Publications by authors named "Lars Ellgaard"

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Specialized insulin is used for chemical warfare by fish-hunting cone snails.
Helena Safavi-Hemami, Joanna Gajewiak, Santhosh Karanth, Samuel D Robinson, Beatrix Ueberheide, Adam D Douglass, Amnon Schlegel, Julita S Imperial, Maren Watkins, Pradip K Bandyopadhyay

February 2015

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Structural similarities reveal an expansive conotoxin family with a two-finger toxin fold.
Muhammad Saad Khilji, Celeste M Hackney, Thomas L Koch, Arik J Hone, Aymeric Rogalski, Lars Ellgaard

Protein Sci· November 2025

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Conkazal-M1 from the MKAVA family of conotoxins - a dual-function protease inhibitor and neuroactive peptide.
Celeste M Hackney, Thomas Lund Koch, Nicklas Lund Ryding, Aymeric Rogalski, Kevin Chase, Lars Ellgaard

bioRxiv· November 2025

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Structural similarities reveal an expansive conotoxin family with a two-finger toxin fold.
Muhammad Saad Khilji, Celeste M Hackney, Thomas L Koch, Arik J Hone, Aymeric Rogalski, Lars Ellgaard

bioRxiv· July 2025

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A single-chain variable fragment selected against a conformational epitope of a recombinantly produced snake toxin using phage display.
Charlotte Rimbault, Pelle D Knudsen, Anna Damsbo, Kim Boddum, Hanif Ali, Lars Ellgaard

N Biotechnol· September 2023

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High-resolution crystal structure of the Mu8.1 conotoxin from Conus mucronatus.
Emilie Müller, Celeste Menuet Hackney, Lars Ellgaard, Jens Preben Morth

Acta Crystallogr F Struct Biol Commun· September 2023

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A previously unrecognized superfamily of macro-conotoxins includes an inhibitor of the sensory neuron calcium channel Cav2.3.
Celeste M Hackney, Paula Flórez Salcedo, Emilie Mueller, Thomas Lund Koch, Lau D Kjelgaard, Lars Ellgaard

PLoS Biol· August 2023

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Modern venomics-Current insights, novel methods, and future perspectives in biological and applied animal venom research.
Bjoern M von Reumont, Gregor Anderluh, Agostinho Antunes, Naira Ayvazyan, Dimitris Beis, Lars Ellgaard

Gigascience· May 2022

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Production of an Active, Human Membrane Protein in : Full-Length FICD.
Minttu S Virolainen, Cecilie L Søltoft, Per A Pedersen, Lars Ellgaard

Int J Mol Sci· February 2022

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Strategies for Heterologous Expression, Synthesis, and Purification of Animal Venom Toxins.
Esperanza Rivera-de-Torre, Charlotte Rimbault, Timothy P Jenkins, Christoffer V Sørensen, Anna Damsbo, Lars Ellgaard

Front Bioeng Biotechnol· January 2022

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DisCoTune: versatile auxiliary plasmids for the production of disulphide-containing proteins and peptides in the E. coli T7 system.
Andreas B Bertelsen, Celeste Menuet Hackney, Carolyn N Bayer, Lau D Kjelgaard, Maja Rennig, Lars Ellgaard

Microb Biotechnol· November 2021

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Curses or Cures: A Review of the Numerous Benefits Versus the Biosecurity Concerns of Conotoxin Research.
Walden E Bjørn-Yoshimoto, Iris Bea L Ramiro, Mark Yandell, J Michael McIntosh, Baldomero M Olivera, Lars Ellgaard

Biomedicines· July 2020

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Cellular functions and molecular mechanisms of non-lysine ubiquitination.
Amie J McClellan, Sophie Heiden Laugesen, Lars Ellgaard

Open Biol· September 2019

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The three-dimensional structure of an H-superfamily conotoxin reveals a granulin fold arising from a common ICK cysteine framework.
Lau D Nielsen, Mads M Foged, Anastasia Albert, Andreas B Bertelsen, Cecilie L Søltoft, Lars Ellgaard

J Biol Chem· May 2019

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Ero1-Mediated Reoxidation of Protein Disulfide Isomerase Accelerates the Folding of Cone Snail Toxins.
Henrik O'Brien, Shingo Kanemura, Masaki Okumura, Robert P Baskin, Pradip K Bandyopadhyay, Lars Ellgaard

Int J Mol Sci· October 2018

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How Are Proteins Reduced in the Endoplasmic Reticulum?
Lars Ellgaard, Carolyn S Sevier, Neil J Bulleid

Trends Biochem Sci· January 2018

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Co- and Post-Translational Protein Folding in the ER.
Lars Ellgaard, Nicholas McCaul, Anna Chatsisvili, Ineke Braakman

Traffic· June 2016

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Genetic dissection of mammalian ERAD through comparative haploid and CRISPR forward genetic screens.
Richard T Timms, Sam A Menzies, Iva A Tchasovnikarova, Lea C Christensen, James C Williamson, Lars Ellgaard

Nat Commun· June 2016

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Rapid expansion of the protein disulfide isomerase gene family facilitates the folding of venom peptides.
Helena Safavi-Hemami, Qing Li, Ronneshia L Jackson, Albert S Song, Wouter Boomsma, Lars Ellgaard

Proc Natl Acad Sci U S A· March 2016

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Bioinformatics analysis identifies several intrinsically disordered human E3 ubiquitin-protein ligases.
Wouter Boomsma, Sofie V Nielsen, Kresten Lindorff-Larsen, Rasmus Hartmann-Petersen, Lars Ellgaard

PeerJ· March 2016

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The selenium metabolite methylselenol regulates the expression of ligands that trigger immune activation through the lymphocyte receptor NKG2D.
Michael Hagemann-Jensen, Franziska Uhlenbrock, Stephanie Kehlet, Lars Andresen, Charlotte Gabel-Jensen, Lars Ellgaard

J Biol Chem· November 2014

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GPx8 peroxidase prevents leakage of H2O2 from the endoplasmic reticulum.
Thomas Ramming, Henning G Hansen, Kazuhiro Nagata, Lars Ellgaard, Christian Appenzeller-Herzog

Free Radic Biol Med· May 2014

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Biochemical evidence that regulation of Ero1β activity in human cells does not involve the isoform-specific cysteine 262.
Henning G Hansen, Cecilie L Søltoft, Jonas D Schmidt, Julia Birk, Christian Appenzeller-Herzog, Lars Ellgaard

Biosci Rep· April 2014

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HUWE1 and TRIP12 collaborate in degradation of ubiquitin-fusion proteins and misframed ubiquitin.
Esben G Poulsen, Cornelia Steinhauer, Michael Lees, Anne-Marie Lauridsen, Lars Ellgaard

PLoS One· May 2013

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Hyperactivity of the Ero1α oxidase elicits endoplasmic reticulum stress but no broad antioxidant response.
Henning Gram Hansen, Jonas Damgård Schmidt, Cecilie Lützen Søltoft, Thomas Ramming, Henrik Marcus Geertz-Hansen, Lars Ellgaard

J Biol Chem· November 2012

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