Publications by authors named "Kenton Swartz"

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Mechanisms of ligand recognition and channel opening for P2X2 receptors in lipid nanodiscs.
Surbhi Dhingra, Maia Moog, Kenton J Swartz

bioRxiv· December 2025

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Structural basis of fast N-type inactivation in K channels.
Xiao-Feng Tan, Ana I Fernández-Mariño, Yan Li, Tsg-Hui Chang, Kenton J Swartz

Nature· September 2025

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Conservation of the cooling agent binding pocket within the TRPM subfamily.
Kate Huffer, Matthew C S Denley, Elisabeth V Oskoui, Kenton J Swartz

Elife· November 2024

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Conservation of the cooling agent binding pocket within the TRPM subfamily.
Kate Huffer, Matthew C S Denley, Elisabeth V Oskoui, Kenton J Swartz

bioRxiv· August 2024

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Dilation of ion selectivity filters in cation channels.
Kate Huffer, Xiao-Feng Tan, Ana I Fernández-Mariño, Surbhi Dhingra, Kenton J Swartz

Trends Biochem Sci· May 2024

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Eukaryotic Kv channel Shaker inactivates through selectivity filter dilation rather than collapse.
Robyn Stix, Xiao-Feng Tan, Chanhyung Bae, Ana I Fernández-Mariño, Kenton J Swartz

Sci Adv· December 2023

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Inactivation of the Kv2.1 channel through electromechanical coupling.
Ana I Fernández-Mariño, Xiao-Feng Tan, Chanhyung Bae, Kate Huffer, Jiansen Jiang, Kenton J Swartz

Nature· October 2023

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Cannabidiol sensitizes TRPV2 channels to activation by 2-APB.
Aaron Gochman, Xiao-Feng Tan, Chanhyung Bae, Helen Chen, Kenton J Swartz

Elife· May 2023

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Ion permeation pathway within the internal pore of P2X receptor channels.
Stephanie W Tam, Kate Huffer, Mufeng Li, Kenton J Swartz

Elife· March 2023

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Cannabidiol sensitizes TRPV2 channels to activation by 2-APB.
Aaron Gochman, Xiaofeng Tan, Chanhyung Bae, Helen Chen, Kenton J Swartz

bioRxiv· January 2023

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Mutations within the selectivity filter reveal that Kv1 channels have distinct propensities to slow inactivate.
Xiaosa Wu, Kanchan Gupta, Kenton J Swartz

J Gen Physiol· November 2022

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Regulation of membrane homeostasis by TMC1 mechanoelectrical transduction channels is essential for hearing.
Angela Ballesteros, Kenton J Swartz

Sci Adv· August 2022

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Structures of the T cell potassium channel Kv1.3 with immunoglobulin modulators.
Purushotham Selvakumar, Ana I Fernández-Mariño, Nandish Khanra, Changhao He, Alice J Paquette, Kenton J Swartz

Nat Commun· July 2022

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Structure of the Shaker Kv channel and mechanism of slow C-type inactivation.
Xiao-Feng Tan, Chanhyung Bae, Robyn Stix, Ana I Fernández-Mariño, Kate Huffer, Kenton J Swartz

Sci Adv· March 2022

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Expression of a membrane-targeted fluorescent reporter disrupts auditory hair cell mechanoelectrical transduction and causes profound deafness.
Angela Ballesteros, Tracy S Fitzgerald, Kenton J Swartz

Hear Res· May 2021

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Global alignment and assessment of TRP channel transmembrane domain structures to explore functional mechanisms.
Katherine E Huffer, Antoniya A Aleksandrova, Andrés Jara-Oseguera, Lucy R Forrest, Kenton J Swartz

Elife· August 2020

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Dextran Labeling and Uptake in Live and Functional Murine Cochlear Hair Cells.
Angela Ballesteros, Kenton J Swartz

J Vis Exp· February 2020

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Hearing loss mutations alter the functional properties of human P2X2 receptor channels through distinct mechanisms.
Benjamin George, Kenton J Swartz, Mufeng Li

Proc Natl Acad Sci U S A· November 2019

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Exploring structural dynamics of a membrane protein by combining bioorthogonal chemistry and cysteine mutagenesis.
Kanchan Gupta, Gilman Es Toombes, Kenton J Swartz

Elife· November 2019

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The ion selectivity filter is not an activation gate in TRPV1-3 channels.
Andrés Jara-Oseguera, Katherine E Huffer, Kenton J Swartz

Elife· November 2019

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Molecular mechanisms of human P2X3 receptor channel activation and modulation by divalent cation bound ATP.
Mufeng Li, Yao Wang, Rahul Banerjee, Fabrizio Marinelli, Shai Silberberg, Kenton Jon Swartz

Elife· June 2019

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TMEM266 is a functional voltage sensor regulated by extracellular Zn.
Ferenc Papp, Suvendu Lomash, Orsolya Szilagyi, Erika Babikow, Jaime Smith, Kenton Jon Swartz

Elife· February 2019

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Conserved allosteric pathways for activation of TRPV3 revealed through engineering vanilloid-sensitivity.
Feng Zhang, Kenton Jon Swartz, Andres Jara-Oseguera

Elife· January 2019

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Single-particle cryo-EM structure of a voltage-activated potassium channel in lipid nanodiscs.
Doreen Matthies, Chanhyung Bae, Gilman Es Toombes, Tara Fox, Alberto Bartesaghi, Kenton Jon Swartz

Elife· August 2018

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Structural relationship between the putative hair cell mechanotransduction channel TMC1 and TMEM16 proteins.
Angela Ballesteros, Cristina Fenollar-Ferrer, Kenton Jon Swartz

Elife· July 2018

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