Publications by authors named "Leeming Chuang"

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Risk of major adverse cardiovascular events and all-cause mortality in type 2 diabetic patients receiving insulin versus non-insulin treatment intensification.
Yu-Jie Lin, Peter Pin-Sung Liu, Hui-Kai Huang, Hwan-Wun Liu, Ching-Hui Loh, Lee-Ming Chuang

Sci Rep· August 2025

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Multi-ancestry polygenic risk scores for the prediction of type 2 diabetes and complications in diverse ancestries.
Alicia Huerta-Chagoya, Joohyun Kim, Ravi Mandla, Yingchang Lu, Ken Suzuki, Lee-Ming Chuang

medRxiv· July 2025

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Identification of PTGR2 inhibitors as a new therapeutic strategy for diabetes and obesity.
Yi-Cheng Chang, Meng-Lun Hsieh, Hsiao-Lin Lee, Siow-Wey Hee, Chi-Fon Chang, Lee-Ming Chuang

EMBO Mol Med· May 2025

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Author Correction: Identification of PTGR2 inhibitors as a new therapeutic strategy for diabetes and obesity.
Yi-Cheng Chang, Meng-Lun Hsieh, Hsiao-Lin Lee, Siow-Wey Hee, Chi-Fon Chang, Lee-Ming Chuang

EMBO Mol Med· May 2025

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Whole genome sequencing analysis of body mass index identifies novel African ancestry-specific risk allele.
Xinruo Zhang, Jennifer A Brody, Mariaelisa Graff, Heather M Highland, Nathalie Chami, Lee-Ming Chuang

Nat Commun· April 2025

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Positive correlation of ANGPTL8 expression in human visceral adipose tissue with body mass index.
Shiau-Mei Chen, Tse-Ying Huang, Wei-Jei Lee, Lee-Ming Chuang, Tien-Jyun Chang

J Formos Med Assoc· August 2024

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Urinary Post-Translationally Modified Fetuin-A Protein Is Associated with Increased Risk of Graft Failure in Kidney Transplant Recipients.
Firas F Alkaff, Daan Kremer, Charlotte A Te Velde-Keyzer, Jacob van den Born, Stefan P Berger, Lee-Ming Chuang

Am J Nephrol· April 2024

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Recent advances in the treatment of type 2 diabetes mellitus using new drug therapies.
Keong Chong, Jack Keng-Jui Chang, Lee-Ming Chuang

Kaohsiung J Med Sci· March 2024

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Reply for comments on "Roux-en-Y and One-anastomosis Gastric Bypass Surgery Are Superior to Sleeve Gastrectomy in Lowering Glucose and Cholesterol Levels Independent of Weight Loss: a Propensity-Score Weighting Analysis".
Yi-Cheng Chang, Chih-Neng Hsu, Keong Chong, Chin-Feng Hsuan, Lee-Ming Chuang

Obes Surg· March 2024

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Genetic drivers of heterogeneity in type 2 diabetes pathophysiology.
Ken Suzuki, Konstantinos Hatzikotoulas, Lorraine Southam, Henry J Taylor, Xianyong Yin, Lee-Ming Chuang

Nature· March 2024

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Diabetes self-management education on the sustainability of metabolic control in type 2 diabetes patients: Diabetes share care program in Taiwan.
Ying-Chuen Lai, Yi-Shuan Chen, Yi-Der Jiang, Chiou-Shiang Wang, I-Ching Wang, Lee-Ming Chuang

J Formos Med Assoc· February 2024

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Urinary Fetuin-A Fragments Predict Progressive Estimated Glomerular Filtration Rate Decline in Two Independent Type 2 Diabetes Cohorts of Different Ethnicities.
Gwo-Tsann Chuang, Daan Kremer, Chi-Hsuan Huang, Firas F Alkaff, Chih-Hung Lin, Lee-Ming Chuang

Am J Nephrol· February 2024

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Residual risk of cardiovascular complications in statin-using patients with type 2 diabetes: the Taiwan Diabetes Registry Study.
Chin-Sung Kuo, Nai-Rong Kuo, Yun-Kai Yeh, Yau-Jiunn Lee, Lee-Ming Chuang

Lipids Health Dis· January 2024

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Roux-en-Y and One-Anastomosis Gastric Bypass Surgery Are Superior to Sleeve Gastrectomy in Lowering Glucose and Cholesterol Levels Independent of Weight Loss: a Propensity-Score Weighting Analysis.
Yi-Cheng Chang, Chih-Neng Hsu, Keong Chong, Po-Jen Yang, Kong-Han Ser, Gwo-Tsann Chuang, Lee-Ming Chuang

Obes Surg· October 2023

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15-keto-PGE alleviates nonalcoholic steatohepatitis through its covalent modification of NF-κB factors.
Siow-Wey Hee, Yi-Cheng Chang, Lynn Su, Ing-Jung Chen, Yung-Ming Jeng, Lee-Ming Chuang

iScience· October 2023

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A common East-Asian ALDH2 mutation causes metabolic disorders and the therapeutic effect of ALDH2 activators.
Yi-Cheng Chang, Hsiao-Lin Lee, Wenjin Yang, Meng-Lun Hsieh, Cai-Cin Liu, Hsiao-Li Chuang, Lee-Ming Chuang

Nat Commun· September 2023

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WHOLE GENOME SEQUENCING ANALYSIS OF BODY MASS INDEX IDENTIFIES NOVEL AFRICAN ANCESTRY-SPECIFIC RISK ALLELE.
Xinruo Zhang, Jennifer A Brody, Mariaelisa Graff, Heather M Highland, Nathalie Chami, Lee-Ming Chuang

medRxiv· August 2023

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Genome-wide association study and functional characterization identifies candidate genes for insulin-stimulated glucose uptake.
Alice Williamson, Dougall M Norris, Xianyong Yin, K Alaine Broadaway, Anne H Moxley, Lee-Ming Chuang

Nat Genet· June 2023

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Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications.
Ken Suzuki, Konstantinos Hatzikotoulas, Lorraine Southam, Henry J Taylor, Xianyong Yin, Lee-Ming Chuang

medRxiv· March 2023

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GSK3α phosphorylates dynamin-2 to promote GLUT4 endocytosis in muscle cells.
Jessica Laiman, Yen-Jung Hsu, Julie Loh, Wei-Chun Tang, Mei-Chun Chuang, Lee-Ming Chuang

J Cell Biol· February 2023

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Multi-ancestry transcriptome-wide association analyses yield insights into tobacco use biology and drug repurposing.
Fang Chen, Xingyan Wang, Seon-Kyeong Jang, Bryan C Quach, J Dylan Weissenkampen, Lee-Ming Chuang

Nat Genet· February 2023

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A randomized trial on the effect of transcutaneous electrical nerve stimulator on glycemic control in patients with type 2 diabetes.
Jin-Ying Lu, Horng-Yih Ou, Chung-Ze Wu, Chwen-Yi Yang, Ju-Ying Jiang, Lee-Ming Chuang

Sci Rep· February 2023

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ER ribosomal-binding protein 1 regulates blood pressure and potassium homeostasis by modulating intracellular renin trafficking.
Chu-Hsuan Chiu, Chin-Feng Hsuan, Shih-Hua Lin, Yi-Jen Hung, Chii-Min Hwu, Gwo-Tsann Chuang, Lee-Ming Chuang

J Biomed Sci· February 2023

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Emerging Therapy for Diabetic Cardiomyopathy: From Molecular Mechanism to Clinical Practice.
Chin-Feng Hsuan, Sean I F Teng, Chih-Neng Hsu, Daniel Liao, Allen Jiun-Wei Chang, Lee-Ming Chuang

Biomedicines· February 2023

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Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis.
Stavroula Kanoni, Sarah E Graham, Yuxuan Wang, Ida Surakka, Shweta Ramdas, Lee-Ming Chuang

Genome Biol· December 2022

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