Publications by authors named "Kyle Rohde"

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CRISPRi-mediated validation of candidate drug targets during host infection.
Rashmi Gupta, Breven S Simcox, Kyle H Rohde

bioRxiv· December 2025

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Targeting Mycolic Acid Biosynthesis with Cyclic Sulfamates: A New Strategy against .
Priscila Cristina Bartolomeu Halicki, Jed H Kim, Amory Francis Griffin, Daniel S Rampon, Kindra L Becker, Kyle H Rohde

ACS Infect Dis· November 2025

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Synthesis and evaluation of Trehalose-Pks13 inhibitor conjugates targeting mycobacteria.
Umesha Subhani S Kumbalathara A D, Priscila Cristina Bartolomeu Halicki, Karishma Kalera, Benjamin M Swarts, Kyle H Rohde

Carbohydr Res· July 2025

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Discovery of 2,4,5-Substituted Benzoxazole Derivatives as Pks13 Inhibitors via the Scaffold Hopping Strategy.
Babatunde Samuel Obadawo, Priscila Cristina Bartolomeu Halicki, Kindra L Becker, Jessica C Seeliger, Kyle H Rohde

ACS Infect Dis· June 2025

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persistence in the face of antagonism.
Rashmi Gupta, Martin Schuster, Kyle H Rohde

Front Cell Infect Microbiol· May 2025

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Identification of 6,8-ditrifluoromethyl halogenated phenazine as a potent bacterial biofilm-eradicating agent.
Qiwen Gao, Hongfen Yang, Jeremy Sheiber, Priscila Cristina Bartolomeu Halicki, Ke Liu, Kyle H Rohde

Org Biomol Chem· April 2025

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Atypical Mycobacterium abscessus BlaRI Ortholog Mediates Regulation of Energy Metabolism but Not β-Lactam Resistance.
Lauren E Bonefont, Haley C Davenport, Catherine T Chaton, Konstantin V Korotkov, Kyle H Rohde

Mol Microbiol· October 2024

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Detection of Mtb and NTM: preclinical validation of a new asymmetric PCR-binary deoxyribozyme sensor assay.
Yasmin Castillos das Neves, Ana Julia Reis, Marcos Alaniz Rodrigues, Erica Chimara, Maria Cristina da Silva Lourenço, Kyle H Rohde

Microbiol Spectr· June 2024

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Orphan response regulator NnaR is critical for nitrate and nitrite assimilation in .
Breven S Simcox, Kyle H Rohde

Front Cell Infect Microbiol· June 2024

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DosRS two-component system controls a species-specific regulon required for adaptation to hypoxia.
Breven S Simcox, Brooke R Tomlinson, Lindsey N Shaw, Kyle H Rohde

Front Cell Infect Microbiol· March 2023

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Implementation of a mycobacterial CRISPRi platform in Mycobacterium abscessus and demonstration of the essentiality of ftsZ.
Rashmi Gupta, Kyle H Rohde

Tuberculosis (Edinb)· January 2023

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Proton Motive Force-Disrupting Antimycobacterial Guanylurea Polymer.
Michelle Miranda-Velez, Golam Sabbir Sarker, Priya Ramisetty, Sandra Geden, Priscila Cristina Bartolomeu Halicki, Kyle H Rohde

Biomacromolecules· November 2022

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Synthesis and Evaluation of Marine Natural Product-Inspired Meroterpenoids with Selective Activity toward Dormant .
Anshupriya Si, Alexander D Landgraf, Sandra Geden, Steven J Sucheck, Kyle H Rohde

ACS Omega· July 2022

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Atypically Modified Carbapenem Antibiotics Display Improved Antimycobacterial Activity in the Absence of β-Lactamase Inhibitors.
Rashmi Gupta, Noora M S A Al-Kharji, Maha A Alqurafi, Thu Q Nguyen, Weirui Chai, Kyle H Rohde

ACS Infect Dis· August 2021

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A Modular Synthetic Route Involving -Aryl-2-nitrosoaniline Intermediates Leads to a New Series of 3-Substituted Halogenated Phenazine Antibacterial Agents.
Hongfen Yang, Shivani Kundra, Michaelle Chojnacki, Ke Liu, Marisa A Fuse, Kyle H Rohde

J Med Chem· June 2021

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The Prospective Synergy of Antitubercular Drugs With NAD Biosynthesis Inhibitors.
Kyle H Rohde, Leonardo Sorci

Front Microbiol· January 2021

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Cascade of deoxyribozymes for the colorimetric analysis of drug resistance in Mycobacterium tuberculosis.
Bidhan C Dhar, Adam J Reed, Suvra Mitra, Patricia Rodriguez Sanchez, Daria D Nedorezova, Kyle H Rohde

Biosens Bioelectron· October 2020

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Crystal structure of a hemerythrin-like protein from Mycobacterium kansasii and homology model of the orthologous Rv2633c protein of M. tuberculosis.
Zhongxin Ma, Jan Abendroth, Garry W Buchko, Kyle H Rohde, Victor L Davidson

Biochem J· January 2020

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Growth hormone-mediated reprogramming of macrophage transcriptome and effector functions.
Augusto Schneider, Hillary N Wood, Sandra Geden, Catherine J Greene, Robin M Yates, Kyle H Rohde

Sci Rep· December 2019

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Plakinamine P, A Steroidal Alkaloid with Bactericidal Activity against .
Carolina Rodrigues Felix, Jill C Roberts, Priscilla L Winder, Rashmi Gupta, M Cristina Diaz, Kyle H Rohde

Mar Drugs· December 2019

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Molecular drug susceptibility testing and strain typing of tuberculosis by DNA hybridization.
Hillary N Wood, Tom Venken, Hanny Willems, An Jacobs, Ana Júlia Reis, Kyle H Rohde

PLoS One· November 2019

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Novel Antimycobacterial Compounds Suppress NAD Biogenesis by Targeting a Unique Pocket of NaMN Adenylyltransferase.
Andrei L Osterman, Irina Rodionova, Xiaoqing Li, Eduard Sergienko, Chen-Ting Ma, Kyle H Rohde

ACS Chem Biol· May 2019

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Species Typing of Nontuberculous Mycobacteria by Use of Deoxyribozyme Sensors.
Hillary N Wood, Ashelyn E Sidders, Lauren E Brumsey, Evgeny S Morozkin, Yulia V Gerasimova, Kyle H Rohde

Clin Chem· February 2019

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Exploitation of Mangrove Endophytic Fungi for Infectious Disease Drug Discovery.
Danielle H Demers, Matthew A Knestrick, Renee Fleeman, Rahmy Tawfik, Ala Azhari, Kyle H Rohde

Mar Drugs· October 2018

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Evidence for Inhibition of Topoisomerase 1A by Gold(III) Macrocycles and Chelates Targeting Mycobacterium tuberculosis and Mycobacterium abscessus.
Rashmi Gupta, Carolina Rodrigues Felix, Matthew P Akerman, Kate J Akerman, Cathryn A Slabber, Kyle H Rohde

Antimicrob Agents Chemother· May 2018

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