Publications by authors named "Khalid Chakir"

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Photobiomodulation therapy mitigates cardiovascular aging and improves survival.
Sunayana Begum Syed, Ismayil Ahmet, Khalid Chakir, Christopher H Morrell, Praveen R Arany, Edward G Lakatta

Lasers Surg Med· March 2023

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Failure of efficient cardiac proteostatic adaptations to chronic cAMP-stress is associated with accelerated heart aging.
Maria Grazia Perino, Miguel Calvo-Rubio Barrera, Daniel R Riordon, Giulio Agnetti, Alexander Maltsev, Khalid Chakir

Geroscience· September 2025

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Reprogramming of cardiac phosphoproteome, proteome, and transcriptome confers resilience to chronic adenylyl cyclase-driven stress.
Jia-Hua Qu, Khalid Chakir, Kirill V Tarasov, Daniel R Riordon, Maria Grazia Perino

Elife· January 2024

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Transcriptome of Left Ventricle and Sinoatrial Node in Young and Old C57 Mice.
Jia-Hua Qu, Kirill V Tarasov, Yelena S Tarasova, Khalid Chakir, Edward G Lakatta

Fortune J Health Sci· September 2023

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A remarkable adaptive paradigm of heart performance and protection emerges in response to marked cardiac-specific overexpression of ADCY8.
Kirill V Tarasov, Khalid Chakir, Daniel R Riordon, Alexey E Lyashkov, Ismayil Ahmet

Elife· December 2022

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Proteomic Landscape and Deduced Functions of the Cardiac 14-3-3 Protein Interactome.
Jia-Hua Qu, Kirill V Tarasov, Khalid Chakir, Yelena S Tarasova, Daniel R Riordon

Cells· November 2022

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Overexpression of a Neuronal Type Adenylyl Cyclase (Type 8) in Sinoatrial Node Markedly Impacts Heart Rate and Rhythm.
Jack M Moen, Michael G Matt, Christopher Ramirez, Kirill V Tarasov, Khalid Chakir

Front Neurosci· June 2019

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Basal Spontaneous Firing of Rabbit Sinoatrial Node Cells Is Regulated by Dual Activation of PDEs (Phosphodiesterases) 3 and 4.
Tatiana M Vinogradova, Syevda Sirenko, Yevgeniya O Lukyanenko, Dongmei Yang, Kirill V Tarasov, Khalid Chakir

Circ Arrhythm Electrophysiol· June 2018

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Neonatal Transplantation Confers Maturation of PSC-Derived Cardiomyocytes Conducive to Modeling Cardiomyopathy.
Gun-Sik Cho, Dong I Lee, Emmanouil Tampakakis, Sean Murphy, Peter Andersen, Khalid Chakir

Cell Rep· January 2017

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Saxagliptin and Tadalafil Differentially Alter Cyclic Guanosine Monophosphate (cGMP) Signaling and Left Ventricular Function in Aortic-Banded Mini-Swine.
Jessica A Hiemstra, Dong I Lee, Khalid Chakir, Manuel Gutiérrez-Aguilar, Kurt D Marshall

J Am Heart Assoc· April 2016

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Response to Letter Regarding Article, "Circulating MicroRNA-30d Is Associated With Response to Cardiac Resynchronization Therapy in Heart Failure and Regulates Cardiomyocyte Apoptosis: A Translational Pilot Study".
Yonathan F Melman, Ravi Shah, Kirsty Danielson, Junjie Xiao, Bridget Simonson, Khalid Chakir

Circulation· February 2016

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Pacemaker-induced transient asynchrony suppresses heart failure progression.
Jonathan A Kirk, Khalid Chakir, Kyoung Hwan Lee, Edward Karst, Ronald J Holewinski

Sci Transl Med· December 2015

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Sildenafil treatment attenuates ventricular remodeling in an experimental model of aortic regurgitation.
Kristian Eskesen, Niels Thue Olsen, Veronica L Dimaano, Thomas Fritz-Hansen, Peter Sogaard, Khalid Chakir

Springerplus· November 2015

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Removal of Abnormal Myofilament O-GlcNAcylation Restores Ca2+ Sensitivity in Diabetic Cardiac Muscle.
Genaro A Ramirez-Correa, Junfeng Ma, Chad Slawson, Quira Zeidan, Nahyr S Lugo-Fagundo, Khalid Chakir

Diabetes· October 2015

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Circulating MicroRNA-30d Is Associated With Response to Cardiac Resynchronization Therapy in Heart Failure and Regulates Cardiomyocyte Apoptosis: A Translational Pilot Study.
Yonathan F Melman, Ravi Shah, Kirsty Danielson, Junjie Xiao, Bridget Simonson, Khalid Chakir

Circulation· June 2015

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Desmin modifications associate with amyloid-like oligomers deposition in heart failure.
Giulio Agnetti, Victoria L Halperin, Jonathan A Kirk, Khalid Chakir, Yurong Guo

Cardiovasc Res· April 2014

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Hypertrophy signaling pathways in experimental chronic aortic regurgitation.
Niels Thue Olsen, Veronica L Dimaano, Thomas Fritz-Hansen, Peter Sogaard, Khalid Chakir

J Cardiovasc Transl Res· October 2013

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Cardiac resynchronization therapy improves altered Na channel gating in canine model of dyssynchronous heart failure.
Takeshi Aiba, Andreas S Barth, Geoffrey G Hesketh, Yasmin L Hashambhoy, Khalid Chakir

Circ Arrhythm Electrophysiol· June 2013

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Transcriptome, proteome, and metabolome in dyssynchronous heart failure and CRT.
Andreas S Barth, Khalid Chakir, David A Kass, Gordon F Tomaselli

J Cardiovasc Transl Res· April 2012

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Gi-biased β2AR signaling links GRK2 upregulation to heart failure.
Weizhong Zhu, Natalia Petrashevskaya, Shuxun Ren, Aizhi Zhao, Khalid Chakir

Circ Res· January 2012

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Galphas-biased beta2-adrenergic receptor signaling from restoring synchronous contraction in the failing heart.
Khalid Chakir, Charlene Depry, Veronica L Dimaano, Wei-Zhong Zhu, Marc Vanderheyden

Sci Transl Med· September 2011

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RGS2 is a primary terminator of β₂-adrenergic receptor-mediated G(i) signaling.
Khalid Chakir, Weizhong Zhu, Sharon Tsang, Anthony Yiu-Ho Woo, Dongmei Yang

J Mol Cell Cardiol· June 2011

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Modulation of mitochondrial proteome and improved mitochondrial function by biventricular pacing of dyssynchronous failing hearts.
Giulio Agnetti, Nina Kaludercic, Lesley A Kane, Steven T Elliott, Yurong Guo, Khalid Chakir

Circ Cardiovasc Genet· February 2010

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Rethinking Resynch: Exploring Mechanisms of Cardiac Resynchroniztion Beyond Wall Motion Control.
Khalid Chakir, David A Kass

Drug Discov Today Dis Mech· January 2010

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Cardiac resynchronization therapy corrects dyssynchrony-induced regional gene expression changes on a genomic level.
Andreas S Barth, Takeshi Aiba, Victoria Halperin, Deborah DiSilvestre, Khalid Chakir

Circ Cardiovasc Genet· August 2009

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