Publications by authors named "L-Y Han"

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HTRA1/lncRNA HTRA1-AS1 dominates in age-related macular degeneration reticular pseudodrusen genetic risk with no complement involvement.
Samaneh Farashi, Carla J Abbott, Brendan R E Ansell, Zhichao Wu, Lebriz Altay, Jiru Han, Samuel McLenachan

Nat Commun· December 2025

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An innovative engineered IL-10 monomer strengthens T cell-mediated anti-tumor responses through anti-PD-1 cis-delivery.
Ce Gu, Jian Guo, Chang Zhou, Peipei Hu, Xiaodong Wu, Zhe Zhang, Yingpei Zhang, Zhe Han

Cell Rep Med· December 2025

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A 3D in vitro model for studying human implantation and implantation failure.
Qian Li, Yang Yuan, Wentao Zhao, Yuanjun Li, Juanzi Shi, Mi Han, Yan Han, Junmei Zhang, Shuhan Cheng

Cell· December 2025

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Phase 1 Study of Luvometinib Use in Pediatric Patients with Neurofibromatosis Type 1-Related Unresectable Plexiform Neurofibromas.
Xiaojie Hu, Zhuli Wu, Jinhu Wang, Wenbin Li, Kang Zeng, Pu Han, Changxing Li

Target Oncol· November 2025

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MRI-based Habitat Imaging for Noninvasive Prediction of High-Grade Prostate Cancer.
Lei Yuan, Jingliang Zhang, Lina Ma, Yuwei Xia, Ye Han, Jing Zhang

Radiol Imaging Cancer· November 2025

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Spinal cord Tau pathology induces tactile deficits and cognitive impairment in Alzheimer's disease via dysregulation of CCK neurons.
Yang Zhou, Wen-Lian Li, Zhi-Qiang Liu, Wen-Qing Ai, Jia-Xin Kou, Zhi-Tao Han, Hong-Hong Zhang

Nat Neurosci· November 2025

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Reproducible and later vaccine strain selection can improve vaccine match to A/H3N2 seasonal influenza viruses.
Annelies J H de Rooij, Vincent J C Lempers, Yoonyoung Park, Nevena Vicic, Alvin X Han

NPJ Vaccines· November 2025

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Lac-Phe induces hypophagia by inhibiting AgRP neurons in mice.
Hailan Liu, Veronica L Li, Qingzhuo Liu, Yao Liu, Cunjin Su, Jonathan C Bean, Yuhan Shi, Junying Han, Jonathan Z Long

Nat Metab· October 2025

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Maximal Oxygen Uptake and Coronary Artery Calcium Scores in Firefighters.
Mingyue Li, Jiali Han, Carolyn Muegge, Terrell Zollinger, Laura Y Zhou, Patrick Monahan

J Occup Environ Med· September 2025

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Deep Learning Based Multiomics Model for Risk Stratification of Postoperative Distant Metastasis in Colorectal Cancer.
Xiuzhen Yao, Xiaoyu Han, Danjiang Huang, Yongfei Zheng, Shuitang Deng

Acad Radiol· September 2025

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JARID2 Inhibition Reprograms Human Hematopoietic Progenitor Cells To Enhance Bone Marrow Transplantation.
Wentao Han, Hassan Bjeije, Hamza Celik, Michael Rettig, Nancy Issa, Christine R Zhang

bioRxiv· September 2025

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Intranasal vaccine combining adenovirus and trimeric subunit protein provides superior immunity against SARS-CoV-2 Omicron variant.
Weiqi Hong, Ping Cheng, Jingyun Yang, Huashan Shi, Zhenling Wang, Binhan Wang, Yu Zhang, Xuejiao Han

Nat Biomed Eng· September 2025

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Disruption of cTnT-Mediated Sarcomere-Mitochondrial Communication Results in Dilated Cardiomyopathy.
Lingqun Ye, Junwei Liu, Wei Lei, Baoqiang Ni, Xinglong Han, Yan Zhang, Jianyi Zhang

Circulation· August 2025

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Non-canonical functions of DNMT3A in hematopoietic stem cells regulate telomerase activity and genome integrity.
Infencia Xavier Raj, Won Kyun Koh, Jessica Harrison, Christine R Zhang, Barbara Soares, Wentao Han

Cell Stem Cell· August 2025

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Downregulated Expression of Serum Exosome-Derived miR-375-3p Alleviates Interface Hepatitis and Promotes Fibrosis Regression in Patients With Chronic Hepatitis B.
Ran Xu, Sihao Wang, Quanwei He, Wei Han, Shujuan Gong, Xiaoyan Zhan

Clin Transl Gastroenterol· July 2025

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Traction-Free Arthroscopy Using an Inside-Out Technique for Treating Femoroacetabular Impingement Syndrome.
Lingchao Ye, Xiangang Jin, Huixia Fan, Qingguo Zhang, Pangtao Chen, Dawei Han

Arthrosc Tech· July 2025

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Flow Cytometry-Based Rapid Assay for Antigen Specific Antibody Relative Affinity in SRBC-Immunized Mouse Models.
Chunli Sun, Yuan Jiang, Shujun Liu, Qilin He, Chengyao Han, Yan Zhang, Huihui Zhang

Int J Mol Sci· April 2025

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Efficacy and safety of finotonlimab plus docetaxel docetaxel in previously treated advanced squamous cell non-small-cell lung cancer: a randomized, double-blinded, phase III trial.
Baohui Han, Lin Wu, Runxiang Yang, Hongbo Wu, Wei Li, Mingjuan Zhang, Yanming Zhang, Chang Liu

Transl Lung Cancer Res· April 2025

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Engineering a photoactivatable A-to-I RNA base editor for gene therapy in vivo.
Huiying Li, Yuhao Qiu, Bowen Song, Xinyi Quan, Dan Zhang, Honghui Han, Xueli Zhang

Nat Biotechnol· March 2025

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EXPERT expands prime editing efficiency and range of large fragment edits.
Youcai Xiong, Yinyu Su, Ruigao He, Xiaosong Han, Sheng Li, Jifeng Zhang

Nat Commun· February 2025

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EccDNA atlas in male mice reveals features protecting genes against transcription-induced eccDNA formation.
Xue Liang, Gerard Arrey, Yating Qin, Lucía Álvarez-González, Judith Mary Hariprakash, Peng Han, Hanbo Li

Nat Commun· February 2025

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A Systematic Method to Detect Next-Generation Sequencing-Based Microsatellite Instability in Plasma Cell-Free DNA: plasmaMSI.
Fengchang Huang, Lili Zhao, Hongyu Xie, Tiancheng Han, Jian Huang

J Mol Diagn· January 2025

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Selective degradation of multimeric proteins by TRIM21-based molecular glue and PROTAC degraders.
Panrui Lu, Yalong Cheng, Lei Xue, Xintong Ren, Xilong Xu, Shan Sun, Ting Han

Cell· December 2024

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Arthroscopic Extensor Carpi Radialis Brevis Tenotomy Under Local Anesthesia for Refractory Lateral Epicondylitis.
Hanlong Xin, Li Ying, Qingguo Zhang, Dawei Han, Shuqiong Ge

Arthrosc Tech· December 2024

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BIRC5 upregulation enhances DNMT3A-mutant T-ALL cell survival and pathogenesis.
Wangisa Dunuwille, William C Wilson, Hassan Bjeije, Nancy Issa, Wentao Han

Blood Neoplasia· December 2024

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