Publications by authors named "Li-ming Gan"

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RNA interference therapy targeting coagulation factor XI - a first-in-human trial of RBD4059.
Anders Gabrielsen, Sebastian Ueckert, Catarina Nilsson, Ann-Charlotte Egnell, Jing Fu, Li-Ming Gan

Blood Adv· January 2026

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Persistent Binge Drinking History Associated With Advanced Liver Fibrosis and All-Cause Mortality in MetALD.
Zhe-Kun Xiong, Ru-Tao Lin, Bi-Wei Chen, Xin Xin, Tao-Ying Deng, Li-Ming Gan

Aliment Pharmacol Ther· December 2025

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A potent GalNAc-siRNA drug, RBD1016, leads to sustained HBsAg reduction and seroconversion in mouse models of HBV infection.
Shuquan Zheng, Huiqing Cao, Min Zhang, Chun Guo, Xu Yan, Li-Ming Gan

Mol Ther Nucleic Acids· September 2025

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Circulating soluble LOX-1 and patient prognosis after an acute coronary syndrome.
Alexandru Schiopu, Sara Svedlund, Gayathri Narasimhan, Bi Juin Loong, Troels Yndigegn, Li-Ming Gan

Heart· September 2025

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Inhibition of Factor XI Using RBD4059: A Novel GalNAc-siRNA With Potent and Durable Antithrombotic Effects.
Junshi Liang, Sofia Nilsson, Johannes Wikström, Huiqing Cao, Shuquan Zheng, Li-Ming Gan

JACC Basic Transl Sci· June 2025

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The efficacy and safety of ISIS 449884 injection as monotherapy in patients with type 2 diabetes: A randomized phase II study.
Linong Ji, Leili Gao, Zhikai Feng, Guoliang Chen, Jing Fu, Erin Morgan, Li-Ming Gan

Diabetes Obes Metab· November 2024

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SGLT2 inhibition improves coronary flow velocity reserve and contractility: role of glucagon signaling.
Sven O Göpel, Damilola Adingupu, Jue Wang, Elizaveta Semenova, Margareta Behrendt, Li-Ming Gan

Cardiovasc Diabetol· November 2024

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Clinical efficacy of lenvatinib, trans-arterial chemoembolization, and PD-1/L1 inhibitors in advanced hepatocellular carcinoma: a systematic review and network meta-analysis.
YiFeng Liang, LiMing Gan, DeJin Zeng, LangHua Lin, ZheKun Xiong

Clin Transl Oncol· October 2024

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ISIS 449884 Injection Add-On to Metformin in Patients with Type 2 Diabetes: A Randomized, Double-Blind, Placebo-Controlled, Phase II Clinical Study.
Linong Ji, Leili Gao, Zhikai Feng, Guoliang Chen, Jing Fu, Erin Morgan, Li-Ming Gan

Diabetes Ther· October 2024

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Publisher Correction to: ISIS 449884 Injection Add‑On to Metformin in Patients with Type 2 Diabetes: A Randomized, Double‑Blind, Placebo‑Controlled, Phase II Clinical Study.
Linong Ji, Leili Gao, Zhikai Feng, Guoliang Chen, Jing Fu, Erin Morgan, Li-Ming Gan

Diabetes Ther· October 2024

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Cardiometabolic biomarker patterns associated with cardiac MRI defined fibrosis and microvascular dysfunction in patients with heart failure with preserved ejection fraction.
Connor Siggins, Jonathan A Pan, Adrián I Löffler, Yang Yang, Peter W Shaw, Li-Ming Gan

Front Cardiovasc Med· March 2024

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Myeloperoxidase Inhibition in Heart Failure With Preserved or Mildly Reduced Ejection Fraction: SATELLITE Trial Results.
Carolyn S P Lam, Lars H Lund, Sanjiv J Shah, Adriaan A Voors, David Erlinge, Li-Ming Gan

J Card Fail· January 2024

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Safety and Feasibility Using a Fluid-Filled Wire to Avoid Hydrostatic Errors in Physiological Intracoronary Measurements.
Truls Råmunddal, Christian Dworeck, Petronella Torild, Sofie Andréen, Li-Ming Gan

Cardiol Res Pract· January 2024

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External validation of a deep learning algorithm for automated echocardiographic strain measurements.
Peder L Myhre, Chung-Lieh Hung, Matthew J Frost, Zhubo Jiang, Wouter Ouwerkerk, Li-Ming Gan

Eur Heart J Digit Health· January 2024

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Diagnostic Value of Contrast-Enhanced Ultrasonography for Catheter-Related Right Brachiocephalic Vein and Superior Vena Cava Lesions in Patients Undergoing Hemodialysis-A Pilot Study.
Yu Fen, Wang Yin, Gan Li-Ming, Fu Hui-Ling, Xiao Wei

J Ultrasound Med· December 2023

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Regional differences and coronary microvascular dysfunction in heart failure with preserved ejection fraction.
Mikael Erhardsson, Ulrika Ljung Faxén, Ashwin Venkateshvaran, Sara Svedlund, Antti Saraste, Li-Ming Gan

ESC Heart Fail· December 2023

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Myeloperoxidase Inhibition Reverses Biomarker Profiles Associated With Clinical Outcomes in HFpEF.
Erik Michaëlsson, Lars H Lund, Camilla Hage, Sanjiv J Shah, Adriaan A Voors, Li-Ming Gan

JACC Heart Fail· July 2023

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Ticagrelor Treatment is Associated With Increased Coronary Flow Reserve in Survivors of Myocardial Infarction.
Kristina Torngren, Rebecca Rylance, Li-Ming Gan, Elmir Omerovic, Sara Svedlund

Heart Lung Circ· June 2023

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Feasibility of high-dose tadalafil and effects on insulin resistance in well-controlled patients with type 2 diabetes (MAKROTAD): a single-centre, double-blind, randomised, placebo-controlled, cross-over phase 2 trial.
Emanuel Fryk, Vagner Ramon Rodrigues Silva, Marco Bauzá-Thorbrügge, Martin Schmelz, Li-Ming Gan

EClinicalMedicine· May 2023

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Direct intramyocardial injection of VEGF mRNA in patients undergoing coronary artery bypass grafting.
Vesa Anttila, Antti Saraste, Juhani Knuuti, Marja Hedman, Pekka Jaakkola, Li-Ming Gan

Mol Ther· March 2023

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Association of epicardial adipose tissue with proteomics, coronary flow reserve, cardiac structure and function, and quality of life in heart failure with preserved ejection fraction: insights from the PROMIS-HFpEF study.
Ashwin Venkateshvaran, Ulrika Ljung Faxen, Camilla Hage, Erik Michaëlsson, Sara Svedlund, Li-Ming Gan

Eur J Heart Fail· December 2022

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Safety and efficacy of the 5-lipoxygenase-activating protein inhibitor AZD5718 in patients with recent myocardial infarction: The phase 2a FLAVOUR study.
Eva Prescott, Oskar Angerås, David Erlinge, Erik L Grove, Marja Hedman, Li-Ming Gan

Int J Cardiol· October 2022

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Targeting inflammation for the treatment of Diabetic Kidney Disease: a five-compartment mechanistic model.
Alexis Hofherr, Julie Williams, Li-Ming Gan, Magnus Söderberg, Pernille B L Hansen

BMC Nephrol· June 2022

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Sex differences in proteomic correlates of coronary microvascular dysfunction among patients with heart failure and preserved ejection fraction.
Chanchal Chandramouli, Tay W Ting, Jasper Tromp, Anubha Agarwal, Sara Svedlund, Li-Ming Gan

Eur J Heart Fail· April 2022

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A mechanistic framework for cardiometabolic and coronary artery diseases.
Simon Koplev, Marcus Seldin, Katyayani Sukhavasi, Raili Ermel, Shichao Pang, Li-Ming Gan

Nat Cardiovasc Res· January 2022

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