take to make an SLE flare?
David M Tarlinton, Kenneth G C Smith

Nat Immunol· July 2015

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T-cell exhaustion, co-stimulation and clinical outcome in autoimmunity and infection.
Eoin F McKinney, James C Lee, David R W Jayne, Paul A Lyons, Kenneth G C Smith

Nature· July 2015

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Emerging concepts in the pathogenesis of antineutrophil cytoplasmic antibody-associated vasculitis.
Shaun M Flint, Eoin F McKinney, Kenneth G C Smith

Curr Opin Rheumatol· March 2015

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Randomized trial of enteric-coated mycophenolate sodium versus mycophenolate mofetil in multi-system autoimmune disease.
Rachel B Jones, Michael Walsh, Afzal N Chaudhry, Kenneth G C Smith, David R W Jayne

Clin Kidney J· December 2014

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