Publications by authors named "Lindsey D Goodman"

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Distinct systemic impacts of Aβ42 and Tau revealed by whole-organism snRNA-seq.
Ye-Jin Park, Tzu-Chiao Lu, Tyler Jackson, Lindsey D Goodman, Lindsey Ran, Jiaye Chen, Chung-Yi Liang, Erin Harrison, Christina Ko, Xi Chen

Neuron· July 2025

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Revealing the nervous system requirements of Alzheimer disease risk genes in Drosophila.
Jennifer M Deger, Shabab B Hannan, Mingxue Gu, Colleen E Strohlein, Lindsey D Goodman

Am J Hum Genet· December 2025

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Revealing the nervous system requirements of Alzheimer's disease risk genes in .
Jennifer M Deger, Shabab B Hannan, Mingxue Gu, Colleen E Strohlein, Lindsey D Goodman

bioRxiv· July 2025

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Alzheimer's disease protective allele of Clusterin modulates neuronal excitability through lipid-droplet-mediated neuron-glia communication.
Xiaojie Zhao, Yan Li, Siwei Zhang, Ari Sudwarts, Hanwen Zhang, Lindsey D Goodman

Mol Neurodegener· May 2025

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Does glial lipid dysregulation alter sleep in Alzheimer's and Parkinson's disease?
Lindsey D Goodman, Matthew J Moulton, Guang Lin, Hugo J Bellen

Trends Mol Med· October 2024

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Tau is required for glial lipid droplet formation and resistance to neuronal oxidative stress.
Lindsey D Goodman, Isha Ralhan, Xin Li, Shenzhao Lu, Matthew J Moulton

Nat Neurosci· October 2024

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Alzheimer's disease protective allele of modulates neuronal excitability through lipid-droplet-mediated neuron-glia communication.
Xiaojie Zhao, Yan Li, Siwei Zhang, Ari Sudwarts, Hanwen Zhang, Lindsey D Goodman

medRxiv· August 2024

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Glial lipid droplets resolve ROS during sleep.
Lindsey D Goodman, Matthew J Moulton, Hugo J Bellen

Nat Neurosci· April 2024

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Whole organism snRNA-seq reveals systemic peripheral changes in Alzheimer's Disease fly models.
Ye-Jin Park, Tzu-Chiao Lu, Tyler Jackson, Lindsey D Goodman, Lindsey Ran

bioRxiv· March 2024

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Autolysosomal exocytosis of lipids protect neurons from ferroptosis.
Isha Ralhan, Jinlan Chang, Matthew J Moulton, Lindsey D Goodman, Nathanael Y J Lee

J Cell Biol· June 2023

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Author Correction: Toxic expanded GGGGCC repeat transcription is mediated by the PAF1 complex in C9orf72-associated FTD.
Lindsey D Goodman, Mercedes Prudencio, Nicholas J Kramer, Luis F Martinez-Ramirez, Ananth R Srinivasan

Nat Neurosci· March 2023

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PDPN marks a subset of aggressive and radiation-resistant glioblastoma cells.
Aram S Modrek, Eskil Eskilsson, Ravesanker Ezhilarasan, Qianghu Wang, Lindsey D Goodman

Front Oncol· August 2022

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Recent insights into the role of glia and oxidative stress in Alzheimer's disease gained from Drosophila.
Lindsey D Goodman, Hugo J Bellen

Curr Opin Neurobiol· February 2022

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Neuronal ROS-induced glial lipid droplet formation is altered by loss of Alzheimer's disease-associated genes.
Matthew J Moulton, Scott Barish, Isha Ralhan, Jinlan Chang, Lindsey D Goodman

Proc Natl Acad Sci U S A· December 2021

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TNPO2 variants associate with human developmental delays, neurologic deficits, and dysmorphic features and alter TNPO2 activity in Drosophila.
Lindsey D Goodman, Heidi Cope, Zelha Nil, Thomas A Ravenscroft, Wu-Lin Charng

Am J Hum Genet· September 2021

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New Roles for Canonical Transcription Factors in Repeat Expansion Diseases.
Lindsey D Goodman, Nancy M Bonini

Trends Genet· February 2020

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Repeat-associated non-AUG (RAN) translation mechanisms are running into focus for GGGGCC-repeat associated ALS/FTD.
Lindsey D Goodman, Nancy M Bonini

Prog Neurobiol· December 2019

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Toxic expanded GGGGCC repeat transcription is mediated by the PAF1 complex in C9orf72-associated FTD.
Lindsey D Goodman, Mercedes Prudencio, Nicholas J Kramer, Luis F Martinez-Ramirez, Ananth R Srinivasan

Nat Neurosci· June 2019

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eIF4B and eIF4H mediate GR production from expanded G4C2 in a Drosophila model for C9orf72-associated ALS.
Lindsey D Goodman, Mercedes Prudencio, Ananth R Srinivasan, Olivia M Rifai, Virginia M-Y Lee

Acta Neuropathol Commun· April 2019

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Drosophila Ref1/ALYREF regulates transcription and toxicity associated with ALS/FTD disease etiologies.
Amit Berson, Lindsey D Goodman, Ashley N Sartoris, Charlton G Otte, James A Aykit

Acta Neuropathol Commun· April 2019

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ABT-888 restores sensitivity in temozolomide resistant glioma cells and xenografts.
Alice L Yuan, Christian B Ricks, Alexandra K Bohm, Xueqing Lun, Lori Maxwell, Lindsey D Goodman

PLoS One· February 2019

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Dipeptide repeat proteins activate a heat shock response found in C9ORF72-ALS/FTLD patients.
Daniel A Mordes, Mercedes Prudencio, Lindsey D Goodman, Joseph R Klim, Rob Moccia

Acta Neuropathol Commun· July 2018

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A gene expression signature predicts recurrence-free survival in meningioma.
Adriana Olar, Lindsey D Goodman, Khalida M Wani, Nicholas S Boehling, Devi S Sharma

Oncotarget· March 2018

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Spt4 selectively regulates the expression of C9orf72 sense and antisense mutant transcripts.
Nicholas J Kramer, Yari Carlomagno, Yong-Jie Zhang, Sandra Almeida, Casey N Cook, Lindsey D Goodman

Science· August 2016

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A fly model for the CCUG-repeat expansion of myotonic dystrophy type 2 reveals a novel interaction with MBNL1.
Zhenming Yu, Lindsey D Goodman, Shin-Yi Shieh, Michelle Min, Xiuyin Teng

Hum Mol Genet· February 2015

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