Publications by authors named "Kuai Le"

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Immune cells in diabetic wound repair: the key to better wound management.
Yi Ru, Yunxi Cai, Guangyuan Cheng, Xiaoxuan Ma, Jingsi Jiang, Le Kuai

Front Med· December 2025

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CRISPR/Cas9-Mediated Knockout and Overexpression Studies Unveil the Role of PD-L1 in Immune Modulation in a Psoriasis-like Mouse Model.
Chunjie Gao, Yunxi Cai, Xinxin Wu, Jiankun Song, Qi Zheng, Le Kuai

Inflammation· October 2025

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Beyond Skin Clearance: Personalized Strategies for DLQI Improvement in Psoriasis -Insights From a Shanghai Prospective Cohort.
Xin Ma, Quanruo Xu, Le Kuai, Fanlingzi Shen, Zhen Duan

Psoriasis (Auckl)· September 2025

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An approach for psoriasis of microneedle patch simultaneously targeting multiple inflammatory cytokines and relapse related T cells.
Li Huang, Ying Luo, Le Kuai, Xiaoyou Zhang, Ying Zhang

Biomaterials· July 2025

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Prim-O-glucosylcimifugin mitigates atopic dermatitis by inhibiting Th2 differentiation through LCK phosphorylation modulation.
Hang Zhao, Xin Ma, Hao Wang, Xiao-Jie Ding, Le Kuai

J Integr Med· May 2025

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KGSD-Net: a knowledge graph syndrome differentiation network for syndrome classification.
Guokai Zhang, Haoyu Jiang, Le Kuai, Bin Li, Chenxi Huang

Front Med (Lausanne)· May 2025

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The Role of Lactate and Lactylation in the Dysregulation of Immune Responses in Psoriasis.
Xinxin Wu, Changya Liu, Caiyun Zhang, Le Kuai, Sheng Hu

Clin Rev Allergy Immunol· March 2025

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Efficacy and safety of Kangfuxin liquid for eczema: a systematic review and meta-analysis.
Yi-Ran Chen, Xiao-Fan Yang, Xiao-Jie Ding, Ying Luo, Le Kuai

Arch Dermatol Res· March 2025

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Retracing from Outcomes to Causes: NRF2-Driven GSTA4 Transcriptional Regulation Controls Chronic Inflammation and Oxidative Stress in Atopic Dermatitis Recurrence.
Xin Ma, Hang Zhao, Jian-Kun Song, Zhan Zhang, Chun-Jie Gao, Le Kuai

J Invest Dermatol· February 2025

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Preclinical and clinical studies on Qin-Zhu-Liang-Xue decoction: insights from network pharmacology and implications for atopic dermatitis treatment.
Keke Huang, Qingkai Liu, Ruoxi Zhang, Hua Nian, Ying Luo, Le Kuai

Front Med· February 2025

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Machine Learning-Driven discovery of immunogenic cell Death-Related biomarkers and molecular classification for diabetic ulcers.
Yun-Xi Cai, Shi-Qi Li, Hang Zhao, Miao Li, Ying Zhang, Le Kuai

Gene· January 2025

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Single-Atom Catalysts with Isolated Cu-N Sites for Atopic Dermatitis Cascade Catalytic Therapy via Activating PPAR Signaling.
Le Kuai, Fang Huang, Lijie Mao, Yi Ru, Jingsi Jiang

Small· December 2024

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Adenanthin exhibits anti-inflammatory effects by covalently targeting the p65 subunit in the NF-κB signaling pathway.
Lu Tong, Meng-Li Zha, Junchi Hu, Hai-Yang Li, Le Kuai

Eur J Med Chem· December 2024

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Epidermal keratinocytes-specific PD-L1 knockout causes delayed healing of diabetic wounds.
Zhan Zhang, Dan Yang, Fang Shen, Ting-Ting Xue, Jing-Si Jiang, Le Kuai

Int Immunopharmacol· December 2024

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The role and therapeutic strategies for tissue-resident memory T cells, central memory T cells, and effector memory T cells in psoriasis.
Guoshu Deng, Yulin Zhang, Jiankun Song, Ying Zhang, Qi Zheng, Le Kuai

Immunology· November 2024

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Liquiritin exerts psoriasis therapy and prevention by regulating the YY1/RBP3 axis.
Guoshu Deng, Yulin Zhang, Jiankun Song, Xiaoxuan Ma, Yue Luo, Le Kuai

Phytomedicine· November 2024

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Topical application of Artemisia annua L. essential oil ameliorates 2,4-dintrochlorobenzene-induced atopic dermatitis in mice.
Zhiya Huang, Bin Fan, Weiwei Mao, Le Kuai, Jun Feng

J Ethnopharmacol· October 2024

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Identification of angiogenesis-related genes and molecular subtypes for psoriasis based on random forest algorithm.
Meng-Jie Zhang, Ting-Ting Xue, Xiao-Ya Fei, Ying Zhang, Ying Luo, Le Kuai

Clin Exp Immunol· October 2024

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Terrestrial photosynthesis inferred from plant carbonyl sulfide uptake.
Jiameng Lai, Linda M J Kooijmans, Wu Sun, Danica Lombardozzi, J Elliott Campbell, Le Kuai

Nature· October 2024

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Sirtuin-6 knockout causes exacerbated stalled healing of diabetic ulcers in mice.
Ting-Ting Xue, Hui-Jung Cha, Qing-Kai Liu, Dan Yang, Zhan Zhang, Le Kuai

Biochem Biophys Res Commun· September 2024

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M2 macrophage-polarized anti-inflammatory microneedle patch for accelerating biofilm-infected diabetic wound healing via modulating the insulin pathway.
Yushan Yang, Limin Fan, Jingsi Jiang, Jiuyuan Sun, Liangyi Xue, Le Kuai

J Nanobiotechnology· August 2024

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Exploring the role of autophagy in psoriasis pathogenesis: Insights into sustained inflammation and dysfunctional keratinocyte differentiation.
Xinxin Wu, Jiankun Song, Ying Zhang, Le Kuai, Changya Liu

Int Immunopharmacol· June 2024

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Epidemiology of malignant tumors in patients with pemphigus: an analysis of trends from 1955 to 2021.
Yue Luo, Xiaoya Fei, Mingxia Wang, Han Yang, Ying Zhang, Le Kuai

Clin Exp Med· May 2024

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Tobacco smoking negatively influences the achievement of greater than three-quarters reduction in psoriasis area and severity index after eight weeks of treatment among patients with psoriasis: Findings from a prospective study.
Yan Qiang, Le Kuai, Shuo Liu, Quanruo Xu, Lingzi Shenfan

Tob Induc Dis· April 2024

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