Publications by authors named "Leif Groop"

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1-Hour Post-OGTT Glucose Improves the Early Prediction of Type 2 Diabetes by Clinical and Metabolic Markers.
Gopal Peddinti, Michael Bergman, Tiinamaija Tuomi, Leif Groop

J Clin Endocrinol Metab· April 2019

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Relationship between testosterone levels, insulin sensitivity, and mitochondrial function in men.
Nelly Pitteloud, Vamsi K Mootha, Andrew A Dwyer, Megan Hardin, Hang Lee, Karl-Fredrik Eriksson, Devjit Tripathy, Maria Yialamas, Leif Groop, Dariush Elahi

July 2005

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GWAS of random glucose in 476,326 individuals provide insights into diabetes pathophysiology, complications and treatment stratification.
Vasiliki Lagou, Longda Jiang, Anna Ulrich, Liudmila Zudina, Karla Sofia Gutiérrez González, Leif Groop

Nat Genet· September 2023

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Genetic insights into resting heart rate and its role in cardiovascular disease.
Yordi J van de Vegte, Ruben N Eppinga, M Yldau van der Ende, Yanick P Hagemeijer, Yuvaraj Mahendran, Leif Groop

Nat Commun· August 2023

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Genome-wide association study and functional characterization identifies candidate genes for insulin-stimulated glucose uptake.
Alice Williamson, Dougall M Norris, Xianyong Yin, K Alaine Broadaway, Anne H Moxley, Leif Groop

Nat Genet· June 2023

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Identification of biomarkers for glycaemic deterioration in type 2 diabetes.
Roderick C Slieker, Louise A Donnelly, Elina Akalestou, Livia Lopez-Noriega, Rana Melhem, Leif Groop

Nat Commun· May 2023

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Genome-wide mRNA profiling in urinary extracellular vesicles reveals stress gene signature for diabetic kidney disease.
Om Prakash Dwivedi, Karina Barreiro, Annemari Käräjämäki, Erkka Valo, Anil K Giri, Per-Henrik Groop, Leif Groop

iScience· May 2023

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Smoking, use of smokeless tobacco, HLA genotypes and incidence of latent autoimmune diabetes in adults.
Jessica Edstorp, Yuxia Wei, Emma Ahlqvist, Lars Alfredsson, Valdemar Grill, Leif Groop

Diabetologia· January 2023

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The type 1 diabetes gene TYK2 regulates β-cell development and its responses to interferon-α.
Vikash Chandra, Hazem Ibrahim, Clémentine Halliez, Rashmi B Prasad, Federica Vecchio, Leif Groop

Nat Commun· October 2022

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Desmoglein-2 is important for islet function and β-cell survival.
Kay K Myo Min, Darling Rojas-Canales, Daniella Penko, Mark DeNichilo, Michaelia P Cockshell, Leif Groop

Cell Death Dis· October 2022

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Multi-ancestry genome-wide association study of gestational diabetes mellitus highlights genetic links with type 2 diabetes.
Natalia Pervjakova, Gunn-Helen Moen, Maria-Carolina Borges, Teresa Ferreira, James P Cook, Leif Groop

Hum Mol Genet· September 2022

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Genome-wide meta-analysis and omics integration identifies novel genes associated with diabetic kidney disease.
Niina Sandholm, Joanne B Cole, Viji Nair, Xin Sheng, Hongbo Liu, Leif Groop, Per-Henrik Groop

Diabetologia· September 2022

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Mechanistic Insights Into the Heterogeneity of Glucose Response Classes in Youths With Obesity: A Latent Class Trajectory Approach.
Domenico Tricò, Sarah McCollum, Stephanie Samuels, Nicola Santoro, Alfonso Galderisi, Leif Groop

Diabetes Care· August 2022

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Distribution and characteristics of newly-defined subgroups of type 2 diabetes in randomised clinical trials: Post hoc cluster assignment analysis of over 12,000 study participants.
Wolfgang Landgraf, Gregory Bigot, Sibylle Hess, Olof Asplund, Leif Groop

Diabetes Res Clin Pract· August 2022

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Islet Gene View-a tool to facilitate islet research.
Olof Asplund, Petter Storm, Vikash Chandra, Gad Hatem, Emilia Ottosson-Laakso, Leif Groop

Life Sci Alliance· August 2022

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Novel Subgroups of Type 2 Diabetes Display Different Epigenetic Patterns That Associate With Future Diabetic Complications.
Silja Schrader, Alexander Perfilyev, Emma Ahlqvist, Leif Groop, Allan Vaag

Diabetes Care· July 2022

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Obesity-associated Blunted Subcutaneous Adipose Tissue Blood Flow After Meal Improves After Bariatric Surgery.
Teemu Saari, Jukka Koffert, Henri Honka, Saila Kauhanen, Mueez U-Din, Leif Groop

J Clin Endocrinol Metab· June 2022

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Correction to: A multigenerational study on phenotypic consequences of the most common causal variant of HNF1A-MODY.
Jarno L T Kettunen, Elina Rantala, Om P Dwivedi, Bo Isomaa, Leena Sarelin, Leif C Groop

Diabetologia· May 2022

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Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation.
Anubha Mahajan, Cassandra N Spracklen, Weihua Zhang, Maggie C Y Ng, Lauren E Petty, Leif Groop

Nat Genet· May 2022

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A multigenerational study on phenotypic consequences of the most common causal variant of HNF1A-MODY.
Jarno L T Kettunen, Elina Rantala, Om P Dwivedi, Bo Isomaa, Leena Sarelin, Leif C Groop

Diabetologia· April 2022

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Mapping the Cord Blood Transcriptome of Pregnancies Affected by Early Maternal Anemia to Identify Signatures of Fetal Programming.
Gad Hatem, Line Hjort, Olof Asplund, Daniel T R Minja, Omari Abdul Msemo, Leif Groop

J Clin Endocrinol Metab· April 2022

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Two New Mutations in the CEL Gene Causing Diabetes and Hereditary Pancreatitis: How to Correctly Identify MODY8 Cases.
Khadija El Jellas, Petra Dušátková, Ingfrid S Haldorsen, Janne Molnes, Erling Tjora, Leif Groop

J Clin Endocrinol Metab· March 2022

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Data-driven subgroups of type 2 diabetes, metabolic response, and renal risk profile after bariatric surgery: a retrospective cohort study.
Violeta Raverdy, Ricardo V Cohen, Robert Caiazzo, Helene Verkindt, Tarissa Beatrice Zanata Petry, Leif Groop

Lancet Diabetes Endocrinol· March 2022

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Correction to: Subgroups of patients with young-onset type 2 diabetes in India reveal insulin deficiency as a major driver.
Rashmi B Prasad, Olof Asplund, Sharvari R Shukla, Rucha Wagh, Pooja Kunte, Leif Groop

Diabetologia· January 2022

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Rare coding variants in 35 genes associate with circulating lipid levels-A multi-ancestry analysis of 170,000 exomes.
George Hindy, Peter Dornbos, Mark D Chaffin, Dajiang J Liu, Minxian Wang, Leif C Groop

Am J Hum Genet· January 2022

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Epigenome-Wide Histone Acetylation Changes in Peripheral Blood Mononuclear Cells in Patients with Type 2 Diabetes and Atherosclerotic Disease.
Pradeep Bompada, Isabel Goncalves, Chuanyan Wu, Rui Gao, Jiangming Sun, Leif Groop

Biomedicines· December 2021

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Lipid-Associated Variants near ANGPTL3 and LPL Show Parent-of-Origin Specific Effects on Blood Lipid Levels and Obesity.
Anna Lessmark, Gad Hatem, Györgyi Kovacs, Marta Vitai, Emma Ahlqvist, Leif Groop

Genes (Basel)· December 2021

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