Publications by authors named "Li-I Chen"

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In vitro activation of brown adipocyte thermogenesis by fermented hypholomine B-enriched Sanghuangporus sanghuang mycelia through FNDC5/Irisin pathway.
I-Chen Li, Yu-En Chan, Yu-Li Lin, Tzong-Yuan Wu, Liang-Yi Wu, Chin-Chu Chen

Mol Cell Endocrinol· February 2026

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Mycelia Extracts Show Potent Antiviral and Immunomodulatory Effects in H1N1 Influenza Virus-Infected Mice.
I-Chen Li, Yi-Lin Chan, Wen-Ting Lu, Lynn-Huey Chiang, Tsung-Ju Li, Chin-Chu Chen

Foods· November 2025

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GKB202 suppresses endothelin-1/ERK signaling in pancreatic cancer cells: Potential implications for circulating tumor cell regulation.
Yu-Fang Hu, Andy Y Chen, Jun-Way Chang, Shu-Yu Chen, I-Chen Li, Chin-Chu Chen

Biomed Pharmacother· August 2025

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Whole-Genome Sequencing of Three Strains Reveals Potential Metabolites for Boosting Host Immunity Safely.
I-Chen Li, Yueh-Lun Lee, Tsung-Ju Li, You-Shan Tsai, Yen-Lien Chen, Chin-Chu Chen

J Microbiol Biotechnol· October 2024

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A pilot pharmacokinetic and Metabolite identification study of Erinacine A in a Single landrace pig model.
Ying-Yu Chen, Ting-Wei Lin, I-Chen Li, Lin Tsung, Chun-Hsiang Hou, Chin-Chu Chen

Heliyon· September 2024

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Discovery of a New Compound, Erinacerin W, from the Mycelia of , with Immunomodulatory and Neuroprotective Effects.
Jing-Yi Lin, Yen-Po Chen, Ting-Wei Lin, Tsung-Ju Li, Yu-Wen Chen, I-Chen Li, Chin-Chu Chen

Molecules· February 2024

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Phellinus linteus mycelia extract in COVID-19 prevention and identification of its key metabolic compounds profiling using UPLC-QTOF-MS/MS spectrometry.
Tsung-Ju Li, Ting-Wei Lin, Ting-Yu Lu, Chin-Kai Tseng, Chun-Kuang Lin, I-Chen Li, Chin-Chu Chen

Fitoterapia· December 2023

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Hispidin-enriched Sanghuangporus sanghuang mycelia SS-MN4 ameliorate disuse atrophy while improving muscle endurance.
I-Chen Li, Ting-Yu Lu, Ting-Wei Lin, Andy Y Chen, Hsin-Tung Chu, Yen-Lien Chen, Chin-Chu Chen

J Cachexia Sarcopenia Muscle· October 2023

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Nutrition Profile and Animal-Tested Safety of Mycelia Produced by Fermentation in Bioreactors.
I-Chen Li, Lynn-Huey Chiang, Szu-Yin Wu, Yang-Chia Shih, Chin-Chu Chen

Foods· May 2022

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Pilot Study: Nutritional and Preclinical Safety Investigation of Fermented Hispidin-Enriched Mycelia: A Promising Functional Food Material to Improve Sleep.
I-Chen Li, Fang-Chia Chang, Ching-Chuan Kuo, Hsin-Tung Chu, Tsung-Ju Li, Chin-Chu Chen

Front Nutr· January 2022

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Comparison of Reference-Based Assembly and De Novo Assembly for Bacterial Plasmid Reconstruction and AMR Gene Localization in Serovar Schwarzengrund Isolates.
I-Chen Li, Gine-Ye Yu, Jing-Fang Huang, Zeng-Weng Chen, Chung-Hsi Chou

Microorganisms· January 2022

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Hericium erinaceus mycelium ameliorate anxiety induced by continuous sleep disturbance in vivo.
Tsung-Ju Li, Tung-Yen Lee, Yun Lo, Li-Ya Lee, I-Chen Li, Chin-Chu Chen

BMC Complement Med Ther· December 2021

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Delta/Jagged-mediated Notch signaling induces the differentiation of agr2-positive epidermal mucous cells in zebrafish embryos.
Yu-Fen Lu, Da-Wei Liu, I-Chen Li, Jamie Lin, Chien-Ming Wang

PLoS Genet· December 2021

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Comparison of Conventional Molecular and Whole-Genome Sequencing Methods for Differentiating Serovar Schwarzengrund Isolates Obtained from Food and Animal Sources.
I-Chen Li, Rayean Wu, Chung-Wen Hu, Keh-Ming Wu, Zeng-Weng Chen

Microorganisms· September 2021

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Prevalence of IncFIB Plasmids Found among Serovar Schwarzengrund Isolates from Animal Sources in Taiwan Using Whole-Genome Sequencing.
I-Chen Li, Hsiu-Hui Wu, Zeng-Weng Chen, Chung-Hsi Chou

Pathogens· August 2021

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Preclinical Bioavailability, Tissue Distribution, and Protein Binding Studies of Erinacine A, a Bioactive Compound from Mycelia Using Validated LC-MS/MS Method.
Pei-Ching Tsai, Yi-Kai Wu, Jun-Hao Hu, I-Chen Li, Ting-Wei Lin, Chin-Chu Chen

Molecules· July 2021

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Oral Administration of Mycelia Promotes Non-Rapid Eye Movement and Rapid Eye Movement Sleep in Rats.
I-Chen Li, Ting-Wei Lin, Tung-Yen Lee, Yun Lo, Yih-Min Jiang, Chin-Chu Chen

J Fungi (Basel)· May 2021

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Nutritional and 13-Week Subchronic Toxicological Evaluation of Mycelium in Sprague-Dawley Rats.
I-Chen Li, Bi-Hua Yang, Jing-Yi Lin, Shan Lin, Chin-Chu Chen

Int J Environ Res Public Health· January 2021

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plantarum GKM3 and Lactobacillus paracasei GKS6 Supplementation Ameliorates Bone Loss in Ovariectomized Mice by Promoting Osteoblast Differentiation and Inhibiting Osteoclast Formation.
Li-Chan Yang, Shih-Wei Lin, I-Chen Li, Yen-Po Chen, Shih-Yang Tzu, Chin-Chu Chen, Yen-Lien Chen

Nutrients· June 2020

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Optimized production and safety evaluation of hispidin-enriched mycelia.
I-Chen Li, Chang Cheng Chen, Sen-Je Sheu, I-Hsuan Huang, Chin-Chu Chen

Food Sci Nutr· April 2020

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Erinacine A-enriched Hericium erinaceus mycelia promotes longevity in Drosophila melanogaster and aged mice.
I-Chen Li, Li-Ya Lee, Ying-Ju Chen, Ming-Yu Chou, Ming-Fu Wang, Wan-Ping Chen, Yen-Po Chen, Chin-Chu Chen

PLoS One· January 2020

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Thirteen-Week Oral Toxicity Evaluation of Erinacine AEnriched Lion's Mane Medicinal Mushroom, Hericium erinaceus (Agaricomycetes), Mycelia in Sprague-Dawley Rats.
Li-Ya Lee, I-Chen Li, Wan-Ping Chen, Yueh-Ting Tsai, Chin-Chu Chen

Int J Med Mushrooms· August 2019

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Analysis of steroid hormones in shell eggs from layer breeds common to Taiwan by liquid chromatography-tandem mass spectrometry.
I-Chen Li, Wen-Yuan Yang, Chung-Hsi Chou, Yi-Chen Chen, Su-Lien Kuo

Food Sci Nutr· July 2019

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Absolute Bioavailability, Tissue Distribution, and Excretion of Erinacine S in Mycelia.
Jun-Hao Hu, I-Chen Li, Ting-Wei Lin, Wan-Ping Chen, Li-Ya Lee, Chin-Chu Chen

Molecules· April 2019

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