Publications by authors named "Lance Munn"

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Efficient calculation of fluid transport in porous media with moving boundaries.
Huabing Li, Wenjie Lu, Badr Kaoui, James W Baish, Lance L Munn

bioRxiv· December 2025

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Physiologically based pharmacokinetic model for CAR-T cell delivery and efficacy in solid tumors.
Andreas G Hadjigeorgiou, Lance L Munn, Triantafyllos Stylianopoulos, Rakesh K Jain

Proc Natl Acad Sci U S A· November 2025

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A Hybrid Multiscale Model for Predicting CAR-T Therapy Outcomes in Solid Tumors.
Mohammad R Nikmaneshi, Lance L Munn

bioRxiv· November 2025

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Optimizing Cancer Vaccinations Using a Physiologically Based Pharmacokinetic (PBPK) Model.
Mohammad R Nikmaneshi, Timothy P Padera, Lance L Munn

bioRxiv· November 2025

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Probing the physical hallmarks of cancer.
Hadi T Nia, Lance L Munn, Rakesh K Jain

Nat Methods· September 2025

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Lymph node contraction links sex-biased naive CD8 T cell decline to compromised antigen recognition.
Lutz Menzel, Maria Zschummel, Meghan J O'Melia, Mårten Sandstedt, Hengbo Zhou, Lance L Munn

bioRxiv· September 2025

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Wnt inhibition alleviates resistance to anti-PD1 therapy and improves antitumor immunity in glioblastoma.
Shanmugarajan Krishnan, Somin Lee, Zohreh Amoozgar, Sonu Subudhi, Ashwin Srinivasan Kumar, Lance L Munn

Proc Natl Acad Sci U S A· September 2025

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Overcoming impaired antigen presentation in tumor draining lymph nodes facilitates immunotherapy.
Meghan J O'Melia, Lutz Menzel, Pin-Ji Lei, Hengbo Zhou, Neian Contreras-Alvarado, Lance L Munn

bioRxiv· September 2025

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The anti-virus T cell response dominates the anti-cancer response in oncolytic virus therapy.
Meghan J O'Melia, Kailan Sierra-Davidson, Miranda A Robert, Lutz Menzel, Lingshan Liu, Lance L Munn

bioRxiv· September 2025

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Mathematical Modeling and Association Analysis Decipher the Impact of the Gut Microbiome on Cancer Immunotherapy.
Andreas G Hadjigeorgiou, Constantinos Harkos, Aditya K Mishra, Golnaz Morad, Sarah B Johnson, Lance L Munn

Cancer Res· August 2025

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Solid Stress Estimations via Intraoperative 3D Navigation in Patients with Brain Tumors.
Hadi T Nia, Meenal Datta, Ashwin S Kumar, Saeed Siri, Gino B Ferraro, Lance L Munn

Clin Cancer Res· August 2025

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Physiologically-based pharmacokinetic model for CAR-T cells delivery and efficacy in solid tumors.
Andreas G Hadjigeorgiou, Lance L Munn, Triantafyllos Stylianopoulos, Rakesh K Jain

bioRxiv· August 2025

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Challenges and opportunities for the next generation of computational tumor models.
Lance L Munn, Rakesh K Jain

PLoS Biol· July 2025

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The cellular dance that splits vessels.
Lance L Munn

Proc Natl Acad Sci U S A· June 2025

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Biomarkers of mRNA vaccine efficacy derived from mechanistic modeling of tumor-immune interactions.
Chrysovalantis Voutouri, Lance L Munn, Triantafyllos Stylianopoulos, Rakesh K Jain

PLoS Comput Biol· June 2025

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Aging-induced changes in lymphatic muscle cell transcriptomes are associated with reduced pumping of peripheral collecting lymphatic vessels in mice.
Pin-Ji Lei, Katarina J Ruscic, Kangsan Roh, Johanna J Rajotte, Meghan J O'Melia, Lance L Munn

Dev Cell· April 2025

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Mechanics of Lymphatic Pumping and Lymphatic Function.
Mohammad S Razavi, Lance L Munn, Timothy P Padera

Cold Spring Harb Perspect Med· March 2025

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A multiresolution approach with method-informed statistical analysis for quantifying lymphatic pumping dynamics.
Mohammad S Razavi, Katarina J Ruscic, Elizabeth G Korn, Marla Marquez, Timothy T Houle, Lance L Munn

Npj Imaging· January 2025

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Solid stress estimations via intraoperative 3D navigation in patients with brain tumors.
Hadi T Nia, Meenal Datta, Ashwin S Kumar, Saeed Siri, Gino B Ferraro, Lance L Munn

medRxiv· December 2024

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Compressive stresses in cancer: characterization and implications for tumour progression and treatment.
Julia A Linke, Lance L Munn, Rakesh K Jain

Nat Rev Cancer· November 2024

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AMBER: A Modular Model for Tumor Growth, Vasculature and Radiation Response.
Louis V Kunz, Jesús J Bosque, Mohammad Nikmaneshi, Ibrahim Chamseddine, Lance L Munn

Bull Math Biol· October 2024

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Fluid dynamics and leukocyte transit in the lymphatic system.
Huabing Li, Jingjing Zhang, Timothy P Padera, James W Baish, Lance L Munn

PNAS Nexus· June 2024

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Dynamic heterogeneity in COVID-19: Insights from a mathematical model.
Chrysovalantis Voutouri, C Corey Hardin, Vivek Naranbhai, Mohammad R Nikmaneshi, Melin J Khandekar, Lance L Munn

PLoS One· May 2024

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Experimental and theoretical model of microvascular network remodeling and blood flow redistribution following minimally invasive microvessel laser ablation.
Gabriel Gruionu, James Baish, Sean McMahon, David Blauvelt, Lucian G Gruionu, Lance L Munn

Sci Rep· April 2024

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A Multiresolution Approach with Method-Informed Statistical Analysis for Quantifying Lymphatic Pumping Dynamics.
Mohammad S Razavi, Katarina J Ruscic, Elizabeth G Korn, Marla Marquez, Timothy T Houle, Lance L Munn

bioRxiv· April 2024

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