Publications by authors named "Leif Ostergaard"

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Perfusion magnetic resonance imaging: a comprehensive update on principles and techniques.
Geon-Ho Jahng, Ka-Loh Li, Leif Ostergaard, Fernando Calamante

November 2014

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Cortical Microvascular Pulsatility in the Aging Mouse Brain and the Confounding Effects of Anesthesia.
Mia Viuf Skøtt, Elizaveta Melnikova, Eugenio Gutiérrez, Vladimir Matchkov, Leif Østergaard

Adv Sci (Weinh)· November 2025

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Isoflurane anesthesia alters 31P magnetic resonance spectroscopy markers compared to awake mouse brain.
Saba Molhemi, Rasmus West Knopper, Christian Stald Skoven, Thomas Beck Lindhardt, Caroline Degel

PLoS One· November 2025

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Sex-Specific Cortical Brain Differences in Children at Familial High Risk for Schizophrenia or Bipolar Disorder.
Kathrine Skak Madsen, William F C Baaré, Enedino Hernandez-Torres, Kit Melissa Larsen, Adam Kaminski

Biol Psychiatry Cogn Neurosci Neuroimaging· August 2025

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Estimation of oxygen extraction fraction based on hemodynamic measurements using DSC-MRI.
Lasse Stensvig Madsen, Malene Kaasing Thomsen, Hugo Angleys, Irene Klærke Mikkelsen, David James Brooks

Imaging Neurosci (Camb)· May 2025

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Pericytes in the brain and heart: functional roles and response to ischaemia and reperfusion.
Turgay Dalkara, Leif Østergaard, Gerd Heusch, David Attwell

Cardiovasc Res· April 2025

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Cerebral proteome adaptations to amyloid angiopathy are prevented by carbonic anhydrase inhibitors.
Jasper Carlsen, Silvia Fossati, Leif Østergaard, Eugenio Gutiérrez-Jiménez, Johan Palmfeldt

Alzheimers Dement· April 2025

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A low-cost open-source 3D-printed mouse cradle suspension system for awake or anaesthetised H/P magnetic resonance spectroscopy.
Saba Molhemi, Leif Østergaard, Brian Hansen

HardwareX· March 2025

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Carbonic anhydrase inhibitors prevent presymptomatic capillary flow disturbances in a model of cerebral amyloidosis.
Eugenio Gutiérrez-Jiménez, Peter Mondrup Rasmussen, Irene Klærke Mikkelsen, Sreekanth Kura, Signe K Fruekilde

Alzheimers Dement· March 2025

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Brain Activation and Aberrant Effective Connectivity in the Mentalizing Network of Preadolescent Children at Familial High Risk of Schizophrenia or Bipolar Disorder.
Lotte Veddum, Vibeke Bliksted, Yuan Zhou, Anna Krogh Andreassen, Christina Bruun Knudsen

Biol Psychiatry Cogn Neurosci Neuroimaging· January 2025

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Carbonic anhydrase inhibitors prevent presymptomatic capillary flow disturbances in a model of cerebral amyloidosis.
Eugenio Gutiérrez-Jiménez, Peter Mondrup Rasmussen, Irene Klærke Mikkelsen, Sreekanth Kura, Signe K Fruekilde

bioRxiv· December 2024

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The effects of locus coeruleus ablation on mouse brain volume and microstructure evaluated by high-field MRI.
Rasmus West Knopper, Christian Stald Skoven, Simon Fristed Eskildsen, Leif Østergaard, Brian Hansen

Front Cell Neurosci· December 2024

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Differentiation of MS lesions through analysis of microvascular distribution.
Linda Sundvall, Irene Klærke Mikkelsen, Simon F Eskildsen, Mette Madsen Hjørringgaard, Mikkel Nygaard

Imaging Neurosci (Camb)· November 2024

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Blood-brain Barrier Permeability May Influence Vasopressor Effects in Anesthetized Patients With Brain Tumor: An Analysis of Magnetic Resonance Imaging Data.
Mads Rasmussen, Klaus U Koch, Ulrick S Espelund, Niwar Mohamad, Anders R Korshøj

J Neurosurg Anesthesiol· October 2024

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Cerebral microvascular changes in healthy carriers of the APOE-ɛ4 Alzheimer's disease risk gene.
Rasmus Aamand, Peter M Rasmussen, Katrine Schilling Andersen, Stine de Paoli, Eddie Weitzberg

PNAS Nexus· September 2024

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The Larmor frequency shift of a white matter magnetic microstructure model with multiple sources.
Anders Dyhr Sandgaard, Noam Shemesh, Leif Østergaard, Valerij G Kiselev, Sune Nørhøj Jespersen

NMR Biomed· August 2024

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Hypoparathyroidism: changes in brain structure, cognitive impairment, and reduced quality of life.
Tanja Sikjaer, Simon Fristed Eskildsen, Line Underbjerg, Leif Østergaard, Lars Rejnmark

J Bone Miner Res· August 2024

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Anesthesia-related brain microstructure modulations detected by diffusion magnetic resonance imaging.
Thomas Beck Lindhardt, Christian Stald Skoven, Luca Bordoni, Leif Østergaard, Zhifeng Liang

NMR Biomed· July 2024

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Exploring vascular contributions to cognitive impairment and dementia (ENIGMA): protocol for a prospective observational study.
Sigrid Breinholt Vestergaard, Andreas Gammelgaard Damsbo, Niels Lech Pedersen, Katrine Zachariassen, Kim Ryun Drasbek

BMC Neurol· April 2024

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Performance on complex memory tests is associated with β-amyloid in individuals at risk of developing Alzheimer's disease.
Pernille Louise Kjeldsen, Malene Flensborg Damholdt, Lasse Stensvig Madsen, Peter Henrik Nissen, Joel Fredrik Astrup Aanerud

J Neuropsychol· March 2024

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A semi-automatic method for extracting mitochondrial cristae characteristics from 3D focused ion beam scanning electron microscopy data.
Chenhao Wang, Leif Østergaard, Stine Hasselholt, Jon Sporring

Commun Biol· March 2024

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Capillary dysfunction in healthy elderly APOE ε4 carriers with raised brain Aβ deposition.
Lasse S Madsen, Pernille L Kjeldsen, Rola Ismail, Peter Parbo, Leif Østergaard

Alzheimers Dement· January 2024

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FDA-approved carbonic anhydrase inhibitors reduce amyloid β pathology and improve cognition, by ameliorating cerebrovascular health and glial fitness.
Elisa Canepa, Rebecca Parodi-Rullan, Rafael Vazquez-Torres, Begona Gamallo-Lana, Roberto Guzman-Hernandez

Alzheimers Dement· November 2023

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Deletion of aquaporin-4 improves capillary blood flow distribution in brain edema.
Luca Bordoni, Anna E Thoren, Eugenio Gutiérrez-Jiménez, Knut S Åbjørsbråten, Daniel M Bjørnstad

Glia· November 2023

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Locus coeruleus ablation in mice: protocol optimization, stereology and behavioral impact.
Nanna Bertin Markussen, Rasmus West Knopper, Stine Hasselholt, Christian Stald Skoven, Jens Randel Nyengaard

Front Cell Neurosci· April 2023

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Capillary function progressively deteriorates in prodromal Alzheimer's disease: A longitudinal MRI perfusion study.
Lasse S Madsen, Rune B Nielsen, Peter Parbo, Rola Ismail, Irene K Mikkelsen

Aging Brain· February 2022

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