Publications by authors named "Kenneth Kellar"

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Pharmacological target sites for restoration of age-associated deficits in NMDA receptor-mediated norepinephrine release in brain.
Yousef Aljohani, William Payne, Robert P Yasuda, Thao Olson, Kenneth J Kellar

J Neurochem· January 2025

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Restoration of norepinephrine release, cognitive performance, and dendritic spines by amphetamine in aged rat brain.
Serena Scognamiglio, Yousef M Aljohani, Thao T Olson, Patrick A Forcelli, Ghazaul Dezfuli, Kenneth J Kellar

Aging Cell· April 2024

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Venlafaxine Stimulates an MMP-9-Dependent Increase in Excitatory/Inhibitory Balance in a Stress Model of Depression.
Seham Alaiyed, Mondona McCann, Gouri Mahajan, Grazyna Rajkowska, Craig A Stockmeier, Kenneth J Kellar

J Neurosci· May 2020

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α4β2 nicotinic acetylcholine receptors intrinsically influence body weight in mice.
Ghazaul Dezfuli, Thao T Olson, Lukas M Martin, Youngshin Keum, Byron A Siegars, Kenneth J Kellar

Neuropharmacology· April 2020

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Oral sazetidine-A, a selective α4β2* nicotinic receptor desensitizing agent, reduces nicotine self-administration in rats.
Amir H Rezvani, Corinne Wells, Susan Slade, Yingxian Xiao, Kenneth J Kellar

Pharmacol Biochem Behav· April 2019

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α4β2 Nicotinic receptor desensitizing compounds can decrease self-administration of cocaine and methamphetamine in rats.
Edward D Levin, Amir H Rezvani, Corinne Wells, Susan Slade, Venkata M Yenugonda, Kenneth J Kellar

Eur J Pharmacol· February 2019

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Effects of nicotine-containing and "nicotine-free" e-cigarette refill liquids on intracranial self-stimulation in rats.
Andrew C Harris, Peter Muelken, John R Smethells, Katrina Yershova, Irina Stepanov, Kenneth J Kellar

Drug Alcohol Depend· April 2018

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Differential efficacies of the nicotinic α4β2 desensitizing agents in reducing nicotine self-administration in female rats.
Amir H Rezvani, Susan Slade, Corinne Wells, Venkata M Yenugonda, Yong Liu, Kenneth J Kellar

Psychopharmacology (Berl)· September 2017

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The (4)(2) Stoichiometry of the Nicotinic Acetylcholine Receptor Predominates in the Rat Motor Cortex.
Kristen E DeDominicis, Niaz Sahibzada, Thao T Olson, Yingxian Xiao, Barry B Wolfe, Kenneth J Kellar

Mol Pharmacol· September 2017

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Evidence for the role of β2* nAChR desensitization in regulating body weight in obese mice.
Ghazaul Dezfuli, Kenneth J Kellar, Kenneth L Dretchen, Yousef Tizabi, Niaz Sahibzada

Neuropharmacology· November 2016

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Anxiolytic- and antidepressant-like effects of the methadone metabolite 2-ethyl-5-methyl-3,3-diphenyl-1-pyrroline (EMDP).
Patrick A Forcelli, Jill R Turner, Bridgin G Lee, Thao T Olson, Teresa Xie, Kenneth J Kellar

Neuropharmacology· February 2016

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AT-1001 Is a Partial Agonist with High Affinity and Selectivity at Human and Rat α3β4 Nicotinic Cholinergic Receptors.
Edward W Tuan, Andrew G Horti, Thao T Olson, Yongiun Gao, Craig A Stockmeier, Kenneth J Kellar

Mol Pharmacol· October 2015

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Menthol Enhances the Desensitization of Human α3β4 Nicotinic Acetylcholine Receptors.
Hoai T Ton, Amanda E Smart, Brittany L Aguilar, Thao T Olson, Kenneth J Kellar

Mol Pharmacol· August 2015

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[(125)I]Iodo-ASEM, a specific in vivo radioligand for α7-nAChR.
Yongjun Gao, Ronnie C Mease, Thao T Olson, Kenneth J Kellar, Robert F Dannals

Nucl Med Biol· May 2015

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Synthesis and pharmacological characterization of new neuronal nicotinic acetylcholine receptor ligands derived from Sazetidine-A.
Yong Liu, Mikell Paige, Thao T Olson, Nour Al-Muhtasib, Teresa Xie, Kenneth J Kellar

Bioorg Med Chem Lett· July 2014

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Chronic sazetidine-A maintains anxiolytic effects and slower weight gain following chronic nicotine without maintaining increased density of nicotinic receptors in rodent brain.
G Patrick Hussmann, Kristen E DeDominicis, Jill R Turner, Robert P Yasuda, Jacquelyn Klehm, Kenneth J Kellar

J Neurochem· May 2014

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18F-ASEM, a radiolabeled antagonist for imaging the α7-nicotinic acetylcholine receptor with PET.
Andrew G Horti, Yongjun Gao, Hiroto Kuwabara, Yuchuan Wang, Sofya Abazyan, Kenneth J Kellar

J Nucl Med· April 2014

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Design, synthesis and discovery of picomolar selective α4β2 nicotinic acetylcholine receptor ligands.
Venkata M Yenugonda, Yingxian Xiao, Edward D Levin, Amir H Rezvani, Thao Tran, Kenneth J Kellar

J Med Chem· November 2013

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Effects of the sazetidine-a family of compounds on the body temperature in wildtype, nicotinic receptor β2-/- and α7-/- mice.
Edward D Levin, Hannah G Sexton, Karen Gordon, Christopher J Gordon, Yingxian Xiao, Kenneth J Kellar

Eur J Pharmacol· October 2013

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Derivatives of dibenzothiophene for positron emission tomography imaging of α7-nicotinic acetylcholine receptors.
Yongjun Gao, Kenneth J Kellar, Robert P Yasuda, Thao Tran, Yingxian Xiao

J Med Chem· October 2013

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Chemistry and pharmacological studies of 3-alkoxy-2,5-disubstituted-pyridinyl compounds as novel selective α4β2 nicotinic acetylcholine receptor ligands that reduce alcohol intake in rats.
Yong Liu, Janell Richardson, Thao Tran, Nour Al-Muhtasib, Teresa Xie, Kenneth J Kellar

J Med Chem· April 2013

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Effects of chronic sazetidine-A, a selective α4β2 neuronal nicotinic acetylcholine receptors desensitizing agent on pharmacologically-induced impaired attention in rats.
Amir H Rezvani, Marty Cauley, Yingxian Xiao, Kenneth J Kellar, Edward D Levin

Psychopharmacology (Berl)· March 2013

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A new radioligand binding assay to measure the concentration of drugs in rodent brain ex vivo.
G Patrick Hussmann, Kenneth J Kellar

J Pharmacol Exp Ther· November 2012

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Chronic sazetidine-A at behaviorally active doses does not increase nicotinic cholinergic receptors in rodent brain.
G Patrick Hussmann, Jill R Turner, Ermelinda Lomazzo, Rashmi Venkatesh, Vanessa Cousins, Kenneth J Kellar

J Pharmacol Exp Ther· November 2012

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Effects of sazetidine-A, a selective α4β2* nicotinic receptor desensitizing agent, on body temperature regulation in mice and rats.
Amir H Rezvani, Olga Timofeeva, Hannah G Sexton, Damien DeCuir, Yingxian Xiao, Kenneth J Kellar

Eur J Pharmacol· May 2012

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