Publications by authors named "Lee Spate"

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Conceptus estrogen and prostaglandins provide the maternal recognition of pregnancy signal to prevent luteolysis during early pregnancy in the pig†.
Riley M Sullivan, Caroline G Lucas, Mariana Sponchiado, Emily K Eitel, Lee D Spate

Biol Reprod· October 2024

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Fetal bone engraftment reconstitutes the immune system in pigs with severe combined immunodeficiency.
Kaylynn Monarch, Junchul Yoon, Kyungjun Uh, Emily Reese, Diana Canaveral Restrepo, Lee D Spate

Lab Anim (NY)· October 2024

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Impaired Skeletal Development by Disruption of Presenilin-1 in Pigs and Generation of Novel Pig Models for Alzheimer's Disease.
Kyungjun Uh, Kaylynn Monarch, Emily D Reese, Katherine Rodriguez, Junchul Yoon, Lee D Spate

J Alzheimers Dis· September 2024

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Oocyte recovery after overnight ovary transport provides an alternative source of cumulus oocyte complexes that are competent to produce live piglets.
Lee D Spate, Jie Yin, Lauren Sammel, Randall S Prather, Bethany K Redel

Reprod Domest Anim· December 2023

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FGF2, LIF, and IGF1 (FLI) supplementation during human in vitro maturation enhances markers of gamete competence.
Farners Amargant, Luhan T Zhou, Ye Yuan, Asrafun Nahar, Rebecca L Krisher, Lee D Spate

Hum Reprod· October 2023

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Inactivation of growth differentiation factor 9 blocks folliculogenesis in pigs†.
Paula R Chen, Kyungjun Uh, Kaylynn Monarch, Lee D Spate, Emily D Reese

Biol Reprod· April 2023

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Profiling development of abdominal organs in the pig.
George C Gabriel, William A Devine, Bethany K Redel, Kristin M Whitworth, Melissa Samuel, Lee D Spate

Sci Rep· September 2022

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Disruption of anthrax toxin receptor 1 in pigs leads to a rare disease phenotype and protection from senecavirus A infection.
Paula R Chen, Raymond R R Rowland, Ana M Stoian, Vlad Petrovan, Maureen Sheahan, Lee D Spate

Sci Rep· March 2022

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Conceptus interferon gamma is essential for establishment of pregnancy in the pig†.
Destiny N Johns, Caroline G Lucas, Caroline A Pfeiffer, Paula R Chen, Ashley E Meyer, Lee D Spate

Biol Reprod· December 2021

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Disrupting porcine glutaminase does not block preimplantation development and elongation nor decrease mTORC1 activation in conceptuses†.
Paula R Chen, Caroline G Lucas, Raissa F Cecil, Caroline A Pfeiffer, Melissa A Fudge, Lee D Spate

Biol Reprod· November 2021

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Challenges and Considerations during In Vitro Production of Porcine Embryos.
Paula R Chen, Bethany K Redel, Karl C Kerns, Lee D Spate, Randall S Prather

Cells· October 2021

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Neither gonadotropin nor cumulus cell expansion is needed for the maturation of competent porcine oocytes in vitro†.
Bethany K Redel, Lee D Spate, Ye Yuan, Clifton N Murphy, R Michael Roberts

Biol Reprod· August 2021

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Improved cryopreservation of in vitro produced bovine embryos using FGF2, LIF, and IGF1.
Katy S Stoecklein, M Sofia Ortega, Lee D Spate, Clifton N Murphy, Randall S Prather

PLoS One· July 2021

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Glutaminolysis is involved in the activation of mTORC1 in in vitro-produced porcine embryos.
Paula R Chen, Caroline G Lucas, Lee D Spate, Randall S Prather

Mol Reprod Dev· July 2021

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Cardiovascular Development and Congenital Heart Disease Modeling in the Pig.
George C Gabriel, William Devine, Bethany K Redel, Kristin M Whitworth, Melissa Samuel, Lee D Spate

J Am Heart Assoc· July 2021

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Lack of airway submucosal glands impairs respiratory host defenses.
Lynda S Ostedgaard, Margaret P Price, Kristin M Whitworth, Mahmoud H Abou Alaiwa, Anthony J Fischer, Lee D Spate

Elife· October 2020

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A porcine model of phenylketonuria generated by CRISPR/Cas9 genome editing.
Erik A Koppes, Bethany K Redel, Marie A Johnson, Kristen J Skvorak, Lina Ghaloul-Gonzalez, Lee D Spate

JCI Insight· October 2020

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Removal of hypotaurine from porcine embryo culture medium does not impair development of in vitro-fertilized or somatic cell nuclear transfer-derived embryos at low oxygen tension.
Paula R Chen, Lee D Spate, Eric C Leffeler, Joshua A Benne, Raissa F Cecil

Mol Reprod Dev· July 2020

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Chemical simulation of hypoxia in donor cells improves development of somatic cell nuclear transfer-derived embryos and increases abundance of transcripts related to glycolysis.
Raissa F Cecil, Paula R Chen, Joshua A Benne, Taylor K Hord, Lee D Spate

Mol Reprod Dev· July 2020

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In Vitro Maturation, Fertilization, and Culture of Pig Oocytes and Embryos.
Bethany K Redel, Lee D Spate, Randall S Prather

Methods Mol Biol· March 2020

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Ablation of conceptus PTGS2 expression does not alter early conceptus development and establishment of pregnancy in the pig†.
Caroline A Pfeiffer, Ashley E Meyer, Kelsey E Brooks, Paula R Chen, Jessica Milano-Foster, Lee D Spate

Biol Reprod· February 2020

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New perspective on conceptus estrogens in maternal recognition and pregnancy establishment in the pig†.
Ashley E Meyer, Caroline A Pfeiffer, Kelsey E Brooks, Lee D Spate, Joshua A Benne

Biol Reprod· July 2019

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Improvement of in vitro and early in utero porcine clone development after somatic donor cells are cultured under hypoxia.
Bethany R Mordhorst, Joshua A Benne, Raissa F Cecil, Kristin M Whitworth, Melissa S Samuel, Lee D Spate

Mol Reprod Dev· May 2019

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Glutamine supplementation enhances development of in vitro-produced porcine embryos and increases leucine consumption from the medium.
Paula R Chen, Bethany K Redel, Lee D Spate, Tieming Ji, Shirley Rojas Salazar

Biol Reprod· November 2018

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Single step production of Cas9 mRNA for zygote injection.
Bethany K Redel, Benjamin P Beaton, Lee D Spate, Joshua A Benne, Stephanie L Murphy, Anna M Spate

Biotechniques· March 2018

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