Publications by authors named "Kevork Hagopian"

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A Ketogenic Diet Extends Longevity and Healthspan in Adult Mice.
Megan N Roberts, Marita A Wallace, Alexey A Tomilov, Zeyu Zhou, George R Marcotte, Dianna Tran, Gabriella Perez, Elena Gutierrez-Casado, Shinichiro Koike, Trina A Knotts

September 2017

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A ketogenic diet impacts markers of mitochondrial mass in a tissue specific manner in aged mice.
Zeyu Zhou, Kevork Hagopian, José A López-Domínguez, Kyoungmi Kim, Mittal Jasoliya

Aging (Albany NY)· March 2021

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A Ketogenic Diet Extends Longevity and Healthspan in Adult Mice.
Megan N Roberts, Marita A Wallace, Alexey A Tomilov, Zeyu Zhou, George R Marcotte, Kevork Hagopian

Cell Metab· May 2018

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Mice with low levels of Shc proteins display reduced glycolytic and increased gluconeogenic activities in liver.
Kevork Hagopian, Kyoungmi Kim, José Alberto López-Dominguez, Alexey A Tomilov, Gino A Cortopassi

Biochem Biophys Rep· September 2016

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p46Shc Inhibits Thiolase and Lipid Oxidation in Mitochondria.
Alexey Tomilov, Natalia Tomilova, Yuxi Shan, Kevork Hagopian, Ahmed Bettaieb

J Biol Chem· June 2016

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Key glycolytic enzyme activities of skeletal muscle are decreased under fed and fasted states in mice with knocked down levels of Shc proteins.
Kevork Hagopian, Alexey A Tomilov, Kyoungmi Kim, Gino A Cortopassi, Jon J Ramsey

PLoS One· April 2016

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The Influence of Dietary Fat Source on Life Span in Calorie Restricted Mice.
José A López-Domínguez, Jon J Ramsey, Dianna Tran, Denise M Imai, Amanda Koehne, Kevork Hagopian

J Gerontol A Biol Sci Med Sci· October 2015

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The influence of dietary fat source on liver and skeletal muscle mitochondrial modifications and lifespan changes in calorie-restricted mice.
José Manuel Villalba, José Alberto López-Domínguez, Yana Chen, Husam Khraiwesh, José Antonio González-Reyes, Kevork Hagopian

Biogerontology· October 2015

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Shc depletion stimulates brown fat activity in vivo and in vitro.
Alexey Tomilov, Ahmed Bettaieb, Kyoungmi Kim, Sunil Sahdeo, Natalia Tomilova, Kevork Hagopian

Aging Cell· December 2014

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The influence of Shc proteins on life span in mice.
Jon J Ramsey, Dianna Tran, Marco Giorgio, Stephen M Griffey, Amanda Koehne, Kevork Hagopian

J Gerontol A Biol Sci Med Sci· October 2014

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Calorie restriction influences key metabolic enzyme activities and markers of oxidative damage in distinct mouse liver mitochondrial sub-populations.
Kevork Hagopian, Robert Soo Hoo, José A López-Domínguez, Jon J Ramsey

Life Sci· December 2013

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Shc proteins influence the activities of enzymes involved in fatty acid oxidation and ketogenesis.
Kevork Hagopian, Alexey A Tomilov, Natalia Tomilova, Kyoungmi Kim, Sandra L Taylor

Metabolism· December 2012

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The influence of dietary lipid composition on liver mitochondria from mice following 1 month of calorie restriction.
Yana Chen, Kevork Hagopian, Douglas Bibus, José M Villalba, Guillermo López-Lluch

Biosci Rep· December 2012

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The influence of dietary lipid composition on skeletal muscle mitochondria from mice following 1 month of calorie restriction.
Yana Chen, Kevork Hagopian, Roger B McDonald, Douglas Bibus, Guillermo López-Lluch

J Gerontol A Biol Sci Med Sci· November 2012

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The p66Shc knocked out mice are short lived under natural condition.
Marco Giorgio, Alessandra Berry, Ina Berniakovich, Inga Poletaeva, Mirella Trinei, Kevork Hagopian

Aging Cell· February 2012

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Caloric restriction influences hydrogen peroxide generation in mitochondrial sub-populations from mouse liver.
Kevork Hagopian, Yana Chen, Keira Simmons Domer, Robert Soo Hoo, Trevor Bentley

J Bioenerg Biomembr· June 2011

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The Shc locus regulates insulin signaling and adiposity in mammals.
Alexey A Tomilov, Jon J Ramsey, Kevork Hagopian, Marco Giorgio, Kyoungmi M Kim

Aging Cell· February 2011

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Complex I-associated hydrogen peroxide production is decreased and electron transport chain enzyme activities are altered in n-3 enriched fat-1 mice.
Kevork Hagopian, Kristina L Weber, Darren T Hwee, Alison L Van Eenennaam, Guillermo López-Lluch

PLoS One· September 2010

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Decreased superoxide production in macrophages of long-lived p66Shc knock-out mice.
Alexey A Tomilov, Vincent Bicocca, Robert A Schoenfeld, Marco Giorgio, Enrica Migliaccio, Kevork Hagopian

J Biol Chem· January 2010

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Caloric restriction counteracts age-related changes in the activities of sorbitol metabolizing enzymes from mouse liver.
Kevork Hagopian, Jon J Ramsey, Richard Weindruch

Biogerontology· August 2009

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Effect of aging, caloric restriction, and uncoupling protein 3 (UCP3) on mitochondrial proton leak in mice.
Danny K Asami, Roger B McDonald, Kevork Hagopian, Barbara A Horwitz, David Warman

Exp Gerontol· December 2008

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Enzymes of glycerol and glyceraldehyde metabolism in mouse liver: effects of caloric restriction and age on activities.
Kevork Hagopian, Jon J Ramsey, Richard Weindruch

Biosci Rep· April 2008

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Rat liver xanthine oxidoreductase: effect of adenine on the oxidase and dehydrogenase activities.
Kevork Hagopian

Ital J Biochem· March 2007

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Energy expenditure and restriction of energy intake: could energy restriction alter energy expenditure in companion animals?
Jon J Ramsey, Kevork Hagopian

J Nutr· July 2006

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Long-term caloric restriction increases UCP3 content but decreases proton leak and reactive oxygen species production in rat skeletal muscle mitochondria.
Lisa Bevilacqua, Jon J Ramsey, Kevork Hagopian, Richard Weindruch, Mary-Ellen Harper

Am J Physiol Endocrinol Metab· September 2005

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