Publications by authors named "Laura Pascal"

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Estrogen regulation in the prostate underlies racial disparity in men with benign prostatic hyperplasia.
Teresa T Liu, Laura E Pascal, Emily A Ricke, Ana Lucila Bautista-Ruiz, Justin Townsend

J Pathol· November 2025

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ZC3H4, a novel regulator of mitochondrial complex I, impacts prostate stromal cell senescence, attachment, adhesion and anoikis resistance.
Teresa T Liu, Mia J Carrarini, Livianna K Myklebust, Kegan O Skalitzky, Nathalie El-Khoury, Laura E Pascal

Cell Death Dis· October 2025

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Regulation of glucocorticoid receptor nuclear localization in prostate cancer cells.
Guang Chen, Shidong Lv, Laura E Pascal, Zhou Wang

J Pharmacol Exp Ther· May 2025

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Dietary methionine restriction started late in life promotes healthy aging in a sex-specific manner.
Ulalume Hernández-Arciga, Ceda Stamenkovic, Shweta Yadav, Chiara Nicoletti, Wafaa N Albalawy, Laura E Pascal

Sci Adv· April 2025

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Benign prostatic hyperplasia nodules in patients treated with celecoxib and/or finasteride have reduced levels of NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, a mitochondrial protein essential for efficient function of the electron transport chain.
Teresa T Liu, Taro Igarashi, Nathalie El-Khoury, Nnamdi Ihejirika, Kelsey Paxton, Laura E Pascal

Prostate· October 2024

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Effects of oral administration of nonselective Trk inhibitor on bladder overactivity in rodent models of prostatic inflammation.
Taro Igarashi, Shinsuke Mizoguchi, Kanako Matsuoka, Tadanobu Kamijo, Shota Kawano, Laura E Pascal

Prostate· August 2024

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Aging-Related Mitochondrial Dysfunction Is Associated With Fibrosis in Benign Prostatic Hyperplasia.
Alexis E Adrian, Teresa T Liu, Laura E Pascal, Scott R Bauer, Donald B DeFranco

J Gerontol A Biol Sci Med Sci· June 2024

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Age-Dependent Effects of Voluntary Wheel Running Exercise on Voiding Behavior and Potential Age-Related Molecular Mechanisms in Mice.
Teresa T Liu, Laura E Pascal, Scott R Bauer, Hannah N Miles, Jules B Panksepp

J Gerontol A Biol Sci Med Sci· June 2024

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Genetic alterations in CREBRF influence prostate cancer survival and impact prostate tissue homeostasis in mice.
Laura E Pascal, Krystle A Frahm, Kegan O Skalitzky, Donald B DeFranco, Lora H Rigatti

Am J Clin Exp Urol· February 2023

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Integrated analysis reveals FOXA1 and Ku70/Ku80 as targets of ivermectin in prostate cancer.
Shidong Lv, Zeyu Wu, Mayao Luo, Yifan Zhang, Jianqiang Zhang, Laura E Pascal

Cell Death Dis· September 2022

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Increased COX-1 expression in benign prostate epithelial cells is triggered by mitochondrial dysfunction.
Chandler N Hudson, Kai He, Laura E Pascal, Teresa Liu, Livianna K Myklebust

Am J Clin Exp Urol· August 2022

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(+)-JJ-74-138 is a Novel Noncompetitive Androgen Receptor Antagonist.
Ryan N Cole, Wei Chen, Laura E Pascal, Joel B Nelson, Peter Wipf

Mol Cancer Ther· April 2022

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E-cadherin deficiency promotes prostate macrophage inflammation and bladder overactivity in aged male mice.
Laura E Pascal, Taro Igarashi, Shinsuke Mizoguchi, Wei Chen, Lora H Rigatti

Aging (Albany NY)· March 2022

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The classical and updated models of androgen receptor nucleocytoplasmic trafficking.
Ryan Cole, Laura E Pascal, Zhou Wang

Am J Clin Exp Urol· August 2021

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Abnormal expression of Rab27B in prostatic epithelial cells of benign prostatic hyperplasia alters intercellular communication.
Yu Dai, Bo Ai, Ying Liu, Laura E Pascal, Zhou Wang

Int J Biochem Cell Biol· February 2021

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Regulation and targeting of androgen receptor nuclear localization in castration-resistant prostate cancer.
Shidong Lv, Qiong Song, Guang Chen, Erdong Cheng, Wei Chen, Laura E Pascal

J Clin Invest· February 2021

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Claudin-1 down-regulation in the prostate is associated with aging and increased infiltration of inflammatory cells in BPH.
Laura E Pascal, Rajiv Dhir, Goundappa K Balasubramani, Wei Chen, Chandler N Hudson

Am J Clin Exp Urol· February 2021

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E-cadherin expression is inversely correlated with aging and inflammation in the prostate.
Laura E Pascal, Rajiv Dhir, Goundappa K Balasubramani, Wei Chen, Chandler N Hudson

Am J Clin Exp Urol· February 2021

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Prostate-Specific Deletion of Cdh1 Induces Murine Prostatic Inflammation and Bladder Overactivity.
Laura E Pascal, Shinsuke Mizoguchi, Wei Chen, Lora H Rigatti, Taro Igarashi

Endocrinology· January 2021

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Differential impact of paired patient-derived BPH and normal adjacent stromal cells on benign prostatic epithelial cell growth in 3D culture.
Wei Chen, Laura E Pascal, Ke Wang, Rajiv Dhir, Alexa M Sims

Prostate· October 2020

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Tight junction protein claudin-1 is downregulated by TGF-β1 via MEK signaling in benign prostatic epithelial cells.
Ke Wang, Laura E Pascal, Feng Li, Wei Chen, Rajiv Dhir

Prostate· October 2020

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ELL2 Is Required for the Growth and Survival of AR-Negative Prostate Cancer Cells.
Zhi Wang, Laura E Pascal, Uma R Chandran, Srilakshmi Chaparala, Shidong Lv

Cancer Manag Res· June 2020

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SIRPB1 promotes prostate cancer cell proliferation via Akt activation.
Qiong Song, Siyuan Qin, Laura E Pascal, Chunlin Zou, Wenchu Wang

Prostate· March 2020

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Transforming growth factor beta 1 impairs benign prostatic luminal epithelial cell monolayer barrier function.
Feng Li, Laura E Pascal, Ke Wang, Yibin Zhou, Goundappa K Balasubramani

Am J Clin Exp Urol· February 2020

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EAF2 loss induces prostatic intraepithelial neoplasia from luminal epithelial cells in mice.
Laura E Pascal, Lora H Rigatti, Junkui Ai, Aiyuan Zhang, Jianhua Zhou

Am J Clin Exp Urol· February 2020

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